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Purified anti-Tubulin β 3 (TUBB3) Antibody (Previously Covance catalog# MMS-435P)

Pricing & Availability
Clone
TUJ1 (See other available formats)
Regulatory Status
RUO
Other Names
CDCBM, CDCBM1, CFEOM3, CFEOM3A, FEOM3, TUBB4, Tubulin beta-3 chain, tubulin beta-III, tubulin beta-4 chain, class III beta-tubulin
Previously
Covance Catalog# MMS-435P
Isotype
Mouse IgG2a, κ
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Product Citations
publications
A_TUJ1_PURE_Tubulin-beta3_IHCP_Hu_011618
IHC staining of purified anti-Tubulin β 3 (TUBB3) antibody (clone TUJ1) on formalin-fixed paraffin-embedded human brain tissue. Following antigen retrieval using Sodium Citrate H.I.E.R., the tissue was incubated with 1 µg/mL of the primary antibody overnight at 4°C. BioLegend’s Ultra Streptavidin (USA) HRP Detection Kit (Multi-Species, DAB, Cat. No. 929901) was used for detection followed by hematoxylin counterstaining, according to the protocol provided. The image was captured with a 40X objective.
  • A_TUJ1_PURE_Tubulin-beta3_IHCP_Hu_011618
    IHC staining of purified anti-Tubulin β 3 (TUBB3) antibody (clone TUJ1) on formalin-fixed paraffin-embedded human brain tissue. Following antigen retrieval using Sodium Citrate H.I.E.R., the tissue was incubated with 1 µg/mL of the primary antibody overnight at 4°C. BioLegend’s Ultra Streptavidin (USA) HRP Detection Kit (Multi-Species, DAB, Cat. No. 929901) was used for detection followed by hematoxylin counterstaining, according to the protocol provided. The image was captured with a 40X objective.
  • B_TUJ1_PURE_Tubulin-beta3_IHCP_Rat_011618
    IHC staining of purified anti-Tubulin β 3 (TUBB3) antibody (clone TUJ1) on formalin-fixed paraffin-embedded rat brain tissue. Following antigen retrieval using Sodium Citrate H.I.E.R., the tissue was incubated with 0.5 µg/mL of the primary antibody overnight at 4°C. BioLegend’s Ultra Streptavidin (USA) HRP Detection Kit (Multi-Species, DAB, Cat. No. 929901) was used for detection followed by hematoxylin counterstaining, according to the protocol provided. The image was captured with a 40X objective.
  • C_TUJ1_PURE_Tubulin-beta3_WB_011618
    Western blot of purified anti-Tubulin β 3 (TUBB3) antibody (clone TUJ1). Lane 1: Molecular weight marker; Lane 2: 20 µg of human brain lysate; Lane 3: 20 µg of Mouse brain lysate; Lane 4: 20 µg of rat brain lysate. The blots were incubated with 1 ug/mL of TUJ1 or mouse IgG overnight at 4°C, followed by incubation with HRP-labeled goat anti-mouse IgG (Cat. No. 405306). Enhanced chemiluminescence was used as the detection system.
  • D_TUJ1_PURE_Tubulin-beta3_ICC_011618
    ICC staining of purified anti-Tubulin β 3 (TUBB3) antibody (clone TUJ1) on SH-SY5Y neuroblastoma cells. The cells were fixed by 4% PFA, permeabilized with a buffer containing 0.1% Triton X-100 and 0.25% BSA, and blocked with 2% Normal Goat Serum and 0.02% BSA. The cells were then incubated with 1 µg/mL of the primary antibody for 3 hours at room temperature, followed by incubation with 0.5 µg/mL Alexa Fluor® 594 goat anti-mouse IgG (Cat. No. 405326) for 1 hour at room temperature. Nuclei were counterstained with DAPI. The image was captured with a 60X objective Scale bar: 20 µm
  • E_Ankita_Patil
    Methanol fixed superior cervical ganglion neurons were stained with anti-tubulin β3 (pink) and anti-TRIM46 (aqua), then stained with secondary antibodies, phalloidin (orange) and DAPI (blue). Image generously submitted to the 2017 Cell Life Imaging Competition by Ankita Patil from Drexel University.
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801213 25 µL 85€
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801201 100 µL 212€
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801202 250 µL 313€
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Description

Tubulin is the main component of microtubules. In adults, tubulin beta 3 (TUBB3) is primarily expressed in neurons and is commonly used as a neuronal marker. It plays an important role in neuronal cell proliferation and differentiation. Mutations in this gene cause congenital fibrosis of the type 3 extraocular muscles. Tubulin beta 3 (TUBB3) is also found in a wide range of tumors. Studies indicate that it is a predictive and prognostic marker in various tumors.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Human, Mouse, Rat
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
This antibody was raised against microtubules derived from rat brain.
Formulation
Phosphate-buffered solution + 0.03% Thimerosal.
Preparation
The antibody was purified by affinity chromatography.
Concentration
1.0 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C. Please note the storage condition for this antibody has been changed from -20°C to between 2°C and 8°C. You can also check your vial or your CoA to find the most accurate storage condition for this antibody.
Application

IHC-P - Quality tested
WB, ICC - Verified
FC - Reported in the literature, not verified in house
SB - Community verified
Recommended Usage

Each lot of this antibody is quality control tested by formalin-fixed paraffin-embedded immunohistochemical staining. For immunohistochemistry, a concentration range of 1.0 - 5.0 µg/ml is suggested. For Western blotting, the suggested use of this reagent is 1.0 - 5.0 µg/ml. For immunocytochemistry, a concentration range of 1.0 - 5.0 μg/ml is recommended. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

Additional reported applications (for the relevant formats) include: flow cytometry4, immunofluorescence microscopy1-5,7, immunohistochemistry5,7, Western blotting8, and spatial biology (IBEX)9,10.

This antibody is well characterized and highly reactive to neuron specific Class III ß-tubulin (ßIII). TUJ1 does not identify ß-tubulin found in glial cells. TUJ1 recognizes an epitope located within the last 15 C-terminal residues8.

Additional Product Notes

This product has been verified for IHC-F (Immunohistochemistry - frozen tissue sections) on the NanoString GeoMx® Digital Spatial Profiler. The GeoMx® enables researchers to perform spatial analysis of protein and RNA targets in FFPE and fresh frozen human and mouse samples. For more information about our spatial biology products and the GeoMx® platform, please visit our spatial biology page.

