- Clone
- QA19A14 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- Endoglin, Cell surface MJ7/18 antigen, END, Edg, ENG, HHT1, ORW1
- Isotype
- Mouse IgG1, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
Cat # | Size | Price | Quantity Check Availability | Save | ||
---|---|---|---|---|---|---|
366005 | 25 tests | 177€ | ||||
366006 | 100 tests | 348€ |
Endoglin (CD105) is a type I membrane glycoprotein that is part of the TGF beta receptor complex. It is expressed in vascular endothelial tissue as well as a variety of other tissues. Endoglin may also be involved in the cytoskeletal organization affecting cell morphology and migration.
Product DetailsProduct Details
- Verified Reactivity
- Human
- Antibody Type
- Recombinant
- Host Species
- Mouse
- Immunogen
- EDG (CD105) isolated from acute lymphoblastic leukemia cells
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with Brilliant Violet 605™ under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Brilliant Violet 605™ excites at 405 nm and emits at 603 nm. The bandpass filter 610/20 nm is recommended for detection, although filter optimization may be required depending on other fluorophores used. Be sure to verify that your cytometer configuration and software setup are appropriate for detecting this channel. Refer to your instrument manual or manufacturer for support. Brilliant Violet 605™ is a trademark of Sirigen Group Ltd.
Learn more about Brilliant Violet™.
This product is subject to proprietary rights of Sirigen Inc. and is made and sold under license from Sirigen Inc. The purchase of this product conveys to the buyer a non-transferable right to use the purchased product for research purposes only. This product may not be resold or incorporated in any manner into another product for resale. Any use for therapeutics or diagnostics is strictly prohibited. This product is covered by U.S. Patent(s), pending patent applications and foreign equivalents. - Excitation Laser
-
Violet Laser (405 nm)
- RRID
-
AB_3083356 (BioLegend Cat. No. 366005)
AB_3083356 (BioLegend Cat. No. 366006)
Antigen Details
- Cell Type
- Endothelial cells, Hematopoietic stem and progenitors, Macrophages, Mesenchymal Stem Cells, Monocytes
- Biology Area
- Angiogenesis, Cell Biology, Immunology, Stem Cells
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
-
- Li C, et al. 2003. Br J Cancer. 88:1424.
- Sanz-Rodriguez F, et al. 2004. J Biol Chem. 279(31):32858-68.
- Takahashi N, et al. 2001. Clin Cancer Res. 7(3):524-32.
- Seon BK, et al. 1997. Clin Cancer Res. 3(7):1031-44.
- Haruta Y & Seon BK. 1986. Proc Natl Acad Sci U S A. 83: 7898-902.
- Gene ID
- 2022 View all products for this Gene ID
- UniProt
- View information about CD105 on UniProt.org
Related FAQs
Other Formats
View All CD105 Reagents Request Custom ConjugationDescription | Clone | Applications |
---|---|---|
PE anti-human CD105 (Endoglin) Recombinant Antibody | QA19A14 | FC |
Purified anti-human CD105 (Endoglin) Recombinant Antibody | QA19A14 | FC |
Brilliant Violet 605™ anti-human CD105 (Endoglin) Recombinant Antibody | QA19A14 | FC |
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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PE anti-human CD105 (Endoglin) Recombinant Antibody
Human monocytic cell line THP-1 was stained with anti-human ... -
Purified anti-human CD105 (Endoglin) Recombinant Antibody
Human monocytic cell line THP-1 was stained with purified an... -
Brilliant Violet 605™ anti-human CD105 (Endoglin) Recombinant Antibody
Human monocytic cell line THP-1 was stained with anti-human ...
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