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PE/Cyanine7 anti-mouse F4/80 Antibody

Pricing & Availability
Clone
BM8 (See other available formats)
Regulatory Status
RUO
Other Names
EMR1, Ly71
Isotype
Rat IgG2a, κ
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Product Citations
publications
BM8_PECy7_122607
Thioglycolate-elicited BALB/c mouse peritoneal macrophages stained with BM8 PE/Cyanine7
  • BM8_PECy7_122607
    Thioglycolate-elicited BALB/c mouse peritoneal macrophages stained with BM8 PE/Cyanine7
Compare all formats See PE/Cyanine7 spectral data
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123113 25 µg £72
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123114 100 µg £208
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Description

F4/80, also known as EMR1 or Ly71, is a 160 kD glycoprotein of the epidermal growth factor (EGF)-transmembrane 7 (TM7) family. F4/80 has been widely used as a murine macrophage marker. It is expressed on a majority of tissue macrophages, including macrophages in the lung, gut, peritoneal cavity, thymus, and red pulp of the spleen, Kupffer cells, Langerhans cells, microglia, and certain dendritic cells. It is not expressed on macrophages located in the T cell areas of the spleen, lymph node, or Peyer's patch. The biological ligand of F4/80 has not been identified, but it has been reported that F4/80 is required for the induction of CD8+ T cells-mediated peripheral tolerance.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Murine macrophages
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with PE/Cyanine7 under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application Notes

Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen sections1,2 and formalin-fixed paraffin-embedded sections6,7, Western blotting, and spatial biology (IBEX)12,13.