Application References
  1. Nishimura K, et al. 2017. PLoS One. 12(1): e0170568. (ICC)
  2. Jongbloets J, et al. 2017. Nat Commun. 8: 14666. (ICC) PubMed
  3. Liu W.J, et al. 2015. Eur J Histochem. 59(1): 2464. (ICC) PubMed
  4. Chintalapudi SR, et al. 2016. Front Aging Neursci. 8:93. (FC, ICC) PubMed
  5. Ambasudhan R, et al. 2011. Cell Stem Cell. 9(2):113. (IHC, ICC)
  6. Hu X., et al. 2006. Nature Neuroscicene. 9(12):1520. (WB) PubMed
  7. Zechner D., et al. 2003. Develop Biology. 258(2):406. (ICC, IHC)
  8. Lee MK, et al. 1990. Proc. Natl. Acad. Sci. USA 18:7195. (WB)
  9. Radtke AJ, et al. 2020. Proc Natl Acad Sci USA. 117:33455-33465. (SB) PubMed
  10. Radtke AJ, et al. 2022. Nat Protoc. 17:378-401. (SB) PubMed
Product Citations
  1. Boyer NP, et al. 2018. Eneuro. 55:1847. PubMed
  2. Lee SW et al. 2018. Developmental cell. 46(1):73-84 . PubMed
  3. Chia PH et al. 2018. eLife. 7 pii: e32451. PubMed
  4. Erwig MS, et al. 2019. Elife. 8:. PubMed
  5. Tohgi N, et al. 2017. Cell Cycle. 16:95. PubMed
  6. Nicole O, et al. 2018. Mol Psychiatry. 23:2209. PubMed
  7. Kirihara T, et al. 2019. iScience. 14:301. PubMed
  8. Sanli I, et al. 2018. Cell Rep. 23:337. PubMed
  9. Croteau LP, et al. 2019. Sci Rep. 9:12009. PubMed
  10. Ioannou MS et al. 2019. Cell. 177(6):1522-1535 . PubMed
  11. Paonessa F et al. 2019. Cell reports. 26(3):582-593 . PubMed
  12. de la Cerda B et al. 2019. Stem cell research. 1726:26:00 . PubMed
  13. García‐Peña CM et al. 2018. Frontiers in neuroanatomy. 0.566666667 . PubMed
  14. Coleman JH, et al. 2017. J Comp Neurol. 525:3391. PubMed
  15. Abud EM et al. 2017. Neuron. 94(2):278-293 . PubMed
  16. Huang YA et al. 2017. Cell. 168(3):427-441 . PubMed
  17. Hegarty DM, et al. 2018. Pain Rep. 3:e664. PubMed
  18. Dai WJ, et al. 2019. Evid Based Complement Alternat Med. 2019:8413576. PubMed
  19. Wang XW, et al. 2020. Cell Rep. 31:107537. PubMed
  20. Woeste MA, et al. 2019. J Biol Chem. 294:3853. PubMed
  21. Tian R, et al. 2019. Neuron. 104:239. PubMed
  22. Gai M, et al. 2016. EMBO Rep. 17: 1396 - 1409. PubMed
  23. Nonomura K, et al. 2016. Nature. 541:176-181. PubMed
  24. Ueki J, et al. 2017. Sci Rep. 7:42522. PubMed
  25. Fernandes HJR, et al. 2020. Cell Rep. 33:108263. PubMed
  26. Ko KW, et al. 2020. J Cell Biol. 219:00:00. PubMed
  27. Tilak M, et al. 2021. Molecular Cancer Research. 19(5):757-770. PubMed
  28. Alonso-Barroso E, et al. 2017. Stem Cell Research. 23:173-177. PubMed
  29. Wang YL, et al. 2021. Cell Reports. 36(8):109537. PubMed
  30. Tristan CA, et al. 2020. bioRxiv. . PubMed
  31. Abey A, et al. 2020. Brain Pathol. 31:144. PubMed
  32. Birsa N, et al. 2021. Sci Adv. 7: . PubMed
  33. Castelli LM, et al. 2021. Mol Neurodegener. 16:53. PubMed
  34. Nakayama T, et al. 2021. Cell Rep Med. 2:100421. PubMed
  35. Ye M, et al. 2021. Cell Death Dis. 12:1149. PubMed
  36. Seebauer L, et al. 2022. Int J Mol Sci. 23:. PubMed
  37. Zainul Z, et al. 2022. Sci Rep. 12:3344. PubMed
  38. Ahangari N, et al. 2021. J Neuropathol Exp Neurol. 80:944. PubMed
  39. Dang LT, et al. 2021. Dev Neurobiol. 81:696. PubMed
  40. Tsefou E, et al. 2021. Biochem J. 478:4099. PubMed
  41. Jacquier A, et al. 2022. Acta Neuropathol. 144:707. PubMed
  42. Wang Z, et al. 2022. Research (Wash D C). 2022:9832128. PubMed
  43. Schroeter MS, et al. 2022. MRS Bull. 47:530. PubMed
  44. Lee J, et al. 2022. Nat Protoc. 17:1266. PubMed
  45. Piermarini E, et al. 2022. Hum Mol Genet. 31:1844. PubMed
  46. Sun X, et al. 2022. Dev Cell. 57:112. PubMed
  47. Grigor'eva EV 2021. Stem Cell Research. 59:102651. PubMed
  48. Muralidharan H, et al. 2022. J Neurosci. 42:2149. PubMed
  49. Zhang A, et al. 2022. EMBO J. 41:e109187. PubMed
  50. Clements RT 2022. eneuro. 9(2). PubMed
  51. Sosnowski P, et al. 2022. Pharmaceuticals (Basel). 15: . PubMed
  52. Hallacli E, et al. 2022. Cell. 185:2035. PubMed
  53. Lin L, et al. 2022. J Comp Neurol. 530:2820. PubMed
  54. Park SY, et al. 2022. Int J Mol Sci. 23: . PubMed
  55. Hoye ML, et al. 2022. Elife. 11: . PubMed
  56. Wu X, et al. 2022. Cell Rep. 40:111085. PubMed
  57. Januel C, et al. 2022. Cell Mol Life Sci. 79:441. PubMed
  58. Frederico B, et al. 2022. Dev Cell. 57:1957. PubMed
  59. Xu J, et al. 2022. Small. 18:e2203431. PubMed
  60. Fleck JS, et al. 2022. Nature. :. PubMed
  61. Liu S, et al. 2023. CNS Neurosci Ther. 29:228. PubMed
  62. Radwitz J, et al. 2022. Cell Mol Life Sci. 79:575. PubMed
  63. Krasnova OA, et al. 2022. Int J Mol Sci. 23: . PubMed
  64. Vrathasha V, et al. 2022. iScience. 25:105308. PubMed
  65. Liu C, et al. 2022. Cell Mol Life Sci. 79:596. PubMed
  66. Koizumi M, et al. 2022. FASEB J. 36:e22662. PubMed
  67. Herdy JR 2022. Cell Stem Cell. 29(12):1637-1652.e6. PubMed
  68. Zhou Z, et al. 2023. Biol Pharm Bull. 46:102. PubMed
  69. Santiago-Mujika E, et al. 2023. J Alzheimers Dis Rep. 6:739. PubMed
  70. Xue W, et al. 2023. iScience. 26:105898. PubMed
  71. Jin S, et al. 2023. iScience. 26:105885. PubMed
  72. Day C, et al. 2023. Pharmaceuticals (Basel). 16: . PubMed
  73. Willumsen N, et al. 2023. Brain Commun. 5:fcac321. PubMed
  74. Choi EB, et al. 2023. J Biol Chem. 299:102996. PubMed
  75. Ma Y, et al. 2023. Eneuro. 10: . PubMed
  76. Wu W, et al. 2021. Nature. 593:440. PubMed
  77. Le Floch P, et al. 2022. Adv Mater. 34:e2106829. PubMed
  78. Alonso-Alonso S, et al. 2022. Reprod Fertil Dev. 34:576. PubMed
  79. Marrone L, et al. 2022. Hum Mol Genet. 31:2693. PubMed
  80. Hamrangsekachaee M, et al. 2022. ACS Appl Bio Mater. 5:2176. PubMed
  81. Urbaniak A, et al. 2022. Biomed Pharmacother. 153:113440. PubMed
  82. Dong C, et al. 2022. J Neurosci. 42:8373. PubMed
  83. Krasniewski LK, et al. 2022. Elife. 11:. PubMed
  84. Baek J, et al. 2022. Biomater Sci. 10:6768. PubMed
  85. Li TL, et al. 2022. Biomaterials. 290:121825. PubMed
  86. Cattelani C, et al. 2022. Int J Mol Sci. 23:. PubMed
  87. Chen WJ, et al. 2022. Adv Sci (Weinh). :e2205451. PubMed
  88. Wu J, et al. 2022. Methods Mol Biol. 2593:245. PubMed
  89. Whye D, et al. 2023. Curr Protoc. 3:e641. PubMed
  90. Dong Z, et al. 2023. J Biol Chem. 299:103020. PubMed
  91. Campbell B, et al. 2023. Sci Rep. 13:3000. PubMed
  92. Loan A, et al. 2023. iScience. 26:106093. PubMed
  93. Jimenez-Moreno N, et al. 2023. J Cell Biol. 222:. PubMed
  94. Panzi C, et al. 2023. Toxicon. 228:107110. PubMed
  95. Cossec JC, et al. 2023. Cell Rep. 42:112380. PubMed
  96. Eigenhuis KN, et al. 2023. Front Cell Neurosci. 17:1114420. PubMed
  97. Gilbert-Jaramillo J, et al. 2023. Biol Open. 12:. PubMed
  98. Sim KY, et al. 2023. Sci Rep. 13:6864. PubMed
  99. D'aes T, et al. 2023. Int J Mol Sci. 24:. PubMed
  100. Dawicki-McKenna JM, et al. 2023. Nat Commun. 14:2628. PubMed
  101. Paranjape N, et al. 2023. Sci Rep. 13:7689. PubMed
  102. Nguyen TTM, et al. 2023. iScience. 26:106674. PubMed
  103. Georgelou K, et al. 2023. Biomedicines. 11:. PubMed
  104. Kerkering J, et al. 2023. J Clin Invest. . PubMed
  105. Liang MZ, et al. 2023. Cell Biosci. 13:96. PubMed
  106. Lin CY, et al. 2023. J Food Drug Anal. 31:32. PubMed
  107. Martínez-Torres S, et al. 2023. iScience. 26:106814. PubMed
  108. Dos Santos BL, et al. 2023. Pharmaceutics. 15:. PubMed
  109. Stajkovic N, et al. 2023. J Cell Sci. . PubMed
  110. Drobny S, et al. 2023. Transl Neurodegener. 12:31. PubMed
  111. Zhang M, et al. 2023. Neurosci Bull. . PubMed
  112. Babetto E, et al. 2020. Nat Neurosci. 23:1215. PubMed
  113. Eltahir MK, et al. 2022. PLoS One. 17:e0269683. PubMed
  114. Simoes S, et al. 2021. Cell Rep. 37:110182. PubMed
  115. Viais R, et al. 2021. Elife. 10:. PubMed
  116. Lafarga V, et al. 2021. EMBO J. 40:e103311. PubMed
  117. Kim S, et al. 2021. Nat Commun. 12:1807. PubMed
  118. Brown AL, et al. 2022. Nature. 603:131. PubMed
  119. Ruden JB, et al. 2021. Front Mol Neurosci. 14:777049. PubMed
  120. Tseng JH, et al. 2021. Cell Rep. 35:109037. PubMed
  121. Guo B, et al. 2021. Front Cell Dev Biol. 9:768970. PubMed
  122. Li F, et al. 2021. Nat Commun. 12:3845. PubMed
  123. Xia F, et al. 2021. Acta Neuropathol Commun. 51:9. PubMed
  124. Shin BC, et al. 2021. Experimental Neurology. 338:113603. PubMed
  125. Wang D, et al. 2020. Journal of Biological Chemistry. 295(25):8374-8386. PubMed
  126. Khoa LTP, et al. 2020. Cell Stem Cell. 27(3):441-458.e10. PubMed
  127. Domènech EB, et al. 2020. Invest Ophthalmol Vis Sci. 61:14:00. PubMed
  128. Elhardt C, et al. 2020. Transl Vis Sci Technol. 9:06. PubMed
  129. Lee SE, et al. 2020. Cell Death Dis. 1.19375. PubMed
  130. Orozco-Díaz R, et al. 2019. PLoS One. 14:e0220393. PubMed
  131. Arber C, et al. 2019. Brain Commun. 1:fcz024. PubMed
  132. Valès S, et al. 2019. EBioMedicine. 49:172. PubMed
  133. Teissier A, et al. 2019. Mol Psychiatry. :. PubMed
