- Clone
- S15042I (See other available formats)
- Regulatory Status
- RUO
- Other Names
- BOB, Brother of Bonzo , G protein-coupled receptor 15, 4933439K08Rik
- Isotype
- Rat IgG2a, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
Cat # | Size | Price | Quantity Check Availability | Save | ||
---|---|---|---|---|---|---|
154603 | 25 µg | 123€ | ||||
154604 | 100 µg | 268€ |
GPR15, also known as BOB, is a G-protein coupled receptor with 7 transmembrane regions that is present on the cell surface as a homotrimer. Its ligand, GPR15L, was recently identified. GPR15 is expressed by effector T cells and subsets of memory T cells, and is involved in the recruitment of proinflammatory CD4+ T cells responsible of the pathogenesis in colitis. In humans, GPR15 acts as a receptor for human immunodeficiency virus (HIV) type 1 and 2, and is upregulated on monocytes and neutrophils in the synovia of patients with RA.
Product DetailsProduct Details
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- Mouse GPR15-Transfectants
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
- Concentration
- 0.2 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
-
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- RRID
-
AB_2728215 (BioLegend Cat. No. 154603)
AB_2728215 (BioLegend Cat. No. 154604)
Antigen Details
- Structure
- G-protein coupled receptor
- Distribution
-
Effector and memory T cells
- Function
- Probable chemokine receptor, signal transduction
- Cell Type
- T cells, Tregs
- Biology Area
- Immunology
- Antigen References
-
- Nguyen L, et al. 2015. Nature Immunology. 16:207
- Kiene M, et al. 2014. PLoS. One. 9:e88195
- Cartwright A, et al. 2014. Cytokine. 67:53
- Kim SV, et al. 2013. Science. 340:1456
- Okamoto Y, et al. 2013. J. Biol. Chem. 288:9189
- Gene ID
- 71223 View all products for this Gene ID
- UniProt
- View information about GPR15/BOB on UniProt.org
Related Pages & Pathways
Pages
Related FAQs
- What type of PE do you use in your conjugates?
- We use R-PE in our conjugates.
Other Formats
View All GPR15/BOB Reagents Request Custom ConjugationDescription | Clone | Applications |
---|---|---|
Purified anti-mouse GPR15/BOB | S15042I | FC |
PE anti-mouse GPR15/BOB | S15042I | FC |
APC anti-mouse GPR15/BOB | S15042I | FC |
PE/Cyanine7 anti-mouse GPR15/BOB | S15042I | FC |
PE/Dazzle™ 594 anti-mouse GPR15/BOB | S15042I | FC |
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Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
-
Purified anti-mouse GPR15/BOB
BALB/c splenocytes were stained with purified anti-mouse GPR... Mouse GPR15/BOB transfected Ba/F3 cell line was stained with... -
PE anti-mouse GPR15/BOB
BALB/c splenocytes were stained with CD4 APC and PE anti-mou... Mouse GPR15/BOB transfected Ba/F3 cell line was stained with... -
APC anti-mouse GPR15/BOB
BALB/c splenocytes were stained with CD3 FITC and anti-mouse... -
PE/Cyanine7 anti-mouse GPR15/BOB
C57BL/6 splenocytes were stained with anti-mouse CD3 APC and... -
PE/Dazzle™ 594 anti-mouse GPR15/BOB
C57BL/6 splenocytes were stained with anti-mouse CD3 APC and...
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