FITC anti-human TCR Vβ13.1 Antibody

Pricing & Availability
Clone
H131 (See other available formats)
Regulatory Status
RUO
Other Names
T cell receptor Vβ13.1 chain, TCRBV13.1, TCRBV13
Isotype
Mouse IgG2b, κ
H131_FITC_TCR_Vbeta13.1_Antibody_FC_1_080814.jpg
Human peripheral blood lymphocytes were stained with CD3 APC and TCR Vβ13.1 (clone H131) FITC (top) or mouse IgG2b, κ FITC isotype control (bottom).
  • H131_FITC_TCR_Vbeta13.1_Antibody_FC_1_080814.jpg
    Human peripheral blood lymphocytes were stained with CD3 APC and TCR Vβ13.1 (clone H131) FITC (top) or mouse IgG2b, κ FITC isotype control (bottom).
  • H131_FITC_TCR_Vbeta13.1_Antibody_FC_2_080814
Compare all formats See FITC spectral data
Cat # Size Price Quantity Check Availability
362403 25 tests $147.00
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362404 100 tests $323.00
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Description

TCR Vβ13.1 is a variant of the TCR β chain. The receptor is complexed with the TCR α chain and belongs to the immunoglobulin superfamily. It is expressed on a subset of T cells and some T cell clones. Variability in the β chain is generated by Vβ, Dβ, and Jβ gene rearrangement, while variability in the α chain is generated by Vα and Jα rearrangement. TCR Vβ13.1 has been shown to be related to antigen recognition and inflammation as well as diseases, such as HIV and multiple sclerosis.

Technical data sheet

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Mouse T cell hybridoma
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography and conjugated with FITC under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.

Excitation Laser
Blue Laser (488 nm)
Application Notes

Additional reported applications (for the relevant formats of this clone) include: activation of TCR Vβ13.1 expressing cells1.

Application References

(PubMed link indicates BioLegend citation)
  1. Choi YW, et al. 1991. Proc. Natl. Acad. Sci. USA 88:8357.
Product Citations
  1. Montel‐Hagen A et al. 2019. Cell stem cell. 24(3):376-389 . PubMed
RRID
AB_2564031 (BioLegend Cat. No. 362403)
AB_2564031 (BioLegend Cat. No. 362404)

Antigen Details

Structure
Immunoglobulin superfamily
Distribution

Subset of T cells

Function
Antigen recognition, activation of TCR Vβ13.1 bearing T cells
Ligand/Receptor
Peptide bound MHC molecules
Cell Type
T cells
Biology Area
Adaptive Immunity, Immunology
Molecular Family
TCRs
Antigen References

1. Hong J, et al. 1999. J. Immunol. 163:3530.
2. Jason J, et al. 1997. Scand. J. Immunol. 45:81.
3. Chang JC, et al. 1995. Ann. NY. Acad. Sci. 756:370.
4. Miyahara E, et al. 1999. Anticancer Res. 19:2057.
5. Usuku K, et al. 1993. Immunogenetics. 38:193.
6. Bakakos P, et al. 2002. Clin. Exp. Immunol. 129:370.

Gene ID
6957 View all products for this Gene ID
UniProt
View information about TCR Vbeta13.1 on UniProt.org
Go To Top Version: 1    Revision Date: 08/13/2014

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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