  134. Macova I, et al. 2019. J Neurosci. 39:984. PubMed
  135. Inoue SI, et al. 2017. Hum Mol Genet. 26:4715. PubMed
  136. Shepherd DJ et al. 2017. Journal of neuropathology and experimental neurology. 76(8):683-696 . PubMed
  137. Kow Essuman et al. 2017. Neuron. 93(6):1334-1343 . PubMed
  138. Mangold CA et al. 2018. J Neurochem. 144(6):723-735 . PubMed
  139. Levin E et al. 2019. Cell reports. 26(4):1021-1032 . PubMed
  140. Murcia-Belmonte V, et al. 2019. Curr Biol. 29:1149. PubMed
  141. Daoutsali E et al. 2019. Stem Cell Res. 1723:19:00 . PubMed
  142. Ogawa Y et al. 2019. Neurosci Res. pii: S0168-0102(19)30120-8 . PubMed
  143. Tiethof AK, et al. 2018. Toxics. 6:52. PubMed
  144. Boso D, et al. 2019. Theranostics. 9:4860. PubMed
  145. Cha HL, et al. 2019. Mol Brain. 12:57. PubMed
  146. Wang G et al. 2019. eLife. 8 pii: e38730. PubMed
  147. Vinci M, et al. 2018. Nat Med. 24:1204. PubMed
  148. Laussu J, et al. 2017. Neural Dev. 12:10. PubMed
  149. Hu X, et al. 2019. Stem Cell Reports. 12:290. PubMed
  150. Valadas JS et al. 2018. Neuron. 98(6):1155-1169 . PubMed
  151. Ziller MJ, et al. 2018. Cell Stem Cell. 1.304861111. PubMed
  152. Park SY, et al. 2018. Mol Brain. 169:91. PubMed
  153. Coste C, et al. 2017. PLoS One. 10.1371/journal.pone.0177962. PubMed
  154. Miranda AM, et al. 2018. Nat Commun. 9:291. PubMed
  155. Liu C, et al. 2018. Stem Cell Reports. 4:43. PubMed
  156. Lee SY et al. 2018. Stem cell research. 30:145-149 . PubMed
  157. Vitali I et al. 2018. Cell. 174(5):1264-1276 . PubMed
  158. Roselló-Busquets C, et al. 2019. Front Cell Neurosci. 13:40. PubMed
  159. Stepp MA, et al. 2018. Int J Mol Sci. 19:12. PubMed
  160. Miltner AM, et al. 2019. Int J Mol Sci. 20. PubMed
  161. Canali G, et al. 2018. Hum Mol Genet. 27:1941. PubMed
  162. Haverfield JT, et al. 2017. Reprod Fertil Dev. 29:609. PubMed
  163. Arellano‐Viera E et al. 2019. Stem cell research. 1726:10:00 . PubMed
  164. Ribic A et al. 2019. Cell reports. 26(2):381-393 . PubMed
  165. Varga E et al. 2017. Stem cell research. 25:30-33 . PubMed
  166. Nguyen HX et al. 2014. The Journal of comparative neurology. 522(12):2767-83 . PubMed
  167. Bonnefont J, et al. 2019. Neuron. 103:1096. PubMed
  168. Giandomenico SL, et al. 2019. Nat Neurosci. 22:669. PubMed
  169. Stratton JA, et al. 2020. Front Aging Neurosci. 0.620833333. PubMed
  170. Kishi N, et al. 2016. Nat Commun. 7:10520. PubMed
  171. Nawaz M, et al. 2016. PLoS One. 11: 0148634. PubMed
  172. Tao W, et al. 2020. EMBO Mol Med. 12:e12291. PubMed
  173. Bae B, et al. 2020. RNA. 26:1414. PubMed
  174. Halikere A, et al. 2020. Mol Psychiatry. 25:1406. PubMed
  175. Song JM, et al. 2021. The Journal of Neuroscience. 41(11):2344-2359. PubMed
  176. Benito-Kwiecinski S, et al. 2021. Cell. 184(8):2084-2102.e19. PubMed
  177. Bayerl J, et al. 2021. Cell Stem Cell. . PubMed
  178. Eriksen AZ, et al. 2021. Cell Stem Cell. 28(7):1205-1220.e7. PubMed
  179. Elsayed AK, et al. 2021. Stem Cell Research. 54:102433. PubMed
  180. Lpez-Mrquez A, et al. 2019. Stem Cell Research. 38:101469. PubMed
  181. Sood S, et al. 2020. Proc Natl Acad Sci U S A. 22331:117. PubMed
  182. Lim SH, et al. 2020. J Cell Sci. :133. PubMed
  183. Yun T, et al. 2021. Cell Death Discov. 7:257. PubMed
  184. Herbst WA, et al. 2021. J Cell Biol. 220:. PubMed
  185. Heinrich A, et al. 2021. Cell Rep. 37:109885. PubMed
  186. Earley AM, et al. 2021. Sci Rep. 11:22257. PubMed
  187. Ramirez S, et al. 2021. STAR Protoc. 2:100987. PubMed
  188. Valenzuela M, et al. 2022. Stem Cell Res Ther. 13:261. PubMed
  189. Richardson RT, et al. 2021. Sci Rep. 11:11229. PubMed
  190. Guo X, et al. 2021. Cell. 184:4299. PubMed
  191. Vilallongue N, et al. 2022. Nat Commun. 13:6040. PubMed
  192. Masumoto K, et al. 2022. Sci Rep. 12:10351. PubMed
  193. McClellan S, et al. 2021. Invest Ophthalmol Vis Sci. 62:14. PubMed
  194. Hagihara H, et al. 2021. Cell Rep. 37:109820. PubMed
  195. Boussaad I, et al. 2021. Sci Rep. 11:1439. PubMed
  196. Savino E, et al. 2021. Cells. 10:. PubMed
  197. Liu X, et al. 2021. Cell Prolif. 54:e13124. PubMed
  198. Doron-Mandel E, et al. 2021. EMBO J. 40:e107158. PubMed
  199. Lennox AL, et al. 2020. Neuron. 404:106. PubMed
  200. Pecori F, et al. 2021. Cell Reports. 36(2):109361. PubMed
  201. Aarts CEM, et al. 2021. Stem Cell Research. 54:102444. PubMed
  202. Zhang K, et al. 2021. Neuron. 109(12):1949-1962.e6. PubMed
  203. Aprigliano R, et al. 2021. Cell Reports Medicine. 2(4):100240. PubMed
  204. Pantier R, et al. 2021. Molecular Cell. 81(4):845-858.e8. PubMed
  205. Parlanti P, et al. 2020. Exp Eye Res. 194:107998. PubMed
  206. Toma JS, et al. 2020. Eneuro. 7:00. PubMed
  207. Solis-Castro OO, et al. 2020. Stem Cells Transl Med. 1.390277778. PubMed
  208. Ucuncu E, et al. 2020. Nat Commun. 4.685416667. PubMed
  209. LI Y, et al. 2017. Proc Natl Acad Sci U S A. 114(2):E209-E218. PubMed
  210. Jiang G, et al. 2016. Stem Cells Trans Med. 5(12):1595-1606. PubMed
  211. Martin C, et al. 2016. Genes Dev. 30: 2158 - 2172. PubMed
  212. Kida H, et al. 2016. Cereb Cortex. 10.1093/cercor/bhw134. PubMed
  213. Savino E, et al. 2020. Cell Death Dis. 1.052777778. PubMed
  214. Saito K, et al. 2019. Cell Rep. 29:1555. PubMed
  215. Lilian SJ, et al. 2019. J Assoc Res Otolaryngol. 20:133. PubMed
  216. Milbreta U, et al. 2019. Mol Ther. 27:411. PubMed
  217. Arai Y, et al. 2019. Cell Rep. 29:645. PubMed
  218. Bucan V, et al. 2019. Int J Mol Med. 43:593. PubMed
  219. Petkovich DA et al. 2017. Cell metabolism. 25(4):954-960 . PubMed
  220. Auboyer L et al. 2019. Stem Cell Res. 1727:38:00 . PubMed
  221. Tomassoni–Ardori F, et al. 2019. Elife. 8:e46677. PubMed
  222. Van Der Raadt J, et al. 2019. Nucleic Acids Res. 47:5587. PubMed
  223. Raspa A, et al. 2019. CNS Neurosci Ther. 25:86. PubMed
  224. González C, et al. 2018. Mol Psychiatry. 23:2363. PubMed
  225. Liu H, et al. 2019. Front Cell Neurosci. 13:60. PubMed
  226. Mura M et al. 2018. Stem cell research. 29:170-173 . PubMed
  227. Hermanto Y et al. 2018. Journal of neuroscience research. 96(5):863-874 . PubMed
  228. Playne R, et al. 2018. J Stem Cells Regen Med. 7:e36998. PubMed
  229. Allende ML, et al. 2018. J Lipid Res. 59:550. PubMed
  230. Janssens S, et al. 2018. mSystems. 3. PubMed
  231. Thomas RA et al. 2018. eNeuro. 5(4) pii: ENEURO. PubMed
  232. Tripathy R, et al. 2018. Neuron. 100:1354. PubMed
  233. Lenz KM, et al. 2018. J Neurosci. 38:8044. PubMed
  234. Nam H et al. 2019. Elife. 8 pii: e46683. PubMed
  235. Boucherie C, et al. 2018. Mol Psychiatry. 23:723. PubMed
  236. Leibinger M et al. 2019. Commun Biol. 0.304166667 . PubMed
  237. Mura M et al. 2019. Stem Cell Res. 1727:37:00 . PubMed
  238. Hansen M et al. 2017. Stem cell research. 25:34-37 . PubMed
  239. Yang SC, et al. 2019. FASEB J. 33:10577. PubMed
  240. Qiang L, et al. 2019. Hum Mol Genet. 28:1136. PubMed
  241. Kim K, et al. 2015. PLoS One. 10: 0142693. PubMed
  242. Mazzulli J, et al. 2016. Proc Natl Acad Sci U S A. 113: 1931 - 1936. PubMed
  243. Soares V, et al. 2016. Neuro Oncology. 10.1093/neuonc/now099. PubMed
  244. Mikami Y, et al. 2016. EBioMedicine. 11: 253-261. PubMed
  245. Pal-Ghosh S, et al. 2020. Invest Ophthalmol Vis Sci. 61:01:00. PubMed
  246. Janz A, et al. 2021. Stem Cell Research. 53:102256. PubMed
  247. Iwasa N, et al. 2021. Front Cell Neurosci. 15:605030. PubMed
  248. Boshans LL, et al. 2021. Sci Rep. 11:3552. PubMed
  249. Weiss FD, et al. 2021. Nat Commun. 12:2919. PubMed
  250. Mallach A, et al. 2021. Cells. 10:. PubMed
  251. Hernandez-Clavijo A, et al. 2022. Cell Physiol Biochem. 56:254. PubMed
  252. Wang W, et al. 2021. EMBO J. 40:e106771. PubMed
  253. Lin YC, et al. 2021. Nat Neurosci. 24:1077. PubMed
  254. Lim JY, et al. 2021. Stem Cell Res Ther. 12:402. PubMed
  255. Mifsud KR, et al. 2021. Nat Commun. 12:4737. PubMed
  256. Li Y, et al. 2022. Front Neurosci. 16:945277. PubMed
  257. Iyer AA, et al. 2022. Elife. 11:. PubMed
  258. Cheng Y, et al. 2022. Nat Commun. 13:4418. PubMed
  259. Ramirez S, et al. 2021. Cells. 10:. PubMed
  260. Wareham LK, et al. 2021. iScience. 24:103141. PubMed
  261. Abe K, et al. 2021. Biophys J. 120:3566. PubMed
  262. Mura M, et al. 2019. Stem Cell Research. 42:101658. PubMed
  263. Alkobtawi M, et al. 2021. Cell Reports. 35(12):109289. PubMed
  264. Li W, et al. 2021. Stem Cell Research. 53:102259. PubMed
  265. Haas M, et al. 2016. Cell Rep. 15:2251-2265. PubMed
  266. Itoh Y, et al. 2016. Proc Natl Acad Sci U S A. 113: 2955 - 2964. PubMed
  267. Nagao M, et al. 2016. Nat Commun. 7:11102. PubMed
  268. Taverna E, et al. 2016. Sci Rep. 6:21206. PubMed
  269. Ulbrich L, et al. 2016. Biochem J. 473: 423 - 434. PubMed
  270. Barry D, et al. 2012. J Neurosci. 32:6209-6219. PubMed
