APC anti-mouse CD38 Antibody

Pricing & Availability
Clone
S21016F (See other available formats)
Regulatory Status
RUO
Other Names
T10
Isotype
Rat IgG2b, κ
S21016F_APC_CD38_Antibody_082223
C57BL/6 mouse splenocytes were stained with anti-mouse B220 FITC and anti-mouse CD38 (clone S21016F) APC or rat IgG2b, κ APC isotype control.
  • S21016F_APC_CD38_Antibody_082223
    C57BL/6 mouse splenocytes were stained with anti-mouse B220 FITC and anti-mouse CD38 (clone S21016F) APC or rat IgG2b, κ APC isotype control.
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Cat # Size Price Quantity Check Availability
165603 25 µg $90.00
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165604 100 µg $310.00
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Description

CD38, also known as T10, is a 45 kD type II transmembrane glycoprotein. It is an ADP-ribosyl hydrolase expressed at variable levels on hematopoietic cells and in some non-hematopoietic tissues (such as brain, muscle, and kidney). By functioning as both a cyclase and a hydrolase, CD38 mediates lymphocyte activation, adhesion, and the metabolism of cADPR and NAADP. CD31 is thought to be a ligand of CD38.

Technical data sheet

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Mouse CD38 transfected cells
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Preparation
The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
Concentration
0.2 mg/mL
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.06 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Red Laser (633 nm)
Application Notes

Clone S21016F can completely block the binding of clone “90” on target cells.

RRID
AB_3068268 (BioLegend Cat. No. 165603)
AB_3068268 (BioLegend Cat. No. 165604)

Antigen Details

Structure
ADP-ribosyl hydrolase, 42 kD
Distribution

B cells, NK cells, T cell subset, brain, muscle, kidney

Function
Regulation of cellular activation/proliferation, adhesion, metabolism of cADPR and NAADP
Ligand/Receptor
CD31, hyaluronic acid
Cell Type
B cells, Lymphocytes, NK cells, T cells
Biology Area
Cell Biology, Costimulatory Molecules, Immuno-Oncology, Immunology
Molecular Family
CD Molecules
Antigen References
  1. Barclay AN, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
  2. Shubinsky G, et al. 1997. Immunity. 7:315-24.
  3. Cesano A, et al. 1998. J Immunol. 160:1106-15.
  4. Cockayne DA, et al. 1998. Blood. 92:1324-33.
Gene ID
12494 View all products for this Gene ID
UniProt
View information about CD38 on UniProt.org
Go To Top Version: 1    Revision Date: 08/22/2023

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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