Application References

(PubMed link indicates BioLegend citation)
  1. Schaller E, et al. 2002. Mol. Cell. Biol. 22:8035. (IHC)
  2. Stevceva L, et al. 2001. BMC Clin Pathol. 1:3. (IHC)
  3. Kobayashi M, et al.2008. J. Leukoc. Biol. 83:1354. PubMed
  4. Poeckel D, et al. 2009. J. Biol Chem. 284:21077. PubMed
  5. Glass AM, et al. 2013. J. Immunol. 190:4830. PubMed
  6. Koehm S, et al. 2007. J. Allergy Clin. Immunol. 120:570. (IHC)
  7. Rankin AL, et al. 2010. J. Immunol. 184:1526. (IHC)
  8. Sasi SP, et al. 2014. J Biol Chem. 289:14178. PubMed
  9. Thakus VS, et al. 2014. Toxicol Lett. 230:322. PubMed
  10. Watson NB, et al. 2015. J Immunol. 194:2796. PubMed
  11. Hirakawa H, et al. 2015. PLoS One. 10:119360. PubMed
  12. Radtke AJ, et al. 2020. Proc Natl Acad Sci U S A. 117:33455-65. (SB) PubMed
  13. Radtke AJ, et al. 2022. Nat Protoc. 17:378-401. (SB) PubMed
Product Citations
  1. Fan G, et al. 2021. Cell Death Dis. 12:73. PubMed
  2. Garo LP, et al. 2021. Nat Commun. 12:2419. PubMed
  3. Su Y, et al. 2022. J Hematol Oncol. 15:99. PubMed
  4. Taranto D, et al. 2021. Curr Protoc. 1:e147. PubMed
  5. Russler-Germain EV, et al. 2021. Immunity. 54:2547. PubMed
  6. Gerlach BD, et al. 2021. Cell Metab. 33:2445. PubMed
  7. Mills EL, et al. 2022. Cell Metab. 34:140. PubMed
  8. Gadipudi LL, et al. 2022. Clin Sci (Lond). 136:643. PubMed
  9. Van Deren DA, et al. 2022. Development. 149: . PubMed
  10. Liu K, et al. 2022. J Cell Biol. 221: . PubMed
  11. Yue Y, et al. 2022. Nat Biomed Eng. 6:898. PubMed
  12. Dolfi B, et al. 2022. Cell Rep. 39:110949. PubMed
  13. Silva Pereira S, et al. 2022. Elife. 11: . PubMed
  14. Akalu YT, et al. 2022. Elife. 11: . PubMed
  15. Liang Y, et al. 2022. Theranostics. 12:7729. PubMed
  16. Morrow RJ, et al. 2022. Cells. 11: . PubMed
  17. Cheng P, et al. 2023. Pharmacol Res. 188:106643. PubMed
  18. Niu J, et al. 2023. Nat Commun. 14:642. PubMed
  19. Chun J, et al. 2023. Cancers (Basel). 15: . PubMed
  20. Georgiev GI, et al. 2022. Cell Chem Biol. 29:811. PubMed
  21. Ajay AK, et al. 2022. Cell Rep. 38:110473. PubMed
  22. Chen K, et al. 2022. Adv Sci (Weinh). 9:e2104106. PubMed
  23. Gomez-Salinero JM, et al. 2022. Cell Stem Cell. 29:593. PubMed
  24. Friedman D, et al. 2022. J Immunol. 208:1845. PubMed
  25. Doni A, et al. 2015. J Exp Med. 212:905. PubMed
  26. Orberg E, et al. 2016. Mucosal Immunol. 10.1038/mi.2016.53. PubMed
  27. Krasniewski LK, et al. 2022. Elife. 11:. PubMed
  28. Li Y, et al. 2023. Adv Mater. 35:e2208923. PubMed
  29. Wu Z, et al. 2023. EMBO Rep. 24:e56524. PubMed
  30. Gu J, et al. 2023. J Cell Biochem. 124:557. PubMed
  31. Aso K, et al. 2023. Nat Commun. 14:984. PubMed
  32. Zhong WJ, et al. 2023. J Transl Med. 21:179. PubMed
  33. Cheng K, et al. 2023. Small. 19:e2300125. PubMed
  34. Dang YZ, et al. 2023. Neoplasma. 70:123. PubMed
  35. Seclì L, et al. 2023. J Immunother Cancer. 11:. PubMed
  36. Ji Y, et al. 2023. Nat Cell Biol. 25:726. PubMed
  37. Ishida K, et al. 2023. Front Immunol. 14:1111729. PubMed
  38. Brigo N, et al. 2023. Cells. 12:. PubMed
  39. Tsugawa H, et al. 2023. PLoS Pathog. 19:e1011139. PubMed
  40. Oh J, et al. 2023. Nat Commun. 14:3278. PubMed