  271. Catanese A, et al. 2019. Autophagy. 15:1719. PubMed
  272. Pettingill P, et al. 2019. Brain. 142:3852. PubMed
  273. Wang SE, et al. 2019. Exp Neurobiol. 28:537. PubMed
  274. Song Z, et al. 2019. Front Cell Dev Biol. 0.352083333. PubMed
  275. Wang L et al. 2016. The Journal of comparative neurology. 524(11):2322-34 . PubMed
  276. Hansen M et al. 2017. Stem cell research. 25:42-45 . PubMed
  277. Herdy J et al. 2019. Elife. 8 pii: e41356. PubMed
  278. Vicario N et al. 2019. Molecular neurobiology. 56(11):7338-7354 . PubMed
  279. Child KM et al. 2018. The Journal of Neuroscience. 38(31):6806-6824 . PubMed
  280. Fujitani M, et al. 2017. Mol Psychiatry. 22:364. PubMed
  281. Hockman D, et al. 2018. Dev Biol. 444:s308. PubMed
  282. Barbiero I, et al. 2017. Hum Mol Genet. 26:3520. PubMed
  283. Coleman JH, et al. 2019. J Neurosci. 39:814. PubMed
  284. Luo C et al. 2019. eLife. 8 pii: e40197. PubMed
  285. Liu L et al. 2017. Cell metabolism. 26(5):719-737 . PubMed
  286. Knudsen JG et al. 2018. Cell metabolism. 29(2):430-442 . PubMed
  287. Millan‐Zambrano G et al. 2018. Molecular cell. 72(4):625-635 . PubMed
  288. Sevilla A et al. 2018. Stem cell research. 29:99-102 . PubMed
  289. Muthusamy N, et al. 2018. Sci Rep. 8:1766. PubMed
  290. Kuwahara H, et al. 2018. Sci Rep. 8:4377. PubMed
  291. Anne Jacob et al. 2018. Journal of neurochemistry. 146(3):251-268 . PubMed
  292. Lehrman EK et al. 2018. Neuron. 100(1):120-134 . PubMed
  293. Valdez C, et al. 2017. Hum Mol Genet. 26:4861. PubMed
  294. Moakley D, et al. 2019. Sci Rep. 9:10835. PubMed
  295. Malkemper EP, et al. 2018. Biol Open. 7:bio034462. PubMed
  296. Stratton JA et al. 2018. Cell reports. 24(10):2561-2572 . PubMed
  297. Neurohr GE, et al. 2019. Cell. 176:1083. PubMed
  298. Hermanto Y et al. 2019. Journal of neuroscience research. 97(7):828-845 . PubMed
  299. An D, et al. 2019. Elife. 8:e44423. PubMed
  300. Voronova A et al. 2017. Neuron. 94(3):500-516 . PubMed
  301. Hilla AM et al. 2017. The Journal of Neuroscience. 37(25):6113-6124 . PubMed
  302. Bustos F, et al. 2018. Cell Rep. 2.06875. PubMed
  303. Mayanagi T, et al. 2020. Front Cell Neurosci. 0.933333333. PubMed
  304. Arsić A, et al. 2020. Sci Rep. 10:6441. PubMed
  305. Edwards G, et al. 2020. Cell Death Dis. 11:254. PubMed
  306. Nishimura K, et al. 2017. PLoS One. 12:e0170568. PubMed
  307. Roselló-Busquets C, et al. 2020. Front Mol Neurosci. 13:56. PubMed
  308. Wang X, et al. 2019. Front Neurosci. 1.324305556. PubMed
  309. Caiazzo M, et al. 2016. Nat Mater. 0.1038/nmat4536. PubMed
  310. Fan C, et al. 2016. Sci Rep. 6:19579. PubMed
  311. Vanderperre B, et al. 2016. PLoS Genet. 12: 1006056. PubMed
  312. Wang T, et al. 2016. Nat Commun. 7: 12976. PubMed
  313. Pei S, et al. 2016. Sci Rep. 6:33822. PubMed
  314. M Rodriguez, S Noctor, E Muñoz 2016. PLoS One. 11:e0167063. PubMed
  315. Ahn LY, et al. 2021. J Neurosci Res. 99:110. PubMed
  316. Black JB, et al. 2020. Cell Rep. 33:108460. PubMed
  317. Birkhoff JC, et al. 2020. Hum Mol Genet. 29:2535. PubMed
  318. Pereiro X, et al. 2020. Cells. 9:00. PubMed
  319. Berenguer-Escuder C, et al. 2020. Human Molecular Genetics. 29(8):1353-1364. PubMed
  320. Tapias A, et al. 2021. eLife. 10:00. PubMed
  321. Dong L, et al. 2021. Stem Cell Research. 53:102260. PubMed
  322. Zhang T, et al. 2021. STAR Protocols. 2(1):100346. PubMed
  323. Arribas-Carreira L, et al. 2019. Stem Cell Research. 39:101503. PubMed
  324. Schoger E, et al. 2021. Stem Cell Research. 56:102518. PubMed
  325. Klima S, et al. 2020. ALTEX. . PubMed
  326. Guerriero I, et al. 2021. PLoS One. 16:e0253828. PubMed
  327. Diao X, et al. 2021. Cells. 10:. PubMed
  328. Lamotte JD, et al. 2021. Front Pharmacol. 11:617867. PubMed
  329. Paik S, et al. 2021. Biomedicines. 9:. PubMed
  330. Nehme R, et al. 2022. Nat Commun. 13:3690. PubMed
  331. Xia L, et al. 2022. Front Pharmacol. 13:881195. PubMed
  332. Zhang L, et al. 2022. Front Aging Neurosci. 14:926485. PubMed
  333. Lu P, et al. 2022. Invest Ophthalmol Vis Sci. 63:18. PubMed
  334. Heuermann ML, et al. 2022. Front Cell Neurosci. 16:841864. PubMed
  335. McSweeney D, et al. 2022. iScience. 25:105187. PubMed
  336. Ha GH, et al. 2022. Aging (Albany NY). 14:. PubMed
  337. Meyer Zu Reckendorf S, et al. 2022. J Neurosci. 42:2474. PubMed
  338. van Niekerk EA, et al. 2022. Cell Rep Methods. 2:100255. PubMed
  339. Nouri P, et al. 2022. Cells. 11:. PubMed
  340. Amo-Aparicio J, et al. 2021. Theranostics. 11:9805. PubMed
  341. Fagerlund I, et al. 2021. Cells. 11:. PubMed
  342. Petrovic A, et al. 2022. Int J Mol Sci. 23:. PubMed
  343. Colombo S, et al. 2022. Development. 149:. PubMed
  344. Sidoli M, et al. 2021. J Neurosci. 41:4536. PubMed
  345. Simone R, et al. 2021. Nature. 594:117. PubMed
  346. Li A, et al. 2021. STAR Protoc. 2:100580. PubMed
  347. Osuka S, et al. 2021. J Clin Invest. 131: . PubMed
  348. Lasman L, et al. 2020. Genes Dev. 34:1373. PubMed
  349. Wong HS, et al. 2021. Cell. . PubMed
  350. Kim JW, et al. 2020. Cell Stem Cell. 27(4):633-645.e7. PubMed
  351. Evsen L, et al. 2020. Development. 147:00:00. PubMed
  352. Huang YA, et al. 2020. J Cell Sci. 133:00:00. PubMed
  353. Levin G, et al. 2020. Front Bioeng Biotechnol. 0.663888889. PubMed
  354. Seo HH, et al. 2020. Emerg Microbes Infect. 1.724305556. PubMed
  355. Laura Kerosuo, Marianne E. Bronner 2016. Cell Rep. 17:2648-2659. PubMed
  356. George L, et al. 2016. Dev Biol. 413:70-85. PubMed
  357. Ferletta M, et al. 2011. Int J Cancer. 129:45-60. PubMed
  358. Banal C, et al. 2020. Stem Cell Research. 72.78888889. PubMed
  359. Zhao J, et al. 2020. Aging (Albany NY). 12:5590. PubMed
  360. Themeli M, et al. 2020. Stem Cell Reports. 14:300. PubMed
  361. Ding D, et al. 2020. J Otol. 15:36. PubMed
  362. Ilouz R et al. 2017. eLife. 6 pii: e17681. PubMed
  363. Kwart D et al. 2019. Neuron. 104(2):256-270 . PubMed
  364. Di Bella DJ, et al. 2019. Cell Rep. 28:2264. PubMed
  365. Velychko S et al. 2019. Cell reports. 27(1):30-39 . PubMed
  366. Kim J, et al. 2018. Development. 145. PubMed
  367. Yang T et al. 2018. Cell reports. 24(10):2694-2708 . PubMed
  368. Cheng LS, et al. 2017. Pediatr Res. 81:838. PubMed
  369. Augé E, et al. 2018. Sci Rep. 8:13525. PubMed
  370. Shin BC et al. 2018. The Journal of Neuroscience. 38(44):9579-9599 . PubMed
  371. Cárdenas A et al. 2018. Cell. 174(3):590-606 . PubMed
  372. Goffena J, et al. 2018. Nat Commun. 9:889. PubMed
  373. Ogawa Y, et al. 2017. PLoS One. 12(6):e0178978. PubMed
  374. Chau KF, et al. 2018. Elife. 19:E663. PubMed
  375. Sun S et al. 2018. Cell. 174(5):1247-1263 . PubMed
  376. Yi‐Lan Weng et al. 2018. Neuron. 97(2):313-325 . PubMed
  377. Bachmann SO, et al. 2019. Transl Psychiatry. 9:29. PubMed
  378. Sabo JK, et al. 2017. Ann Neurol. 81:560. PubMed
  379. Gao L, et al. 2019. Front Cell Neurosci. 13:316. PubMed
  380. Shao Q et al. 2019. PLoS One. 14(6):e0218811 . PubMed
  381. Mohlin S, et al. 2019. EMBO Mol Med. 11:e10058. PubMed
  382. Ibañez Rodriguez MP et al. 2018. The Journal of comparative neurology. 526(15):2462-2481 . PubMed
  383. Duan RS, et al. 2018. Cell Death Differ. 25:1598. PubMed
  384. Pollen AA, et al. 2019. Cell. 176:743. PubMed
  385. Corman A, et al. 2019. Cell Chem Biol. 26:235. PubMed
  386. Molotkov A et al. 2017. Developmental cell. 41(5):511-526 . PubMed
  387. Yang C, et al. 2020. Neuron. 105:276. PubMed
  388. Marchetta P, et al. 2020. Front Aging Neurosci. 12:83. PubMed
  389. Wirt S, et al. 2010. J Cell Biol. 191:809-825. PubMed
  390. Wang Q, et al. 2016. Sci Rep. 6:19003. PubMed
  391. Petracca Y, et al. 2016. Development. 143: 880 - 891. PubMed
  392. Lalli M, et al. 2016. Hum Mol Genet. 25: 1294-1306. PubMed
  393. Thakurela S, et al. 2016. Sci Rep. 6: 25828. PubMed
  394. Bedogni F, et al. 2016. Cereb Cortex. 26: 2517 - 2529. PubMed
  395. Landegger L, et al. 2017. Nat Biotechnol. 35:280-284. PubMed
  396. Pournasr B, et al. 2020. Stem Cell Res. 48:101953. PubMed
  397. Trapecar M, et al. 2021. Sci Adv. 7:00. PubMed
  398. Smith KE, et al. 2020. Journal of Neuroscience Research. 99(2):679-698. PubMed
  399. Isaja L, et al. 2021. Stem Cell Research. 53:102325. PubMed
  400. Elsayed AK, et al. 2021. Stem Cell Research. 56:102500. PubMed
  401. Bargagna-Mohan P, et al. 2020. J Neurosci Res. . PubMed
  402. Lee N, et al. 2021. Biochem Biophys Rep. 100973:26. PubMed
  403. Zheng Z, et al. 2021. Cell Biol Toxicol. Online ahead of prin. PubMed
  404. Lim SH, et al. 2020. J Cell Sci. . PubMed
  405. Salti A, et al. 2021. Cells. 10:. PubMed
  406. Araki R, et al. 2021. Heliyon. 7:e08071. PubMed
  407. Ye E, et al. 2022. Int J Oncol. 60:. PubMed
  408. Taïb S, et al. 2022. Elife. 11:. PubMed
  409. Bérenger-Currias NM, et al. 2022. J Tissue Eng. 13:20417314221103042. PubMed
