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APC anti-human TCR Vβ8 Antibody

Pricing & Availability
Clone
JR2 (JR.2) (See other available formats)
Regulatory Status
RUO
Other Names
Vbeta8
Isotype
Mouse IgG2b, κ
Ave. Rating
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Product Citations
publications
JR2_APC_TCR_Vbeta8_Antibody_1_101917
Human peripheral blood lymphocytes were stained with CD3 (clone HIT3a) PE and anti-human TCR Vβ8 APC (clone JR2 (JR.2), top) or mouse IgG2b, κ APC isotype control (bottom).
  • JR2_APC_TCR_Vbeta8_Antibody_1_101917
    Human peripheral blood lymphocytes were stained with CD3 (clone HIT3a) PE and anti-human TCR Vβ8 APC (clone JR2 (JR.2), top) or mouse IgG2b, κ APC isotype control (bottom).
  • JR2_APC_TCR_Vbeta8_Antibody_2_101917
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348105 25 tests 105€
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348106 100 tests 218€
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Description

Vβ8 T cell receptor (TCR Vβ8) is a variant of the TCR β chain which is heterodimerized with TCR α chain and expressed on a subset of T cells. In association with CD3 complex, TCR α/β functions recognition of antigen and initiating T cell mediated immune responses. Human Vβ8 has been described as the target of the streptococcal mitogenic exotoxin z (SMEZ) and SMEZ-2.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.

Excitation Laser
Red Laser (633 nm)
Application References
  1. Lavoie PM, et al. 2005. Int. Immunol. 17:931
  2. Okas M, et al. 2010. J. Immunother. 33:96
RRID
AB_2721306 (BioLegend Cat. No. 348105)
AB_2721306 (BioLegend Cat. No. 348106)

Antigen Details

Structure
Immunoglobulin superfamily, associate with TCR Vα chain and CD3 complex
Distribution

Subset of T cells

Function
Antigen recognition
Ligand/Receptor
MHC-Peptide complex
Cell Type
T cells
Biology Area
Adaptive Immunity, Immunology
Molecular Family
TCRs
Antigen References

1. Proft T, et al. 1999. J. Exp. Med. 189:89.
2. Kelsen J, et al. 2004. Scand. J. Gastroenterol. 39:238.

Gene ID
6957 View all products for this Gene ID
UniProt
View information about TCR Vbeta8 on UniProt.org

Related FAQs

There are no FAQs for this product.
Go To Top Version: 0    Revision Date: 10/20/2017

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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