  41. Michela Miani et al. 2018. Cell metabolism. 28(4):557-572 . PubMed
  42. Hou X, et al. 2020. Cell Reports. 28(1):172-189.e7.. PubMed
  43. Sierro F, et al. 2017. Immunity. 47:374. PubMed
  44. Yonemitsu K, et al. 2022. Sci Rep. 12:12007. PubMed
  45. Schloss MJ, et al. 2022. Nat Immunol. 23:605. PubMed
  46. Li X, et al. 2022. Nat Commun. 13:2794. PubMed
  47. Dando SJ, et al. 2021. Invest Ophthalmol Vis Sci. 62:10. PubMed
  48. Tripathi H, et al. 2020. J Mol Cell Cardiol. 149:95. PubMed
  49. Delvecchio FR, et al. 2021. Cell Mol Gastroenterol Hepatol. 12:1543. PubMed
  50. Aggen DH, et al. 2020. Clin Cancer Res. . PubMed
  51. Cornax I, et al. 2021. Microorganisms. 9:00. PubMed
  52. Lauterbach MA, et al. 2020. Immunity. 51(6):997-1011.e7.. PubMed
  53. Poh AR, et al. 2017. Cancer Cell. 31:563. PubMed
  54. Fachi JL et al. 2019. Cell reports. 27(3):750-761 . PubMed
  55. Sadek J, et al. 2021. EMBO Mol Med. 13:e13591. PubMed
  56. Frank AC, et al. 2021. Theranostics. 11:7570. PubMed
  57. Rodriguez-García A, et al. 2021. Nat Commun. 12:877. PubMed
  58. Kesavan R, et al. 2021. Int J Mol Sci. 22:. PubMed
  59. Sasse C, et al. 2022. Pathogens. 11:. PubMed
  60. Adachi Y, et al. 2022. Nat Commun. 13:5117. PubMed
  61. Weigert A, et al. 2022. Nat Commun. 13:6078. PubMed
  62. Saxena A, et al. 2013. J Immunol. 191:4838. PubMed
  63. Giordano C, et al. 2014. Hum Mol Genet. . PubMed
  64. Chou YJ, et al. 2020. Sci Rep. 10:8422. PubMed
  65. Andreas N, et al. 2021. Arthritis Res Ther. 23:222. PubMed
  66. Huard A, et al. 2021. J Immunol. 206:1058. PubMed
  67. Achmus L, et al. 2020. Front Neurol. 11:577971. PubMed
  68. Nagatake T, et al. 2022. Mucosal Immunol. 15:289. PubMed
  69. Cheng G, et al. 2021. iScience. 24:102673. PubMed
  70. Allegrezza M, et al. 2016. Cancer Res . 76: 6253 - 6265. PubMed
  71. Coppo M, et al. 2016. Nat Commun. 7:12254. PubMed
  72. Shang W, et al. 2019. J Diabetes Res. 2019:5641271. PubMed
  73. Shikatani EA et al. 2019. Cell Rep. 27(8):2304-2312 . PubMed
  74. Park JA, et al. 2021. J Hematol Oncol. 14:142. PubMed
  75. Patnode M, et al. 2013. J Biol Chem. 288:26533. PubMed
  76. Starkl P, et al. 2020. Immunity. 53(4):793-804.e9. PubMed
  77. Damal Villivalam S, et al. 2020. Nat Commun. 4313:11. PubMed
  78. Han Y et al. 2019. Cell reports. 27(3):835-846 . PubMed
  79. Currier MA, et al. 2017. Oncotarget. 8:17412. PubMed
  80. Hao F, et al. 2021. Proc Natl Acad Sci U S A. 118:. PubMed
  81. Sive J, et al. 2015. Leukemia. . PubMed
  82. Sharma S, et al. 2015. J Immunol. 194:5529. PubMed
  83. Fujikura D, et al. 2013. PLoS One. 8:e55321. PubMed
  84. Koh EH, et al. 2018. Diabetes. 67(12). PubMed
  85. Luo W, et al. 2019. Mol Med Rep. 20:1007. PubMed
  86. Shimoda A, et al. 2017. Biochem Biophys Res Commun. 10.1016/j.bbrc.2017.07.126. PubMed
  87. Cheng K, et al. 2021. Nat Commun. 12:2041. PubMed
  88. Wu X, et al. 2021. Elife. 10:. PubMed
  89. Roy R, et al. 2022. Elife. 11:. PubMed
  90. Stutchfield B, et al. 2015. Gastroenterology. 149: 1896-1909.e14. PubMed
  91. Jondle C, et al. 2016. J Immunol. 196: 3088-3096. PubMed