  410. Fujiwara N, et al. 2022. Pediatr Surg Int. 39:18. PubMed
  411. Zhu Z, et al. 2022. Aging Cell. 21:e13587. PubMed
  412. Schaeffer J, et al. 2022. Front Cell Dev Biol. 10:917589. PubMed
  413. Li J, et al. 2021. Neural Plast. 2021:4894881. PubMed
  414. Wilmerding A, et al. 2021. Int J Mol Sci. 22:. PubMed
  415. Hu D, et al. 2021. Nat Commun. 12:5305. PubMed
  416. Russo-Savage L, et al. 2020. Neurobiol Aging. 95:69. PubMed
  417. Urciuolo A, et al. 2020. Nat Biomed Eng. 4:901. PubMed
  418. Sadick JS, et al. 2020. Ann Biomed Eng. 48:2218. PubMed
  419. Lecomte A, et al. 2020. Adv Biosyst. e2000114:4. PubMed
  420. Wang L, et al. 2020. Nat Commun. 3.2625. PubMed
  421. Sheehan CJ, et al. 2020. Development. 147:00:00. PubMed
  422. Zabolocki M, et al. 2020. Nat Commun. 4.3125. PubMed
  423. Liu R, et al. 2021. Oncol Lett. 21:06. PubMed
  424. Zhang X, et al. 2020. Sci Adv. 6:00. PubMed
  425. Sadick J, et al. 2016. Sci Rep. 6: 33999. PubMed
  426. Guo S, Du Y, Liu X 2016. Nat Commun. 7:12230. PubMed
  427. Kushwaha R, et al. 2016. Stem Cell Reports. 6:772-783. PubMed
  428. Paquet D, et al. 2016. Nature. 533: 125-129. PubMed
  429. Binder Z, et al. 2016. PLoS One. 11: 0150271. PubMed
  430. He H, et al. 2016. J Neurosci. 36: 3079 - 3091. PubMed
  431. Khong ZJ, et al. 2020. Cell Death Dis. 11:182. PubMed
  432. Pinheiro H, et al. 2018. Front Pharmacol. 0.527083333. PubMed
  433. Ichihara–Tanaka K, et al. 2017. J Histochem Cytochem. 65:513. PubMed
  434. Harrington AJ et al. 2016. eLife. 5 pii: e20059. PubMed
  435. Michael Lerche et al. 2017. Structure (London, England : 1993). 25(8):1175-1186 . PubMed
  436. Larhammar M et al. 2017. eLife. 6 pii: e20725. PubMed
  437. Lavado A et al. 2018. Dev Cell. 47(5):576-591 . PubMed
  438. Freeman S et al. 2019. EMBO Rep. 20(9):e47097 . PubMed
  439. Kaur T, et al. 2019. Front Neurosci. 13:620. PubMed
  440. Nash B et al. 2019. eNeuro. 6(4) pii: ENEURO. PubMed
  441. Sarkar C, et al. 2019. Autophagy. N/A. PubMed
  442. Tramarin M, et al. 2018. Hum Mol Genet. 27:2052. PubMed
  443. Xue J, et al. 2017. ACS Appl Mater Interfaces. 9:12299. PubMed
  444. Toda T, et al. 2017. Cell Stem Cell. 21:618. PubMed
  445. Amaral JD, et al. 2019. Front Chem. 7:15. PubMed
  446. Wang XW, et al. 2018. Cell Rep. 24:2540. PubMed
  447. Tavano S et al. 2018. Neuron. 97(6):1299-1314 . PubMed
  448. Luisier R, et al. 2018. Nat Commun. 8:6458. PubMed
  449. Lehtonen Ŝ et al. 2018. Stem cell research. 30:96-99 . PubMed
  450. Qiang L et al. 2018. Current biology : CB. 28(13):2181-2189 . PubMed
  451. Hor JH, et al. 2018. Cell Death Dis. 9:1100. PubMed
  452. Gupta S et al. 2017. Journal of neurochemistry. 145(3):188-203 . PubMed
  453. Howlett EH, et al. 2017. Hum Mol Genet. 26:4340. PubMed
  454. Zunke F et al. 2017. Neuron. 97(1):92-107 . PubMed
  455. Fernandes KA, et al. 2018. Exp Eye Res. 171:54. PubMed
  456. Linkous A et al. 2019. Cell reports. 26(12):3203-3211 . PubMed
  457. Pronin A, et al. 2019. Front Mol Neurosci. 12:36. PubMed
  458. Meijer M et al. 2019. Cell Rep. 27(7):2199-2211 . PubMed
  459. Lin CI et al. 2019. eNeuro. 6(4) pii: ENEURO. PubMed
  460. Auboyer L et al. 2019. Stem Cell Res. 1723:41:00 . PubMed
  461. Kurtenbach S et al. 2017. PloS one. 12(11):e0187576 . PubMed
  462. Yu M et al. 2017. Cell research. 27(12):1441-1465 . PubMed
  463. Huh CJ et al. 2016. eLife. 5 pii: e18648. PubMed
  464. Li J, et al. 2018. Neural Plast. 2018:6890613. PubMed
  465. Chen YT, et al. 2019. Stem Cell Res Ther. 0.6875. PubMed
  466. Syal C, et al. 2020. Theranostics. 10:6337. PubMed
  467. Pinto M, et al. 2016. J Cell Biol. 212: 789 - 801. PubMed
  468. Okamoto M, et al. 2016. Nat Commun. 7: 11349. PubMed
  469. Liu X, et al. 2016. Nat Commun. 7:11508. PubMed
  470. Grandi FC, et al. 2020. Front Mol Neurosci. 0.599305556. PubMed
  471. Ewan EE, et al. 2021. Sci Rep. 0.718055556. PubMed
  472. Brievac D, et al. 2020. Journal of Neurochemistry. 157(3):666-683. PubMed
  473. Hu Z, et al. 2020. Cell Rep. 107657:31. PubMed
  474. de Matos AM, et al. 2020. J Med Chem. 63:11663. PubMed
  475. Calamini B, et al. 2021. Dis Model Mech. 14:. PubMed
  476. Gandhi S, et al. 2021. Development. 148:. PubMed
  477. Stern S, et al. 2021. Neuron. 109:3436. PubMed
  478. Nath M, et al. 2022. Eneuro. 9:. PubMed
  479. Contreras E, et al. 2022. Cell Tissue Res. :. PubMed
  480. Sluysmans S, et al. 2021. Mol Biol Cell. 32:ar34. PubMed
  481. Ma C, et al. 2022. Int J Mol Med. 50:. PubMed
  482. Khan M, et al. 2021. Cell. 184:5932. PubMed
  483. Xu PF, et al. 2021. Nature Communications. 12(1):3277. PubMed
  484. Anderson EM, et al. 2021. Addiction Biology. :e13060. PubMed
  485. Lin NH, et al. 2021. The FASEB Journal. 35(5):e21614. PubMed
  486. Leibinger M, et al. 2021. Nature Communications. 12(1):391. PubMed
  487. Huang S, et al. 2020. Cell Rep. 33:108394. PubMed
  488. Rubio A, et al. 2016. Sci Rep. 6:37540. PubMed
  489. Intoh A, et al. 2016. Hum Mol Genet. 10.1093/hmg/ddw053. PubMed
  490. Sancho-Martinez I, et al. 2016. Nat Commun. 7:10743. PubMed
  491. Jouhilahti E, et al. 2008. J Histochem Cytochem. 56:1113-1119. PubMed
  492. Gilliam EA, et al. 2020. American Journal of Physiology-Gastrointestinal and Liver Physiology. 319(2):G261-G279.. PubMed
  493. Dionisi C, et al. 2020. Sci Rep. 10:7752. PubMed
  494. Lindsay CD, et al. 2019. Acta Biomater. 95:225. PubMed
  495. Makdissy N, et al. 2018. Stem Cell Res Ther. 0.466666667. PubMed
  496. Mettang M, et al. 2018. FASEB J. 32:1916. PubMed
  497. Chen X et al. 2017. Developmental cell. 43(5):563-576 . PubMed
  498. Hegarty DM, et al. 2017. J Comp Neurol. 525:2019. PubMed
  499. Tsuboi M, et al. 2018. Dev Cell. 47:758. PubMed
  500. Sharma N et al. 2019. Neuron. 102(2):390-406 . PubMed
  501. Mo J, et al. 2017. Invest Ophthalmol Vis Sci. 58:137. PubMed
  502. Rhee HJ et al. 2019. Cell Rep. 27(7):2212-2228 . PubMed
  503. Makar T, et al. 2018. Stem Cell Res Ther. 9:127. PubMed
  504. Debadrita Bhattacharya et al. 2018. eLife. 7 pii: e40556. PubMed
  505. Zahr SK et al. 2018. Neuron. 97(3):520-537 . PubMed
  506. Kim YJ, et al. 2018. Neuron. 100:1180. PubMed
  507. Flaherty E,et al. 2017. NPJ Schizophr.. 10.1038/s41537-017-0033-5. PubMed
  508. Ryan T, et al. 2018. Nat Commun. 9:817. PubMed
  509. Moon KH et al. 2018. Developmental cell. 44(1):13-28 . PubMed
  510. Xu Z, et al. 2019. Front Neurosci. 12:970. PubMed
  511. Joanna Ruth Appel et al. 2018. The Journal of Neuroscience. 38(26):5949-5968 . PubMed
  512. Vyas P, et al. 2019. Sci Rep. 9:5549. PubMed
  513. Zhang N, et al. 2019. Adv Sci (Weinh). 6:1800808. PubMed
  514. Singh K, et al. 2018. Front Mol Neurosci. 11:30. PubMed
  515. Friocourt F et al. 2019. The Journal of comparative neurology. 527(12):2009-2029 . PubMed
  516. Weng YL, et al. 2017. Neuron. 94:337. PubMed
  517. Espuny‐Camacho I et al. 2017. Neuron. 93(5):1066-1081 . PubMed
  518. Park JH, et al. 2018. Mol Cell Biol. 38:e00217. PubMed
  519. Ozaki K, et al. 2019. Invest Ophthalmol Vis Sci. 60:4151. PubMed
  520. Llères D, et al. 2019. Genome Biol. 1.022222222. PubMed
  521. Dourado NS, et al. 2020. Front Aging Neurosci. 12:119. PubMed
  522. Götzl JK, et al. 2018. Mol Neurodegener. 13:48. PubMed
  523. Xue Y, et al. 2016. Nat Neurosci. 19: 807-15. PubMed
  524. Muscat A, et al. 2016. Clin Cancer Res. 22: 3560 - 3570. PubMed
  525. Sandor C, et al. 2017. Hum Mol Genet. 10.1093/hmg/ddw412. PubMed
  526. Ingersoll MA, et al. 2020. Sci Adv. 6:00. PubMed
  527. Jiang B, et al. 2020. Sci Adv. 6:00. PubMed
  528. Barbuti PA, et al. 2020. Cells. 9:00. PubMed
  529. Vila-Cejudo M, et al. 2018. Journal of Assisted Reproduction and Genetics. 36(1):99-111. PubMed
  530. Koinuma S, et al. 2020. Journal of Neurochemistry. 157(4):1196-1206. PubMed
  531. Dementyeva EV, et al. 2021. Stem Cell Research. 53:102344. PubMed
  532. Han JS, et al. 2020. Proc Natl Acad Sci U S A. 23073:117. PubMed
  533. Gupta S, et al. 2021. STAR Protoc. 100319:2. PubMed
  534. Hertzano R, et al. 2020. Laryngoscope. . PubMed
  535. Borys BS, et al. 2021. Stem Cell Res Ther. 12:55. PubMed
  536. Little JN, et al. 2021. J Neurosci. 41:3344. PubMed
  537. Sanchez CG, et al. 2021. Commun Biol. 4:736. PubMed
  538. Wang L, et al. 2021. Nat Med. 27:1600. PubMed
  539. Sepehrimanesh M, et al. 2021. STAR Protoc. 2:100917. PubMed
  540. Barbuti PA, et al. 2021. Sci Rep. 11:21946. PubMed
  541. Meng X, et al. 2022. Proc Natl Acad Sci U S A. 119:. PubMed
  542. Argolo DS, et al. 2022. Int J Tryptophan Res. 15:11786469211069946. PubMed
  543. Li Y, et al. 2022. J Cell Biol. 221:. PubMed
  544. Yamamoto Y, et al. 2022. Life Sci Alliance. 5:. PubMed
  545. Chen J, et al. 2021. Int J Mol Sci. 23:. PubMed
  546. Zhang H, et al. 2022. Elife. 11:. PubMed
