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Purified anti-CD66e Antibody

Pricing & Availability
Clone
BSB-13 (See other available formats)
Regulatory Status
RUO
Other Names
Carcinoembryonic antigen, CEA, CEACAM5, CD66 antigen, CD66e
Isotype
Mouse IgG1, κ
Ave. Rating
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Product Citations
publications
BSBdash13_PURE_CD66e_Antibody_IHCP_072216
IHC staining of anti-CD66e antibody (clone BSB-13) on formalin-fixed paraffin-embedded human colon tissue. Following antigen retrieval using sodium citrate, the tissue was incubated with the primary antibody for 60 minutes at room temperature at 1 µg/mL. BioLegend's Ultra Streptavidin (USA) HRP Detection Kit was used for detection, followed by counterstaining with hematoxylin.
  • BSBdash13_PURE_CD66e_Antibody_IHCP_072216
    IHC staining of anti-CD66e antibody (clone BSB-13) on formalin-fixed paraffin-embedded human colon tissue. Following antigen retrieval using sodium citrate, the tissue was incubated with the primary antibody for 60 minutes at room temperature at 1 µg/mL. BioLegend's Ultra Streptavidin (USA) HRP Detection Kit was used for detection, followed by counterstaining with hematoxylin.
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847002 100 µg 240€
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Description

Carcinoembryonic antigen (CEA), also known as CD66e, is a glycoprotein involved in cell adhesion and intracellular signaling. It is normally produced during fetal development in the gut, and its production stops before birth. CEA is re-expressed in increased amounts in Intestinal Carcinomas and several other tumors.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Recombinant human CEA.
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

IHC-P - Quality tested
IHC-F, WB - Reported in the literature, not verified in house
Recommended Usage

Each lot of this antibody is quality control tested by formalin-fixed paraffin-embedded immunohistochemical staining. For immunohistochemistry, a concentration range of 0.5 - 1.0 µg/ml is suggested. It is recommended that the reagent be titrated for optimal performance for each application.

RRID
AB_2629664 (BioLegend Cat. No. 847002)

Antigen Details

Structure
CEA is a 702 amino acid protein with a molecular mass of 77 kD.
Distribution

Tissue distribution: intestine, colon, and blood.
Cellular distribution: extracellular and plasma membrane.

Function
CEA is a biomarker for gastrointestinal cancers and may promote tumor development through its role as an adhesion molecule.
Biology Area
Cell Adhesion, Cell Biology
Antigen References

1. Go VL. 1976. Cancer. 37:562. PubMed
2. DeLellis RA, et al. 1978. Am. J. Clin. Pathol. 70:587. PubMed
3. Kamino H, et al. 1988. Cancer. 61:1142. PubMed
4. Tron V, et al. 1987. Arch. Pathol. Lab. Med. 111:291. PubMed

Gene ID
1048 View all products for this Gene ID
UniProt
View information about CD66e on UniProt.org
Go To Top Version: 2    Revision Date: 01/30/2017

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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