  92. Szafran BN, et al. 2021. Chemical Research in Toxicology. 34(6):1556-1571. PubMed
  93. Maston LD, et al. 2017. Am J Physiol Lung Cell Mol Physiol. 312:L609. PubMed
  94. Zhang S, et al. 2019. Cell Metab. 29:443. PubMed
  95. Qu J, et al. 2018. J Immunol Res. 2018:7519856. PubMed
  96. Terashima Y, et al. 2020. Nat Commun. 11:609. PubMed
  97. Xiao Y, et al. 2022. Clin Transl Med. 12:e1071. PubMed
  98. Smith AS, et al. 2022. J Immunother Cancer. 10:. PubMed
  99. Tomlinson KL, et al. 2021. Nat Commun. 12:1399. PubMed
  100. Wu MY, et al. 2021. Autophagy. 17:1096. PubMed
  101. Kornstädt L, et al. 2021. Front Immunol. 11:607048. PubMed
  102. Ajina R, et al. 2021. Cancer Immunol Res. 9:386. PubMed
  103. Tay S, et al. 2014. J Immunol. 193:2087. PubMed
  104. Linde N, et al. 2018. Nat Commun. 9:21. PubMed
  105. Morimoto A, et al. 2021. Nat Commun. 12:2136. PubMed
  106. Lu X, et al. 2020. Sci Transl Med. 12:. PubMed
  107. Russler-Germain EV, et al. 2021. Elife. 10:. PubMed
  108. Ganguly K, et al. 2022. Front Immunol. 13:930449. PubMed
  109. Weber G, et al. 2014. J Exp Med. 211:1243. PubMed
  110. Francis M, et al. 2017. Toxicol Sci. 155(1):182-195. PubMed
  111. Wang ECE, et al. 2019. Cell Stem Cell. 24:654. PubMed
  112. Hulsmans M et al. 2017. Cell. 169(3):510-522 . PubMed
  113. Zheng Z, et al. 2020. Cell Death Dis. 0.684722222. PubMed
  114. Zhao X, et al. 2022. Nat Protoc. 17:2240. PubMed
  115. Yong L, et al. 2022. Nat Commun. 13:4255. PubMed
  116. Golden TN, et al. 2022. Front Pharmacol. 12:761496. PubMed
  117. Garland KM, et al. 2021. Front Immunol. 12:753472. PubMed
  118. Reinfeld BI, et al. 2021. Nature. 593:282. PubMed
  119. Xu Z, et al. 2020. Cancer Immunol Res. 1354:8. PubMed
  120. Brigas HC, et al. 2021. Cell Reports. 36(9):109574. PubMed
  121. Volberding PJ, et al. 2021. Cell Reports. 35(8):109160. PubMed
  122. Mojumdar K, et al. 2014. EMBO Mol Med. 6:1476. PubMed
  123. Torroella-Kouri M, et al. 2009. Cancer Res. 69:4800. PubMed
  124. Frodermann V, et al. 2019. Nat Med. 25:1761. PubMed
  125. Xu X, et al. 2018. Cell. 175:1336. PubMed
  126. Oertel S, et al. 2017. Cell Mol Life Sci. 10.1007/s00018-017-2518-9. PubMed
  127. Alameh MG, et al. 2021. Immunity. 54:2877. PubMed
  128. Aktories P, et al. 2022. Cell Rep Methods. 2:100260. PubMed
  129. Chiu Y, et al. 2014. J Immunol. 193:2207. PubMed
  130. Hamilton J, et al. 2015. J Immunol. 194:5022. PubMed
  131. Mangum L, et al. 2016. Toxicol Sci. 150: 169 - 177. PubMed
  132. Wanner-Seleznik GM, et al. 2020. Immunohorizons. 0.644444444. PubMed
  133. Tripathi H, et al. 2020. Stem Cell Rev Rep. 0.953472222. PubMed
  134. Engler AE, et al. 2020. Cell Reports. 33(13):108553. PubMed
  135. Deerhake ME, et al. 2021. Immunity. 54(3):484-498.e8. PubMed
  136. Lim CX, et al. 2020. Cell Rep. 3793:30. PubMed
  137. Chung L et al. 2018. Cell host & microbe. 23(2):203-214 . PubMed
  138. Medler TR et al. 2018. Cancer cell. 34(4):561-578 . PubMed
  139. Xiong X et al. 2019. Mol Cell. 75(3):644-660 . PubMed
  140. Sun P, et al. 2022. Nat Commun. 13:6562. PubMed
  141. Pathania AS, et al. 2022. Mol Ther Oncolytics. 25:308. PubMed
  142. Bachy S, et al. 2022. iScience. 25:103758. PubMed
