- Clone
- 4F3-A8-D9 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- Transducin Beta Like 1 X-Linked Receptor 1, F-Box-Like/WD Repeat-Containing Protein TBL1XR1, Transducin Beta-Like 1X-Related Protein 1, MRD41, DC42
- Isotype
- Mouse IgG1, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
Cat # | Size | Price | Quantity Check Availability | Save | ||
---|---|---|---|---|---|---|
870001 | 25 µg | 85€ | ||||
870002 | 100 µg | 221€ |
TBLR1 is a member of the WD40 repeat-containing family of proteins. It shares similarity with TBL1 in sequence, and is believed to be a component of the complex of nuclear corepressor and HDAC3. TBLR1 is involved in signaling pathway during development through the regulation of chromatin acetylation. It is also associated with diseases including pierpont syndrome, mental retardation, and autism spectrum disorders.
Product DetailsProduct Details
- Verified Reactivity
- Mouse, Rat
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Purified recombinant human TBLR1 protein fragments expressed in E. coli
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
WB - Quality tested
IHC-P - Verified - Recommended Usage
-
Each lot of this antibody is quality control tested by western blotting. For western blotting, the suggested use of this reagent is 0.2 - 0.5 µg/mL. For immunohistochemistry on formalin-fixed paraffin-embedded tissue sections, a concentration range of 5.0 - 10 µg/mL is suggested. It is recommended that the reagent be titrated for optimal performance for each application.
- RRID
-
AB_2820184 (BioLegend Cat. No. 870001)
AB_2820184 (BioLegend Cat. No. 870002)
Antigen Details
- Structure
- TBLR1 is a 514 amino acid protein with a predicted and observed molecular mass of ~56 kD.
- Distribution
-
Tissue Distribution: Brain, immune system, heart, and lung
Cellular Distribution: Nucleus - Function
- Chromatin acetylation
- Interaction
- HDAC3, TBL1, NCOR1, NCOR2, MECP2
- Cell Type
- B cells, Monocytes, Neurons, NK cells
- Biology Area
- Cancer Biomarkers, Cell Biology, Neurodegeneration, Neuroscience, Signal Transduction
- Molecular Family
- Nuclear Markers
- Antigen References
-
- Xi X, et al. 2019. Eur J Pharmacol. 844:259-267.
- Nishi A, et al. 2017. Sci Rep. 7(1):2887.
- Gene ID
- 81004 View all products for this Gene ID 365755 View all products for this Gene ID
- UniProt
- View information about TBLR1 on UniProt.org
Related FAQs
Other Formats
View All TBLR1 Reagents Request Custom ConjugationDescription | Clone | Applications |
---|---|---|
Purified anti-TBLR1 | 4F3-A8-D9 | WB,IHC-P |
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
Follow Us