- Clone
- 11C3.1 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- Gp34, OX40L, CD134L, CD252, TNFSF4
- Isotype
- Mouse IgG1, κ
-
GM-CSF-stimulated human peripheral blood monocytes (day-3) stained with 11C3.1 PE
| Cat # | Size | Price | Quantity Check Availability | ||
|---|---|---|---|---|---|
| 326307 | 25 tests | $146.00 | |||
| 326308 | 100 tests | $317.00 | |||
OX40 ligand (OX40L) is a 35 kD type II transmembrane protein which belongs to TNF superfamily, also known as gp34, CD252, CD134L or TNFSF4. The OX40 ligand is expressed on activated B cells, activated endothelial cells, mature dendritic cells, activated CTLs, activated mast cells, and airway smooth muscle cells. OX40 ligand interacts with OX40 antigen (CD134) expressed predominantly on activated T cells to regulate T cell proliferation and differentiation, and to enhance immunoglobulin secretion by activated B cells.
Product Details
- Verified Reactivity
- Human
- Reported Reactivity
- African Green
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.
- Excitation Laser
-
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Product Citations
-
- RRID
-
AB_2207272 (BioLegend Cat. No. 326307)
AB_2207272 (BioLegend Cat. No. 326308)
Antigen Details
- Structure
- NGF/TNF superfamily, 35 kD
- Distribution
-
Activated B cells, activated endothelial cells, mature dendritic cells, airway smooth muscle cells
- Function
- B-cell/T-cell interaction, costimulation
- Ligand/Receptor
- OX40 (CD134)
- Cell Type
- B cells, Dendritic cells, Endothelial cells
- Biology Area
- Costimulatory Molecules, Immunology
- Molecular Family
- CD Molecules, Immune Checkpoint Receptors
- Antigen References
-
1. Imura A, et al. 1996. J. Exp. Med. 183:2185.
2. Ohshima Y, et al. 1997. J. Immunol. 159:3838.
3. Ito T, et al. 2005. J. Exp.Med. 202:1213.
4. Ito T, et al. 2006. Proc. Natl. Acad.Sci. USA. 103:13138. - Gene ID
- 7292 View all products for this Gene ID
- UniProt
- View information about CD252 on UniProt.org
Other Formats
View All CD252 Reagents Request Custom Conjugation| Description | Clone | Applications |
|---|---|---|
| Purified anti-human CD252 (OX40L) | 11C3.1 | FC |
| Biotin anti-human CD252 (OX40L) | 11C3.1 | FC |
| PE anti-human CD252 (OX40L) | 11C3.1 | FC |
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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Purified anti-human CD252 (OX40L)
-
Biotin anti-human CD252 (OX40L)
Human endothelial cells (HUVEC) stained with biotinylated 11... -
PE anti-human CD252 (OX40L)
GM-CSF-stimulated human peripheral blood monocytes (day-3) s...