- Clone
- S18017D (See other available formats)
- Regulatory Status
- RUO
- Other Names
- FcRI
- Isotype
- Rat IgG2a, κ
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C57BL/6 mouse bone marrow cells were stained with anti-mouse/human CD11b APC and anti-mouse CD64 (FcγRI) (clone S18017D) FITC (left) or rat IgG2a, κ FITC isotype control (right). Data shown was gated on myeloid cells.
| Cat # | Size | Price | Quantity Check Availability | ||
|---|---|---|---|---|---|
| 161007 | 25 µg | $101.00 | |||
| 161008 | 100 µg | $258.00 | |||
CD64 is a 72 kD single chain type I glycoprotein also known as FcγRI and FcRI. CD64 is a member of the immunoglobulin superfamily and is expressed on monocytes/macrophages, dendritic cells, and mast cells. The expression can be upregulated by IFN-γ stimulation. CD64 binds IgG immune complex. It plays a role in antigen capture, phagocytosis of IgG/antigen complexes, and antibody-dependent cellular cytotoxicity (ADCC).
Product Details
- Verified Reactivity
- Mouse, Human
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- Recombinant mouse FcγRI/CD64 (Cat. No. 773806)
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
- Preparation
- The antibody was purified by affinity chromatography and conjugated with FITC under optimal conditions.
- Concentration
- 0.5 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality Tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
-
Blue Laser (488 nm)
- RRID
-
AB_2910337 (BioLegend Cat. No. 161007)
AB_2910337 (BioLegend Cat. No. 161008)
Antigen Details
- Structure
- Ig superfamily, type I glycoprotein, 72 kD
- Distribution
-
Monocytes, macrophages, mast cells, dendritic cells
- Function
- Phagocytosis, ADCC
- Ligand/Receptor
- IgG
- Antigen References
-
1. Schyns J, et al. 2019. Nat. Commun. 3;10(1):3964
2. Langlet C, et al. 2012. J. Immunol. 188 (4) 1751-1760. - Gene ID
- 14129 View all products for this Gene ID
- UniProt
- View information about CD64 on UniProt.org
Other Formats
View All CD64 Reagents Request Custom Conjugation| Description | Clone | Applications |
|---|---|---|
| Purified anti-mouse CD64 (FcγRI) Antibody | S18017D | FC,IHC-F |
| PE anti-mouse CD64 (FcγRI) | S18017D | FC |
| APC anti-mouse CD64 (FcγRI) | S18017D | FC |
| FITC anti-mouse CD64 (FcγRI) | S18017D | FC |
| PE/Fire™ 744 anti-mouse CD64 (FcγRI) | S18017D | FC |
| Spark Blue™ 574 anti-mouse CD64 (FcγRI) (Flexi-Fluor™) | S18017D | FC |
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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Purified anti-mouse CD64 (FcγRI) Antibody
C57BL/6 mouse bone marrow cells were stained with anti-mouse... 
C57BL/6 mouse frozen liver section was fixed with 4% parafor... -
PE anti-mouse CD64 (FcγRI)
C57BL/6 mouse bone marrow cells were stained with anti-mouse... 
Human peripheral blood monocytes were stained with anti-mous... 
Human peripheral blood cells were stained with anti-mouse/hu... -
APC anti-mouse CD64 (FcγRI)
C57BL/6 mouse bone marrow cells were stained with anti-mouse... -
FITC anti-mouse CD64 (FcγRI)
C57BL/6 mouse bone marrow cells were stained with anti-mouse... -
PE/Fire™ 744 anti-mouse CD64 (FcγRI)
C57BL/6 mouse bone marrow cells were stained with anti-mouse... -
Spark Blue™ 574 anti-mouse CD64 (FcγRI) (Flexi-Fluor™)