  143. Anderson AE, et al. 2022. NPJ Regen Med. 7:6. PubMed
  144. Maulloo CD, et al. 2021. Front Immunol. 12:714842. PubMed
  145. Park HB, et al. 2020. Nat Microbiol. 1319:5. PubMed
  146. Li C, et al. 2021. Cell Metabolism. 33(8):1610-1623.e5. PubMed
  147. Yamakawa D, et al. 2021. Cell Reports. 34(10):108817. PubMed
  148. Ren Y, et al. 2020. Stem Cell Res Ther. 0.743055556. PubMed
  149. Alonso-Herranz L, et al. 2020. Elife. 9:00. PubMed
  150. Maisel D, et al. 2016. PLoS One. 11: 0159716. PubMed
  151. Kim P, et al. 2015. Infect Immun . 83: 2992 - 3002. PubMed
  152. Ballet R, et al. 2014. PLoS Pathog. 10:1004550. PubMed
  153. Liu Z, et al. 2020. Cell. 178(6):1509-1525.e19.. PubMed
  154. Choi EW, et al. 2020. Sci Rep. 10:12001. PubMed
  155. Yamada KJ, et al. 2020. PLoS Pathog. 16:e1008354. PubMed
  156. Roy AG, et al. 2021. Int J Mol Sci. 22:. PubMed
  157. Zeng Q, et al. 2022. iScience. 25:105151. PubMed
  158. Ahn D, et al. 2021. Cell Reports. 35(9):109196. PubMed
  159. Efremova M, et al. 2018. Nat Commun. 9:32. PubMed
  160. Su W et al. 2019. Cancer Cell. 36(2):139-155 . PubMed
  161. Quenum Zangbede FO, et al. 2018. J Neurosci. 38:6737. PubMed
  162. Matsumura T, et al. 2022. Nat Commun. 13:7064. PubMed
  163. Cheng HW, et al. 2022. Nat Commun. 13:2027. PubMed
  164. Stevenson ER, et al. 2022. J Pharmacol Exp Ther. 382:356. PubMed
  165. Baranwal G, et al. 2021. Physiol Rep. 9:e15094. PubMed
  166. Mendelsohn AC, et al. 2020. Am J Physiol Cell Physiol. 319:C997. PubMed
  167. Fujii T, et al. 2021. Bone Res. 9:4. PubMed
  168. Li J, et al. 2020. FASEB J. 34:3091. PubMed
  169. Hirata SI, et al. 2020. Allergy. 75:1939. PubMed
  170. Heim CE, et al. 2020. Nature Microbiology. 5(10):1271-1284. PubMed
  171. Tozuka M, et al. 2016. J Dermatol Sci. 82: 38-45. PubMed
  172. Sharif O, et al. 2013. J Immunol. 190:5640. PubMed
  173. Song M, et al. 2013. Am J Pathol. 182:1308. PubMed
  174. Cai B, et al. 2020. Cell Metabolism. 31(2):406-421.e7.. PubMed
  175. Nabet BY et al. 2017. Cell. 170(2):352-366 . PubMed
  176. Ponzetta A, et al. 2020. Cell. 178(2):346-360.e24.. PubMed
  177. Nagatake T, et al. 2018. J Allergy Clin Immunol. 142:470. PubMed
  178. Vasamsetti SB, et al. 2018. Immunity. 49:93. PubMed
  179. Chu LH, et al. 2018. Nat Commun. 9:996. PubMed
  180. Fletcher P, et al. 2021. J Toxicol Environ Health A. 84:152. PubMed
  181. Njock MS, et al. 2022. J Extracell Vesicles. 11:e12228. PubMed
  182. INAGAWA H, et al. 2016. In Vivo. 30: 205 - 211. PubMed
  183. Wedekind MF, et al. 2021. iScience. 24(7):102759. PubMed
  184. Clemente C, et al. 2018. Nat Commun. 9:910. PubMed
  185. Laban H, et al. 2018. J Cell Biol. 217:1503. PubMed
  186. Li C, et al. 2018. Cell. 174:285. PubMed
  187. Nalbandian A, et al. 2017. Inflammation. 40:21:00. PubMed
  188. Zhao Y, et al. 2020. Immunity. 51(6):1059-1073.e9.. PubMed
  189. Zhu K, et al. 2022. EMBO Rep. 23:e54499. PubMed
  190. Rao L, et al. 2020. Nat Commun. 11:4909. PubMed
  191. Bell CR, et al. 2022. Nat Commun. 13:2063. PubMed
  192. Dallari S, et al. 2021. Cell Host Microbe. 29(6):1014-1029.e8. PubMed
  193. Yun H, et al. 2020. Immunity. 53(5):1050-1062.e5. PubMed
