- Clone
- MKB1 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- T cell receptor Vbeta 9
- Isotype
- Mouse IgG1, λ
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Human peripheral blood lymphocytes stained with MKB-1 PE and CD3 APC
| Cat # | Size | Price | Quantity Check Availability | ||
|---|---|---|---|---|---|
| 349204 | 100 tests | $299.00 | |||
Vβ9 T cell receptor (TCR Vβ9) is a variant of the TCR β chain which is heterodimerized with TCR α chain and expressed on a subset of αβ+ T cells. The TCR α/β recognizes peptides presented by the MHC molecules and initiates T cell mediated immune responses. Vβ9+ T cells are activated by the staphylococcal enterotoxin A (SEA).
Product Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.
- Excitation Laser
-
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
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Application References
(PubMed link indicates BioLegend citation) -
- Labrecque N, et al. 1993. J. Exp. Med. 177:1735. (FC)
- Ciurli C, et al. 1998. J. Exp. Med. 187:253. (FC)
- Lavoie PM, et al. 2005. Int. Immunol. 17:931. (FC)
- RRID
-
AB_10640740 (BioLegend Cat. No. 349204)
Antigen Details
- Structure
- Immunoglobulin superfamily, associate with TCR Vα chain and CD3 complex
- Distribution
-
subset of TCR αβ+ T cells
- Function
- Recognition of peptides presented by MHC molecules, responsible for T cell mediated immune response
- Ligand/Receptor
- MHC-peptide complex
- Cell Type
- T cells
- Biology Area
- Adaptive Immunity, Immunology
- Molecular Family
- TCRs
- Antigen References
-
1. Newton DW, et al. 1996. J. Immunol. 157:3988.
2. Marrack P, et al. 2008. Annu. Rev. Immunol. 26:171.
3. Thompson CB. 1995. Immunity 3:531.
4. Krogsgaard M and Davis MM. 2005. Nat. Immunol. 6:239. - Gene ID
- 6957 View all products for this Gene ID
- UniProt
- View information about TCR Vbeta9 on UniProt.org
Other Formats
View All TCR Vβ9 Reagents Request Custom Conjugation| Description | Clone | Applications |
|---|---|---|
| PE anti-human TCR Vβ9 | MKB1 | FC |
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Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
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PE anti-human TCR Vβ9
Human peripheral blood lymphocytes stained with MKB-1 PE and...