- Clone
- 39D5 (See other available formats)
- Regulatory Status
- RUO
- Workshop
- V NK57
- Other Names
- NCAM-1
- Isotype
- Mouse IgG1, κ
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Human retinoblastoma cell line WERI-RB-1 stained with anti-human CD56 (Subset MSC Marker) (clone 39D5) PE (filled histogram) or mouse IgG1, κ PE isotype control (open histogram).
| Cat # | Size | Price | Quantity Check Availability | ||
|---|---|---|---|---|---|
| 355503 | 25 tests | $134.00 | |||
| 355504 | 100 tests | $335.00 | |||
CD56 is a single transmemberane glycoprotein also known as NCAM (neural cell adhesion molecule). It is a member of the Ig superfamily. The 140 kD isoform is expressed on NK cells and NK-T cells. CD56 is also expressed in the brain (cerebellum and cortex) and at neuromuscular junctions. Certain large granular lymphocyte (LGL) leukemias, small-cell lung carcinomas, neuronal derived tumors, myelomas, and myeloid leukemias also express CD56. CD56 plays a role in homophilic and heterophilic adhesion via binding to itself or heparin sulfate.
Product Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- KG1a cells
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
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FC - Quality tested
- Recommended Usage
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Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.
- Excitation Laser
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Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application Notes
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Clone 39D5 recognizes the epitope of CD56 that is selectively expressed on a subset of mesenchymal stem cells (MSC) population which are CD271bright cells. It does not efficiently recognize natural killer cells.
- Product Citations
-
- RRID
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AB_2561552 (BioLegend Cat. No. 355503)
AB_2561552 (BioLegend Cat. No. 355504)
Antigen Details
- Distribution
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Mesenchymal stem cells
- Cell Type
- Mesenchymal Stem Cells
- Biology Area
- Cell Biology, Costimulatory Molecules, Immunology, Neuroscience, Stem Cells, Synaptic Biology
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
-
1. Battula VL, et al. 2009. Haematologica 94:173.
- Gene ID
- 4684 View all products for this Gene ID
- UniProt
- View information about CD56 on UniProt.org
Other Formats
View All CD56 Reagents Request Custom Conjugation| Description | Clone | Applications |
|---|---|---|
| PE anti-human CD56 (Subset MSC Marker) | 39D5 | FC |
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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PE anti-human CD56 (Subset MSC Marker)
Human retinoblastoma cell line WERI-RB-1 stained with anti-h...