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FITC anti-human CD37 Antibody

Pricing & Availability
Clone
M-B371 (See other available formats)
Regulatory Status
RUO
Workshop
V CD37.4
Other Names
Tetraspanin26, tspan-26, GP52-40
Isotype
Mouse IgG1, κ
Ave. Rating
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Product Citations
publications
M-B371_FITC_CD37_Antibody_FC_021113
Human peripheral blood lymphocytes were stained with CD37 (clone M-B371) FITC (filled histogram) or mouse IgG1, κ FITC isotype control (open histogram).
  • M-B371_FITC_CD37_Antibody_FC_021113
    Human peripheral blood lymphocytes were stained with CD37 (clone M-B371) FITC (filled histogram) or mouse IgG1, κ FITC isotype control (open histogram).
Compare all formats See FITC spectral data
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356303 25 tests 100€
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356304 100 tests 202€
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Description

CD37 is a 40-52 kD type II transmembrane protein, also known as tetraspanin-26.  It is a member of the transmembrane tetraspanin family. It can interact with integrins and other transmembrane 4 superfamily members (CD53, CD81, CD82).  CD37 is expressed predominantly on B cells; low expression is detected on T cells and myeloid cells.  No expression is reported on NK cells and plasma cells.  It is involved in regulation of T cell proliferation.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography and conjugated with FITC under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.

Excitation Laser
Blue Laser (488 nm)
Application Notes

Additional reported applications (for the relevant formats) include: immunohistochemical staining of frozen tissue sections1.

Application References
  1. Leshchenko VV. et al. 2010. Blood 116:1025. (FC, IHC)
Product Citations
  1. Silvin A, et al. 2020. Cell. 182:1401. PubMed
  2. Jiang C, et al. 2020. Cell Reports. 28(5):1307-1322.e8.. PubMed
RRID
AB_2561836 (BioLegend Cat. No. 356303)
AB_2561836 (BioLegend Cat. No. 356304)

Antigen Details

Structure
40-52 kD, type II integral membrane protein
Distribution

B cells, weak expression on T cells and myeloid cells

Function
Involved in regulation of T cell proliferation
Ligand/Receptor
α3β1
Cell Type
B cells
Biology Area
Costimulatory Molecules, Immunology
Molecular Family
CD Molecules
Antigen References

1. Moore K, et al. 1987. J. Pathol. 152:13.
2. Schwartz-Albiez R, et al. 1988. J. Immunol. 140:905.

Gene ID
951 View all products for this Gene ID
UniProt
View information about CD37 on UniProt.org
Go To Top Version: 1    Revision Date: 02/13/2013

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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