  194. Chan M, et al. 2013. J Cell Sci. 126:3948. PubMed
  195. Muchenditsi A, et al. 2017. Am J Physiol Gastrointest Liver Physiol. 313:G39. PubMed
  196. Grayczyk JP et al. 2017. Cell host & microbe. 22(5):678-687 . PubMed
  197. Clemente–Casares X, et al. 2017. Immunity. 47:974. PubMed
  198. Zhang Z, et al. 2020. Nature. 579:415. PubMed
  199. Zhang L, et al. 2021. Front Mol Biosci. 8:647647. PubMed
  200. Montes de Oca M, et al. 2016. PLoS Pathog. 12: 1005398. PubMed
  201. Senatus L, et al. 2020. JCI Insight. 5:00. PubMed
  202. Urbanska AM, et al. 2020. Cancer Biother Radiopharm. 35:459. PubMed
  203. Frank AC, et al. 2019. Nat Commun. 10:1135. PubMed
  204. Zhang C, et al. 2018. Cell Res. 28:323. PubMed
  205. Yoshida H, et al. 2019. Cell. 176:897. PubMed
  206. Hoyer FF, et al. 2020. Immunity. 51(5):899-914.e7.. PubMed
  207. Fan HH, et al. 2021. Methods Mol Biol. 2276:203. PubMed
  208. Dye BR, et al. 2020. Biomaterials. 234:119757. PubMed
  209. Bajracharya B, et al. 2022. Biomed Res Int. 2022:9928362. PubMed
  210. Chavkin NW, et al. 2021. J Am Heart Assoc. 10:e019904. PubMed
  211. Bonavita E, et al. 2020. Immunity. 1215:53. PubMed
  212. Zhang L, et al. 2020. Cell. 442:181. PubMed
  213. Sangaletti S, et al. 2021. iScience. 24(6):102510. PubMed
  214. Sheng J, et al. 2021. eLife. 10:00. PubMed
  215. Martins R, et al. 2016. Nat Immunol. 17:1361-1372. PubMed
  216. Kwon H, Kim S 2016. Cell Death Dis. 7:22285. PubMed
  217. Kong P, et al. 2013. Am J Physiol Heart Circ Physiol. 305:1363. PubMed
  218. Fransén Pettersson N, et al. 2018. PLoS One. 13:e0203228. PubMed
  219. Gundra UM, et al. 2017. Nat Immunol. 1.195833333. PubMed
  220. Ramavath NN, et al. 2021. Front Immunol. 12:786680. PubMed
  221. Shue YT, et al. 2022. Nat Commun. 13:2690. PubMed
  222. Spiljar M, et al. 2021. Cell Metab. 33:2231. PubMed
  223. Aguado B, et al. 2015. Sci Rep. 5: 17566. PubMed
  224. Hall JA, et al. 2020. Cell Metabolism. 32(4):665-675.e6. PubMed
  225. Li S, et al. 2017. Applied Materials & Interfaces. 10.1021/acsami.7b03160. PubMed
  226. Sadtler K, et al. 2017. Tissue Eng Part A. 23:1044. PubMed
  227. Petriello MC, et al. 2018. Toxicol Sci. 162:548. PubMed
  228. Liu Z, et al. 2020. STAR Protoc. 1:100029. PubMed
  229. Tham SM, et al. 2021. Biomedicines. 9:. PubMed
  230. Pastor Arroyo EM, et al. 2022. Clin Sci (Lond). 136:557. PubMed
  231. Aggarwal N, et al. 2021. Cell Rep. 37:110170. PubMed
  232. Zhang L, et al. 2021. Mol Ther. 29:744. PubMed
  233. Nabekura T, et al. 2020. Immunity. 96:52. PubMed
  234. Bae S, et al. 2021. Cell Reports. 35(11):109264. PubMed
  235. Harvey RE et al. 2017. Endocrinology. 158(7):2179-2189 . PubMed
  236. Chng S, et al. 2016. Sci Rep. 6: 23820. PubMed
  237. Denis C, et al. 2014. Nucleic Acids Res. 42:7370. PubMed
  238. Yu YR, et al. 2020. STAR Protocols. 11(3):e0150606. PubMed
  239. Riopel M, et al. 2019. Mol Metab. 20:89. PubMed
  240. Youssif C, et al. 2018. EMBO Mol Med. 10:e8403. PubMed
  241. Moriyasu T, et al. 2018. PLoS Negl Trop Dis. 12:e0006197. PubMed
RRID
AB_893478 (BioLegend Cat. No. 123113)
AB_893478 (BioLegend Cat. No. 123114)