  547. Tang J, et al. 2022. Antioxidants (Basel). 11:. PubMed
  548. Reyes RV, et al. 2022. Front Neurosci. 16:908719. PubMed
  549. He B, et al. 2021. J Anat. 239:913. PubMed
  550. Arsic A, et al. 2022. Nat Commun. 13:314. PubMed
  551. Calamini B, et al. 2021. Dis Model Mech. . PubMed
  552. Brown D, et al. 2021. Neurotherapeutics. 18:387. PubMed
  553. Wang M, et al. 2021. Neuron. 109:257. PubMed
  554. Ren J, et al. 2021. Cells. 10:. PubMed
  555. Cui K, et al. 2020. Microsyst Nanoeng. 6:49. PubMed
  556. Cuddy LK, et al. 2021. STAR Protoc. 100340:2. PubMed
  557. Matern MS, et al. 2020. Development. :147. PubMed
  558. Nikulina E, et al. 2020. FEBS Lett. 1389:594. PubMed
  559. Ghita L, et al. 2021. Journal of Neuroscience Research. :. PubMed
  560. Simon DJ, et al. 2021. Developmental Cell. 56(7):976-984.e3. PubMed
  561. Maor-Nof M, et al. 2021. Cell. 184(3):689-708.e20. PubMed
  562. Kraemer BR, et al. 2020. Neuroscience. 453:222-236. PubMed
  563. Schörnig M, et al. 2021. Elife. 10:00. PubMed
  564. Camilieri-Asch V, et al. 2020. Front Neuroanat. 14:560534. PubMed
  565. Durak O, et al. 2016. Nat Neurosci. 19:1477-1488. PubMed
  566. Drobish J, et al. 2016. Toxicol Sci. 154(2):309-319. PubMed
  567. Marchetto M, et al. 2016. Mol Psychiatry. 10.1038/mp.2016.95. PubMed
  568. Wang W, et al. 2016. Nat Commun. 7:10936. PubMed
  569. Tanimoto R, et al. 2016. Sci Rep. 6:22071. PubMed
  570. Stathakos P, et al. 2020. Autophagy. :1. PubMed
  571. Huang YA, et al. 2019. J Neurosci. 39:7408. PubMed
  572. Dang LT, et al. 2020. Front Cell Neurosci. 14:122. PubMed
  573. Sloan SA et al. 2017. Neuron. 95(4):779-790 . PubMed
  574. Shao Q et al. 2017. The Journal of Neuroscience. 37(23):5620-5633 . PubMed
  575. Wu JS et al. 2017. The Journal of comparative neurology. 526(3):425-438 . PubMed
  576. Wu C, et al. 2019. Cell Rep. 26:1143. PubMed
  577. Vassilev V, et al. 2017. Dev Cell. 43:463. PubMed
  578. Kim J, et al. 2017. Histochem Cell Biol. 148:489. PubMed
  579. Thayer JA, et al. 2019. Autophagy. 7:1-14. PubMed
  580. Liu WA, et al. 2018. Genes Dev. 32:763. PubMed
  581. Trajkovic K, et al. 2019. PLoS One. 14:e0211727. PubMed
  582. Oksanen M et al. 2018. Stem cell research. 31:181-185 . PubMed
  583. Johansson E, et al. 2017. Cell Rep. 10.1016/j.celrep.2017.07.049. PubMed
  584. Wu X, et al. 2018. Cell. 172:423. PubMed
  585. Buijsen RAM et al. 2018. Stem cell research. 29:125-128 . PubMed
  586. Miquel‐Serra L et al. 2018. Stem cell research. 24:155-159 . PubMed
  587. Senft AD, et al. 2018. Cell Rep. 24:1977. PubMed
  588. Gao L, et al. 2019. Sci Rep. 9:3462. PubMed
  589. Xu Z, et al. 2018. Development. 145:. PubMed
  590. Christiansen EM, et al. 2018. Cell. 173:792. PubMed
  591. Rich CA, et al. 2018. Glia. 66:2617. PubMed
  592. Heil C, et al. 2019. Open Biol. 9:180145. PubMed
  593. Wanner R, et al. 2019. Front Neurol. 10:310. PubMed
  594. Hickey SL et al. 2019. Cell reports. 27(6):1699-1711 . PubMed
  595. Suarato G, et al. 2017. Biomaterials. 112:176. PubMed
  596. Watanabe Y, et al. 2018. Development. 145. PubMed
  597. Chanda S et al. 2019. Cell Stem Cell. 25(1):103-119 . PubMed
  598. Wu Z, et al. 2019. Neuron. 101:635. PubMed
  599. Bachmann SB, et al. 2019. Cell Rep. 27:3305. PubMed
  600. Kaplan A, et al. 2017. Neuron. 93:1082. PubMed
  601. Tozer S, et al. 2017. Neuron. 93:542. PubMed
  602. Leibinger M et al. 2017. Proceedings of the National Academy of Sciences of the United States of America. 114(27):E5454-E5463 . PubMed
  603. Syc–Mazurek SB, et al. 2018. Cell Death Dis. 1.135416667. PubMed
  604. Kang PH, et al. 2020. Mol Biol Cell. 31:386. PubMed
  605. Tehrani S, et al. 2018. Sci Rep. 8:4453. PubMed
  606. Russo R, et al. 2018. Cell Death Dis. 1.05625. PubMed
  607. Suenkel C, et al. 2020. Cell Reports. 30(7):2170-2179. PubMed
  608. Peitz M, et al. 2020. STAR Protoc. 1:100038. PubMed
  609. Quintes S, et al. 2016. Nat Neurosci. 10.1038/nn.4321. PubMed
  610. Demais V, et al. 2016. J Neurosci. 36: 8012 - 8025. PubMed
  611. Borromeo M, et al. 2016. Cell Rep. 16:1259-1272. PubMed
  612. Borgs L, et al. 2016. Sci Rep. 6: 33377. PubMed
  613. Enriquez‐Rios V et al. 2017. The Journal of Neuroscience. 37(4):893-905 . PubMed
  614. Shi W, et al. 2017. Nat Neurosci. 10.1038/nn.4519. PubMed
  615. Brann DH, et al. 2020. Sci Adv. 6:00. PubMed
  616. McNeely KC, et al. 2020. Proc Natl Acad Sci U S A. 117:9584. PubMed
  617. Li Y, et al. 2021. Stem Cell Research. 55:102460. PubMed
  618. Hilla AM, et al. 2018. BIO-PROTOCOL. 8(16):e2979. PubMed
  619. Kitajima R, et al. 2020. Stem Cell Res. 101749:44. PubMed
  620. Fouda AY, et al. 2020. Invest Ophthalmol Vis Sci. 51:61. PubMed
  621. Petrovic A, et al. 2021. Front Cell Neurosci. 15:661492. PubMed
  622. Liang D, et al. 2021. Nat Neurosci. 24:941. PubMed
  623. Lautz JD, et al. 2021. Cell Rep. 37:110076. PubMed
  624. De La Rossa A, et al. 2022. Elife. 11:. PubMed
  625. Rabadán MA, et al. 2022. Nat Commun. 13:3340. PubMed
  626. Williams LA, et al. 2022. Mol Ther Nucleic Acids. 29:189. PubMed
  627. Vahsen BF, et al. 2022. Sci Rep. 12:12606. PubMed
  628. Sefiani A, et al. 2022. Sci Rep. 12:13125. PubMed
  629. Tay SH, et al. 2021. Methods Mol Biol. 2549:359. PubMed
  630. Fisher ES, et al. 2022. J Neuroinflammation. 19:266. PubMed
  631. Rantanen LM, et al. 2022. Cells. 11:. PubMed
  632. Hamity MV, et al. 2022. Invest Ophthalmol Vis Sci. 63:38. PubMed
  633. Lam AN, et al. 2021. Data Brief. 35:106897. PubMed
  634. Cui K, et al. 2022. Cell Regen. 11:7. PubMed
  635. Zhao D, et al. 2021. Cell Death Differ. 28:337. PubMed
  636. Schenk MS, et al. 2021. Transl Vis Sci Technol. 10:22. PubMed
  637. Dong Y, et al. 2021. STAR Protoc. 2:100853. PubMed
  638. Calado SM, et al. 2021. Stem Cell Research. 55:102462. PubMed
  639. Bieler M, et al. 2021. Journal of Comparative Neurology. 529(12):3194-3205. PubMed
  640. Kondo N, et al. 2020. Cancers (Basel). 12:00. PubMed
  641. Friocourt F, et al. 2017. Sci Rep. 7:37569. PubMed
  642. Fimiani C, et al. 2016. Sci Rep. 6:39311. PubMed
  643. Damiani D, et al. 2016. Nat Commun. 7:13509. PubMed
  644. Hegazy A, et al. 2016. J Biol Chem. 291: 21496 - 21509. PubMed
  645. Maison S, Liberman L, Liverman M 2016. eNeuro. 3: ENEURO.0207-16.2016. PubMed
  646. Edmondson R, Adock A, Yang L 2016. PLoS One. 11: 0158116. PubMed
  647. Jablonski K, et al. 2016. Stem Cell Reports. 8: 1119-1127. PubMed
  648. Rraklli V, et al. 2016. Stem Cell Res. 16:1-9. PubMed
  649. Kizuka Y, et al. 2016. Biochem J. 473: 21 - 30. PubMed
  650. Kim K, et al. 2013. J Cell Biol. 200:443-458. PubMed
  651. Cesca F, et al. 2012. Cell Death Differ. 19:194-208. PubMed
  652. Yao H, et al. 2020. Sci Rep. 10:17445. PubMed
  653. Matthies D, et al. 2020. Sci Rep. 10:11953. PubMed
  654. Hattori Y, et al. 2020. Nat Commun. 11:1631. PubMed
  655. Duncan DS, et al. 2018. Front Neurosci. 0.9875. PubMed
  656. Welsbie DS et al. 2017. Neuron. 94(6):1142-1154 . PubMed
  657. Belle M et al. 2017. Cell. 169(1):161-173 . PubMed
  658. Walker LJ et al. 2017. eLife. 6 pii: e22540. PubMed
  659. Mura M et al. 2019. Stem Cell Res. 1727:31:00 . PubMed
  660. Gao F et al. 2019. Mol Cell. 75(5):891-904 . PubMed
  661. Kurabayashi N, et al. 2018. Development. 145. PubMed
  662. Miesfeld JB et al. 2017. Gene expression patterns : GEP. 27:114-121 . PubMed
  663. Calatayud C, et al. 2019. Sci Rep. 9:6811. PubMed
  664. Pai EL et al. 2019. Cell reports. 26(5):1157-1173 . PubMed
  665. Teng X, et al. 2018. Thyroid. 28:667. PubMed
  666. Sun L, et al. 2017. Oncotarget. 8:40065. PubMed
  667. Spitalieri P, et al. 2018. Front Physiol. 9:967. PubMed
  668. Erin Frey et al. 2018. eNeuro. 5(3) pii: ENEURO. PubMed
  669. Mura M et al. 2018. Stem cell research. 29:157-161 . PubMed
  670. Liu P, et al. 2017. Stem Cell Rep. 10.1016/j.stemcr.2017.05.007. PubMed
  671. Sommer A et al. 2018. Cell stem cell. 23(1):123-131 . PubMed
  672. Mains RE et al. 2018. Endocrinology. 159(7):2621-2639 . PubMed
  673. Kelly SM et al. 2018. Neuron. 99(2):345-361 . PubMed
  674. Han S, et al. 2018. Development. 145:. PubMed
  675. Friedl RM, et al. 2019. Dis Model Mech. 0.5. PubMed
  676. Khayati K, et al. 2017. FASEB J. 31:598. PubMed
  677. Comai G et al. 2019. Elife. 8 pii: e47460. PubMed
  678. Lee SG et al. 2018. Stem Cell Res. 31:197-200 . PubMed
  679. Zhu J et al. 2017. Cell stem cell. 20(3):374-384 . PubMed
  680. Gouti M, et al. 2017. Dev Cell. 41:243. PubMed
  681. Levin E et al. 2017. Scientific reports. 7(1):643 . PubMed
  682. Tokuyama MA, et al. 2018. Dev Biol. 433:287. PubMed
  683. Xie Y, et al. 2019. RNA Biol. 0.723611111. PubMed
  684. Yang D, et al. 2019. Elife. 8:e49249. PubMed
  685. Heinrich A, et al. 2020. Cell Rep. 31:107513. PubMed
