FITC anti-human CD305 (LAIR1) Antibody

Pricing & Availability
Clone
NKTA255 (See other available formats)
Regulatory Status
RUO
Workshop
HCDM listed
Other Names
LAIR-1 (Leukocyte-associated Ig-like receptor 1)
Isotype
Mouse IgG1, κ
NKTA255_FITC_CD305_Antibody_1_071924-
Human peripheral blood lymphocytes were stained with anti-human CD4 (clone RPA-T4) Pacific Blue™ and anti-human CD305 (LAIR1) (clone NKTA255) FITC (left) or mouse IgG1, κ FITC isotype control (right)
  • NKTA255_FITC_CD305_Antibody_1_071924-
    Human peripheral blood lymphocytes were stained with anti-human CD4 (clone RPA-T4) Pacific Blue™ and anti-human CD305 (LAIR1) (clone NKTA255) FITC (left) or mouse IgG1, κ FITC isotype control (right)
Compare all formats See FITC spectral data
Cat # Size Price Quantity Check Availability
342813 25 tests $171.00
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342814 100 tests $382.00
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Description

CD305, also known as LAIR-1 (leukocyte-associated Ig-like receptor-1), is a 40 kD type I transmembrane glycoprotein. LAIR-1 and LAIR-2 are the only members of the LAIR family in the Ig superfamily. LAIR-1 is an inhibitory molecule characterized by ITIMs in the cytoplasmic domain and collagen ligands. CD305 is expressed on NK cells, T cells, B cells, monocytes, dendritic cells, eosinophils, basophils and mast cells. LAIR-1 functions in the inhibition of cell cytotoxicity, cell activation, proliferation and differentiation.

Technical data sheet

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography and conjugated with FITC under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Application References

(PubMed link indicates BioLegend citation)
  1. Poggi A, et al. 1995. Eur. J. Immunol. 25:369
RRID
AB_3662239 (BioLegend Cat. No. 342813)
AB_3662239 (BioLegend Cat. No. 342814)

Antigen Details

Structure
40 kD type I transmembrane protein, cytoplasmic domain contains ITIM motifs, Ig superfamily
Distribution

NK cells, T cell, B cells, monocytes, dendritic cells, eosinophils, basophils and mast cells

Function
Inhibition of cell cytotoxicity, cell activation, proliferation and differentiation
Ligand/Receptor
collagens
Cell Type
B cells, Basophils, Dendritic cells, Eosinophils, Macrophages, Mast cells, Monocytes, NK cells, T cells
Biology Area
Immunology, Inhibitory Molecules, Innate Immunity
Molecular Family
CD Molecules
Antigen References

1. Meyaard L, et al. 2008. J. Leukoc. Biol. 83:799
2. Lebbink RJ, et al. 2006. J. Exp. Med. 203:1419

Gene ID
3903 View all products for this Gene ID
UniProt
View information about CD305 on UniProt.org
Go To Top Version: 1    Revision Date: 05/22/2024

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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