Purified anti-mouse CD160 Antibody anti-CD160

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Clone: 7H1 (See other available formats)
Regulatory Status: RUO
Other Names: BY55, NK1, NK28
Isotype: Rat IgG2a, κ
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Product Citations: publications

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143002

100 µg

£117

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Description

CD160, also known as BY55, is a 27 kD glycoprotein and member of the Ig superfamily. It is anchored to the cell membrane through glycosylphosphatidylinositol (GPI) and forms disulfide-linked multimers. A soluble form of CD160 is secreted by activated CD8⁺ T cells. Expressed by NK, NKT, γ/δ T cells, intestinal intraepithelial T cells and a subset of memory CD8⁺ T cells, CD160 binds both classical and non-classical MHC class I molecules. It is also a ligand for HVEM. CD160 enhances proliferation of activated CD8⁺ T cells and triggers cell cytotoxicity in NK cells.

Product Details

Technical Data Sheet (pdf)

Product Details

Verified Reactivity: Mouse
Antibody Type: Monoclonal
Host Species: Rat
Immunogen: Soluble His-Tag mouse CD160
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation: The antibody was purified by affinity chromatography.
Concentration: 0.5 mg/ml
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C.
Application: FC - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
RRID: AB_11150583 (BioLegend Cat. No. 143002)

Antigen Details

Structure: Membrane glycoprotein, member of the Ig superfamily, 27 kD, glycosylphosphatidylinositol (GPI)-anchored, forms disulfide-linked multimers on the cell surface
Distribution: NK, NKT, γ/δT cells, intestinal intraepithelial T cells, subset of memory CD8+ T cells
Function: Enhances proliferation of activated CD8+ T cells, triggers cell cytotoxicity in NK cells
Ligand/Receptor: Classical and non-classical MHC-class I molecules, HVEM
Cell Type: NK cells, NKT cells, T cells
Biology Area: Immunology, Innate Immunity, Costimulatory Molecules
Molecular Family: CD Molecules, MHC Antigens, TCRs
Antigen References: 1. Shui JW, et al. 2011. J. Leukoc. Biol. 89:517.
2. Del Rio ML, et al. 2010. J. Leukoc. Biol. 87:223.
3. Cai G and Freeman GJ. 2009. Immunol. Rev. 229:244.
Gene ID: 54215 View all products for this Gene ID
UniProt: View information about CD160 on UniProt.org

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Other Formats

View All CD160 Reagents Request Custom Conjugation

Description	Clone	Applications
Purified anti-mouse CD160	7H1	FC
PE anti-mouse CD160	7H1	FC
PE/Cyanine7 anti-mouse CD160	7H1	FC
PerCP/Cyanine5.5 anti-mouse CD160	7H1	FC
APC anti-mouse CD160	7H1	FC
TotalSeq™-A1006 anti-mouse CD160	7H1	PG
TotalSeq™-C1006 anti-mouse CD160	7H1	PG

Certificate of Analysis

Go To Top Version: 1 Revision Date: 11/30/2012

For Research Use Only. Not for diagnostic or therapeutic use.

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

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