  686. Park S, et al. 2020. PLoS Biol. 18:e3000296. PubMed
  687. Pappa S, et al. 2019. Proc Natl Acad Sci U S A. 116:19464. PubMed
  688. Marquardt LM, et al. 2020. Sci Adv. 6:eaaz1039. PubMed
  689. Flores-Otero J, et al. 2007. J Neurosci. 27:14023-14034. PubMed
  690. Wang L, Hou S, Han Y 2016. Nat Neurosci. 19: 888-896. PubMed
  691. Roese-Koerner B, et al. 2016. Stem Cell Reports. 7:207-219. PubMed
  692. Choi R, et al. 2020. Laryngoscope Investig Otolaryngol. 0.885416667. PubMed
  693. Ng AQE, et al. 2020. Cell Reports. 30(5):1434-1446.e7. PubMed
  694. Hawkins FJ, et al. 2020. Cell Stem Cell. 28(1):79-95.e8. PubMed
  695. Arber C, et al. 2021. Cell Reports. 34(2):108615. PubMed
  696. Zhang X, et al. 2021. Cell Reports. 34(11):108830. PubMed
  697. Czeisler C, et al. 2016. Journal of Comparative Neurology. 524(17):3485-3502. PubMed
  698. Abreu CA, et al. 2021. Journal of Neurochemistry. 158(3):694-709. PubMed
  699. Doucet-O'Hare TT, et al. 2021. Sci Rep. 11:12893. PubMed
  700. Gandhi S, et al. 2021. Development. 148:dev193565. PubMed
  701. Ketschek A, et al. 2021. J Neurosci. 41:6637. PubMed
  702. Park SH, et al. 2021. Biochem Pharmacol. 188:114520. PubMed
  703. Oksdath Mansilla M, et al. 2021. BMC Biomed Eng. 3:6. PubMed
  704. Xu X, et al. 2022. Biology (Basel). 11:. PubMed
  705. Namchaiw P, et al. 2022. PLoS One. 17:e0273458. PubMed
  706. Wu C, et al. 2022. J Hum Genet. :. PubMed
  707. Wilmerding A, et al. 2022. Neoplasia. 24:120. PubMed
  708. Yang Y, et al. 2022. Nucleic Acids Res. 50:191. PubMed
  709. Hilton BJ, et al. 2021. Neuron. S0896-6273:00775-3. PubMed
  710. Bassil R, et al. 2021. Nat Commun. 12:5220. PubMed
  711. Vaes N, et al. 2021. EMBO Rep. 22:e51913. PubMed
  712. Bouma MJ, et al. 2019. Stem Cell Research. 41:101654. PubMed
  713. Rebs S, et al. 2021. Stem Cell Research. 53:102263. PubMed
  714. Gao T, et al. 2021. JCI Insight. 6(10):. PubMed
  715. Liu W, et al. 2020. J Exp Med. 217:00:00. PubMed
  716. Franco A, et al. 2020. Elife. 9:00. PubMed
  717. Chen W, et al. 2017. eNeuro. 3(6). PubMed
  718. Teresa Rivera, Candy Haggblom, Sandro Cosconati 2016. Nat Struct Mol Biol. 24:30-39. PubMed
  719. Jager P, et al. 2016. Nat Commun. 7:13579. PubMed
  720. Zeltner N, et al. 2016. Nat Med. 22:1421-1427. PubMed
  721. Gaitán-Peñas H, et al. 2016. Biophys J. 111:1429-1443. PubMed
  722. Zalfa C, et al. 2016. Cell Death Dis. 7:e2331. PubMed
  723. Li S, et al. 2016. Sci Rep. 6:29514. PubMed
  724. Mita T, et al. 2016. J Biol Chem. 291: 4955 - 4965. PubMed
  725. Jia L, et al. 2018. Mol Neurobiol. 55:9089. PubMed
  726. Sun W, et al. 2020. J Clin Invest. 130:345. PubMed
  727. Baek C, et al. 2018. PLoS Biol. 16:e2004162. PubMed
  728. Miyake S et al. 2015. Cell death & disease. 6:e1638 . PubMed
  729. Wang L et al. 2017. The Journal of comparative neurology. 525(13):2915-2928 . PubMed
  730. Stratton JA et al. 2017. eNeuro. 4(3) pii: ENEURO. PubMed
  731. Norsworthy MW et al. 2017. Neuron. 94(6):1112-1120 . PubMed
  732. Brekk OR et al. 2018. Molecular and cellular neurosciences. 95:1-12 . PubMed
  733. Mura M et al. 2019. Stem cell research. 1726:16:00 . PubMed
  734. Jung JS, et al. 2019. J Neurosci. 39:6425. PubMed
  735. Fan D et al. 2019. Elife. 8 pii: e49226. PubMed
  736. Sarah E Pease‐Raissi et al. 2017. Neuron. 96(2):373-386 . PubMed
  737. Sorrells SF, et al. 2019. Nat Commun. 10:2748. PubMed
  738. Lee J, et al. 2018. Invest Ophthalmol Vis Sci. 59:3531. PubMed
  739. Alexander JM et al. 2019. Elife. 8 pii: e41769. PubMed
  740. Hu D, et al. 2019. Acta Neuropathol. 137:939. PubMed
  741. Acosta S, et al. 2018. Genesis. 56:e23212. PubMed
  742. Stallings NR, et al. 2018. Sci Signal. 11:522. PubMed
  743. Diacou R et al. 2018. Cell reports. 25(9):2510-2523 . PubMed
  744. Liu Y et al. 2018. Cell stem cell. 23(5):758-771 . PubMed
  745. Umegaki Y et al. 2018. The Journal of Neuroscience. 38(21):4985-4995 . PubMed
  746. Urrea L, et al. 2018. Mol Neurobiol. 15:1630. PubMed
  747. Hackelberg S, et al. 2017. PLoS One. 10.1371/journal.pone.0180427. PubMed
  748. Stepp MA, et al. 2018. Exp Eye Res. 10:113. PubMed
  749. Merten N et al. 2018. Cell chemical biology. 25(6):775-786 . PubMed
  750. Tandon R et al. 2018. Stem cell research. 33:120-124 . PubMed
  751. Kaur T et al. 2018. The Journal of comparative neurology. 526(5):824-835 . PubMed
  752. Lang C et al. 2019. Cell stem cell. 24(1):93-106 . PubMed
  753. Stylianou N, et al. 2019. Oncogene. 38:913. PubMed
  754. Tiihonen J, et al. 2019. Nat Commun. 10:3933. PubMed
  755. Park KK et al. 2017. The Journal of comparative neurology. 525(2):380-388 . PubMed
  756. Chang CH, et al. 2019. Dev Cell. 48:184. PubMed
  757. Hertz NT et al. 2019. Neuron. 103(3):412-422 . PubMed
  758. Angelim MKSC et al. 2018. Glia. 66(11):2470-2486 . PubMed
  759. Wu J et al. 2017. Cell. 168(3):473-486 . PubMed
  760. Ma S et al. 2017. Developmental cell. 41(4):366-381 . PubMed
  761. Sevilla A et al. 2017. Stem Cell Res. 25:217-220 . PubMed
  762. Crouch EE et al. 2015. The Journal of Neuroscience. 35(11):4528-39 . PubMed
  763. Liu Z, et al. 2017. Stem Cells Dev. 26:177. PubMed
  764. Maslon MM, et al. 2019. EMBO J. 38:e101244. PubMed
  765. Steevens AR, et al. 2019. Development. 146:dev170522. PubMed
  766. Liu W, et al. 2019. Invest Ophthalmol Vis Sci. 60:965. PubMed
  767. Lee JH, et al. 2019. Aging (Albany NY). 11:11541. PubMed
  768. Peng XQ, et al. 2020. Front Cell Neurosci. 0.674305556. PubMed
  769. Dudok J, et al. 2016. Neurosci Res. S0168-0102(16)00002-X. PubMed
  770. Rooney G, et al. 2016. J Neurosci. 36: 142 - 152.. PubMed
  771. Takeo Y, et al. 2016. Sci Rep. 6: 25180. PubMed
  772. Okamoto-Uchida Y, et al. 2016. Sci Rep. 6:37697. PubMed
  773. Wang H, et al. 2017. J Neurochem. 141:347. PubMed
  774. Arber C, et al. 2020. Mol Psychiatry. 25:2919. PubMed
  775. Dementyeva EV, et al. 2021. Stem Cell Research. 53:102348. PubMed
  776. Hung C, et al. 2021. Cell Reports. 35(11):109259. PubMed
  777. Cartoni R, et al. 2016. Neuron. 92(6):1294-1307. PubMed
  778. Schoger E, et al. 2021. Stem Cell Research. 55:102473. PubMed
  779. Valdez C, et al. 2020. Hum Mol Genet. 716:29. PubMed
  780. Tolomeo AM, et al. 2021. Front Cell Neurosci. 602888:15. PubMed
  781. Ornaghi F, et al. 2020. Neurobiol Dis. 134:104667. PubMed
  782. Gangoso E, et al. 2021. Cell. 184:2454. PubMed
  783. Sun Z, et al. 2021. Aging (Albany NY). 13:12587. PubMed
  784. Chen Y, et al. 2021. Nat Methods. 18:528. PubMed
  785. Cast TP, et al. 2021. J Neurosci. 41:392. PubMed
  786. Satoh M, et al. 2021. Int J Mol Sci. 22:. PubMed
  787. Eriksen AZ, et al. 2022. STAR Protoc. 3:101383. PubMed
  788. Kempfle JS, et al. 2021. Front Cell Neurosci. 15:666706. PubMed
  789. Guan Y, et al. 2021. Nat Commun. 12:5078. PubMed
  790. Yao X, et al. 2022. Nat Commun. 13:3883. PubMed
  791. Tasdemir-Yilmaz OE, et al. 2021. Dev Cell. 56:2516. PubMed
  792. Vicentini FA, et al. 2021. Microbiome. 9:210. PubMed
  793. Díaz-García S, et al. 2021. Acta Neuropathol. 142:985. PubMed
  794. Harbuzariu A, et al. 2022. iScience. 25:104407. PubMed
  795. Karpinski BA, et al. 2022. Dis Model Mech. 15:. PubMed
  796. Cai T, et al. 2021. Cell Reports. 36(2):109337. PubMed
  797. van Helden RWJ, et al. 2021. Stem Cell Research. 53:102374. PubMed
  798. Calado SM, et al. 2021. Stem Cell Research. 53:102302. PubMed
  799. Sepehrimanesh M, et al. 2020. American Journal of Physiology-Cell Physiology. 319(4):C771-C780. PubMed
  800. Li C, et al. 2020. eLife. 9:00. PubMed
  801. Fame R, et al. 2016. J Neurosci. 36: 6403 - 6419. PubMed
  802. Long K, et al. 2016. Nat Commun. 7:10354. PubMed
  803. Hindman HB, et al. 2019. Exp Eye Res. 181:49. PubMed
  804. Aravamudhan P, et al. 2020. PLoS Pathog. 16:e1008380. PubMed
  805. Medeiros CS, et al. 2018. J Refract Surg. 34:790. PubMed
  806. Romer–Seibert JS, et al. 2019. FASEB J. 33:3291. PubMed
  807. Cotton JL et al. 2017. Developmental cell. 43(1):35-47 . PubMed
  808. Lin B et al. 2017. Cell stem cell. 21(6):761-774 . PubMed
  809. Richard E et al. 2018. Stem cell research. 29:143-147 . PubMed
  810. Kano M, et al. 2019. Endocrinology. 160:1701. PubMed
  811. Schreurs RRCE, et al. 2019. Immunity. 50:462. PubMed
  812. Ioannou MS et al. 2019. Curr Protoc Cell Biol. 84(1):e95 . PubMed
  813. Poulopoulos A, et al. 2019. Nature. 565:356. PubMed
  814. Sun Z, et al. 2019. Nat Commun. 10:3892. PubMed
  815. Ding D, et al. 2018. J Otol. 13:115. PubMed
  816. Fan L et al. 2018. eLife. 7 pii: e35242. PubMed
  817. Amrita Pathak et al. 2018. Developmental cell. 46(3):376-387 . PubMed
  818. Marlier Q et al. 2018. Cell Death Discov. 4:43 . PubMed
RRID
AB_2313773 (BioLegend Cat. No. 801213)
AB_2313773 (BioLegend Cat. No. 801201)
AB_2313773 (BioLegend Cat. No. 801202)
Disclaimer