Antigen Details

Structure
EGF-TM7 family member, 160 kD glycoprotein
Distribution

Majority of tissue macrophages including peritoneal macrophages, macrophages in lung, gut, thymus and red pulp of spleen, Kupffer cells, Langerhans cells, bone marrow stromal cells, and a subset of dendritic cells

Function
Induction of immunological tolerance
Cell Type
Dendritic cells, Langerhans cells, Macrophages, Tregs
Biology Area
Cell Biology, Immunology, Innate Immunity, Neuroinflammation, Neuroscience
Antigen References

1. Austy JM and Gordon S. 1981. Eur. J. Immunol. 11:805.
2. Hume DA, et al. 1983. J. Exp. Med. 158:1522.
3. Ruedl C, et al. 1996. Eur. J. Immunol. 26:1801.
4. McKnight AJ, et al. 1996. J. Biol. Chem. 271:486.
5. Lin HH, et al. 2005. J. Exp. Med. 201:1615.

Gene ID
13733 View all products for this Gene ID
UniProt
View information about F4/80 on UniProt.org

Other Formats

View All F4/80 Reagents Request Custom Conjugation
Description Clone Applications
Brilliant Violet 605™ anti-mouse F4/80 BM8 FC
Purified anti-mouse F4/80 BM8 FC,IHC,WB
Biotin anti-mouse F4/80 BM8 FC,IHC
FITC anti-mouse F4/80 BM8 FC
PE anti-mouse F4/80 BM8 FC
PE/Cyanine5 anti-mouse F4/80 BM8 FC
PE/Cyanine7 anti-mouse F4/80 BM8 FC
APC anti-mouse F4/80 BM8 FC
APC/Cyanine7 anti-mouse F4/80 BM8 FC
Alexa Fluor® 488 anti-mouse F4/80 BM8 FC,IHC-F,3D IHC
Alexa Fluor® 647 anti-mouse F4/80 BM8 FC,IHC-F,3D IHC
Pacific Blue™ anti-mouse F4/80 BM8 FC
PerCP anti-mouse F4/80 BM8 FC
PerCP/Cyanine5.5 anti-mouse F4/80 BM8 FC
Alexa Fluor® 700 anti-mouse F4/80 BM8 FC
Brilliant Violet 421™ anti-mouse F4/80 BM8 FC,IHC-F,SB
Brilliant Violet 510™ anti-mouse F4/80 BM8 FC
Alexa Fluor® 594 anti-mouse F4/80 BM8 IHC-F
Brilliant Violet 785™ anti-mouse F4/80 BM8 FC
Purified anti-mouse F4/80 (Maxpar® Ready) BM8 FC,CyTOF®
PE/Dazzle™ 594 anti-mouse F4/80 BM8 FC
Brilliant Violet 650™ anti-mouse F4/80 BM8 FC
Brilliant Violet 711™ anti-mouse F4/80 BM8 FC
APC/Fire™ 750 anti-mouse F4/80 BM8 FC
TotalSeq™-A0114 anti-mouse F4/80 BM8 PG
TotalSeq™-B0114 anti-mouse F4/80 BM8 PG
TotalSeq™-C0114 anti-mouse F4/80 BM8 PG
Spark YG™ 570 anti-mouse F4/80 BM8 IHC-F
KIRAVIA Blue 520™ anti-mouse F4/80 BM8 FC
Ultra-LEAF™ Purified anti-mouse F4/80 BM8 FC,IHC,WB
APC/Fire™ 810 anti-mouse F4/80 BM8 FC
Spark NIR™ 685 anti-mouse F4/80 BM8 FC
Spark Blue™ 550 anti-mouse F4/80 BM8 FC
Brilliant Violet 570™ anti-mouse F4/80 BM8 FC
Brilliant Violet 750™ anti-mouse F4/80 BM8 FC
PE/Fire™ 810 anti-mouse F4/80 BM8 FC
Spark Red™ 718 anti-mouse F4/80 (Flexi-Fluor™) BM8 FC
Spark Blue™ 574 anti-mouse F4/80 (Flexi-Fluor™) BM8 FC
Go To Top Version: 2    Revision Date: 10/25/2013

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

BioLegend, the BioLegend logo, and all other trademarks are property of BioLegend, Inc. or their respective owners, and all rights are reserved.

 

8999 BioLegend Way, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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