Pricing & Availability
Technical data sheet
- Regulatory Status
- RUO
- Other Names
- Interferon beta 1
| Cat # | Size | Price | Quantity Check Availability | ||
|---|---|---|---|---|---|
| 449507 | 1 Pre-coated Plate | $655.00 | |||
Description
IFN-β is a type I class of interferon produced by macrophages, dendritic cells, endothelial cells and primarily fibroblasts. It plays a significant antiviral activity role within the innate immune response to infection, cell differentiation and anti-tumor defenses. Once secreted, it binds to a homologous receptor complex and activates the Jak/STAT pathway, resulting in upregulating genes that inhibit viral infection and regulate MHC class 1 antigens. Multiple sclerosis is characterized by a deficiency of IFN beta 1 and is commonly been used as an injectable treatment.
Kit Contents
- Kit Contents
-
- Human IFN-β Pre-Coated Plate
- Human IFN-β Detection Antibody
- Human IFN-β Standard
- Assay Buffer B
- Streptavidin-Polymer HRP
- Wash Buffer (20X)
- Substrate Solution D
- Stop Solution
- Plate Sealers
Product Details
- Verified Reactivity
- Human
- Application
-
ELISA
- Sensitivity
- 0.91 ± 0.16 pg/mL
- Standard Range
- 2.34 - 150 pg/mL
- Materials Not Included
-
- Microwell plates: BioLegend Cat. No. 423501 is recommended
- Wash Buffer: BioLegend Cat. No. 421601 is recommended, or PBS + 0.05% Tween-20
- Stop Solution: BioLegend Cat. No. 423001 is recommended, or acid solution, e.g. 2N H2SO4
- Plate Sealers: BioLegend Cat. No. 423601 is recommended
- PBS (Phosphate-Buffered Saline): 8.0 g NaCl, 1.16 g Na2HPO4 , 0.2 g KH2PO4 , 0.2 g KCl, add deionized water to 1 L; pH to 7.4, 0.2 μm filtered
- Deionized (DI) water
- A microplate reader capable of measuring absorbance at 450 nm
- Adjustable pipettes to measure volumes ranging from 2 μL to 1 mL
- Wash bottle or automated microplate washer
- Log-Log graph paper or software for data analysis
- Tubes to prepare standard dilutions
- Timer
Antigen Details
- Cell Type
- B cells, Dendritic cells, Endothelial cells, Fibroblasts, Macrophages
- Biology Area
- Apoptosis/Tumor Suppressors/Cell Death, Cell Proliferation and Viability, COVID-19, Innate Immunity, Signal Transduction
- Molecular Family
- Cytokines/Chemokines, Innate Immune Signaling
- Gene ID
- 3456 View all products for this Gene ID
- UniProt
- View information about IFN-beta on UniProt.org