Covered by US patents 5,675,063 and 7,429,487. Sold under license from Epitomics.

Antigen Details

Structure
Tubulin β 3 is a 450 amino acid protein with a molecular mass of ~50 kD.
Distribution

Tissue distribution: central and peripheral nervous system.
Cellular distribution: cytosol, cytoskeleton and nucleus.

Function
Tubulin β 3 is the major constituent of microtubules, and plays a critical role in proper axon guidance and maintenance.
Interaction
Alpha tubulin, kinesin and dynein.
Cell Type
Mature Neurons, Neural Stem Cells
Biology Area
Cell Biology, Neuroscience, Neuroscience Cell Markers, Stem Cells
Molecular Family
Microtubules
Antigen References

1. Zhao X, et al. 2017. Med Sci Monit. 22: 3915.
2. Lebok P, et al. 2016. Oncol Lett. 11(3):1987.
3. Du J, et al. 2015. BMC Cancer. 15:536. PubMed
4. Rogue DM., et al. 2013. Clin Exp Metastasis. 31(1): 101.
5. Ploussard G, et al. 2010. Cancer Res. 70(22):9253. PubMed

Gene ID
10381 View all products for this Gene ID
UniProt
View information about Tubulin beta-3 on UniProt.org

Related FAQs

If an antibody clone has been previously successfully used in IBEX in one fluorescent format, will other antibody formats work as well?

It’s likely that other fluorophore conjugates to the same antibody clone will also be compatible with IBEX using the same sample fixation procedure. Ultimately a directly conjugated antibody’s utility in fluorescent imaging and IBEX may be specific to the sample and microscope being used in the experiment. Some antibody clone conjugates may perform better than others due to performance differences in non-specific binding, fluorophore brightness, and other biochemical properties unique to that conjugate.

Will antibodies my lab is already using for fluorescent or chromogenic IHC work in IBEX?

Fundamentally, IBEX as a technique that works much in the same way as single antibody panels or single marker IF/IHC. If you’re already successfully using an antibody clone on a sample of interest, it is likely that clone will have utility in IBEX. It is expected some optimization and testing of different antibody fluorophore conjugates will be required to find a suitable format; however, legacy microscopy techniques like chromogenic IHC on fixed or frozen tissue is an excellent place to start looking for useful antibodies.

Are other fluorophores compatible with IBEX?

Over 18 fluorescent formats have been screened for use in IBEX, however, it is likely that other fluorophores are able to be rapidly bleached in IBEX. If a fluorophore format is already suitable for your imaging platform it can be tested for compatibility in IBEX.

The same antibody works in one tissue type but not another. What is happening?

Differences in tissue properties may impact both the ability of an antibody to bind its target specifically and impact the ability of a specific fluorophore conjugate to overcome the background fluorescent signal in a given tissue. Secondary stains, as well as testing multiple fluorescent conjugates of the same clone, may help to troubleshoot challenging targets or tissues. Using a reference control tissue may also give confidence in the specificity of your staining.

How can I be sure the staining I’m seeing in my tissue is real?

In general, best practices for validating an antibody in traditional chromogenic or fluorescent IHC are applicable to IBEX. Please reference the Nature Methods review on antibody based multiplexed imaging for resources on validating antibodies for IBEX.

Go To Top Version: 7    Revision Date: 01/24/2024

For Research Use Only. Not for diagnostic or therapeutic use.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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