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APC anti-human HLA-B7 Antibody

Pricing & Availability
Clone
BB7.1 (See other available formats)
Regulatory Status
RUO
Other Names
HLA-A7, HLA-B*07, HLA Class I histocompatibility antigen B alpha chain
Isotype
Mouse IgG1, κ
Ave. Rating
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Product Citations
publications
BB7dot1_APC_HLA-B7_Antibody_011717
Human peripheral blood lymphocytes were stained with APC HLA-B7 (clone BB7.1, filled histogram) or APC mouse IgG1, κ isotype control (open histogram).
  • BB7dot1_APC_HLA-B7_Antibody_011717
    Human peripheral blood lymphocytes were stained with APC HLA-B7 (clone BB7.1, filled histogram) or APC mouse IgG1, κ isotype control (open histogram).
Compare all formats See APC spectral data
Cat # Size Price Quantity Check Availability Save
372405 25 tests £86
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372406 100 tests £215
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Description

HLA-B belongs to the HLA class I heavy chain paralogues. HLA-B7 is a serotype of HLA-B and one of the common HLA types. MHC class I heavy chains associate with β2-microglobulin and are expressed on nearly all nucleated cells. MHC class I molecules are involved in the presentation of of antigens to CD8+ T cells and thereby play an important role in cell-mediated immune responses and immune surveillance.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Papain solubilized HLA antigen, B7.
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.

Excitation Laser
Red Laser (633 nm)
Application References

(PubMed link indicates BioLegend citation)
  1. Dellgren C, et al. 2015. PLoS One 10:e0135385.
  2. Brodsky F, et al. 1979. Immunol. Rev. 47:3.
  3. Rancan C, et al. 2015. PLoS Pathog. 11:e1004906.
  4. Levering W, et al. 2000. Cytometry 42:95.
RRID
AB_2650775 (BioLegend Cat. No. 372405)
AB_2650775 (BioLegend Cat. No. 372406)

Antigen Details

Structure
Ig superfamily.
Distribution

Nearly all cells from HLA-B*07 individuals.

Function
Antigen peptide presentation.
Ligand/Receptor
TCR, CD8.
Biology Area
Immunology
Molecular Family
MHC Antigens
Gene ID
3106 View all products for this Gene ID
UniProt
View information about HLA-B7 on UniProt.org
Go To Top Version: 1    Revision Date: 01/17/2017

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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