Blog Article

Chemokines are small proteins that regulate chemotaxis or the migration of cells. Some chemokines, like CXCL12 and CXCL13, have homeostatic functions and play a role during basal leukocyte trafficking and stem cell development. Inflammatory chemotactic proteins, like CCL2, CXCL10, and XCL1, are upregulated by an inflammatory stimuli and help to recruit immune cells to a site of infection and can function in wound healing. Given their roles, many chemokines are associated with pathophysiology including tumor metastasis, chronic inflammation, and autoimmune disease.

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Simultaneously quantify up to 13 chemokines in serum, plasma, cell culture supernatants or other biological fluids with one of our LEGENDplex™ chemokine panels for human, mouse, or NHP samples. Only need to look at a subset of chemokines? Mix and match any panel to only look at the targets you need.

Check out our Video Library to watch step-by-step protocol guides. Watch our latest videos to streamline your immunoprecipitation experiments with an epitope-tagged affinity gel or measure soluble proteins, like cytokines and chemokines, with our sandwich ELISA protocol video.

IP with an Affinity Gel

Sandwich ELISA