PE anti-mouse CD64 (FcγRI) Antibody

Pricing & Availability
Clone
W18349C (See other available formats)
Regulatory Status
RUO
Other Names
FcRI
Isotype
Rat IgG2a, κ
1_W18349C_PE_CD64_Antibody_060722
C57BL/6 mouse bone marrow cells were stained with anti-mouse CD11b APC and anti-mouse CD64 (FcγRI) (clone W18349C) PE (left) or rat IgG2a, κ PE isotype control (right). Data shown was gated on lymphoid and myeloid population.
  • 1_W18349C_PE_CD64_Antibody_060722
    C57BL/6 mouse bone marrow cells were stained with anti-mouse CD11b APC and anti-mouse CD64 (FcγRI) (clone W18349C) PE (left) or rat IgG2a, κ PE isotype control (right). Data shown was gated on lymphoid and myeloid population.
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164403 25 µg $99.00
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Description

CD64 is a 72 kD single chain type I glycoprotein also known as FcγRI and FcRI. CD64 is a member of the immunoglobulin superfamily and is expressed on monocytes/macrophages, dendritic cells, and mast cells. The expression can be upregulated by IFN-γ stimulation. CD64 binds IgG immune complex. It plays a role in antigen capture, phagocytosis of IgG/antigen complexes, and antibody-dependent cellular cytotoxicity (ADCC).

Technical data sheet

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Recombinant mouse FcƳRI/CD64 (aa 25-297)
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Preparation
The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
Concentration
0.2 mg/mL
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
RRID
AB_2922501 (BioLegend Cat. No. 164403)

Antigen Details

Structure
Ig superfamily, type I glycoprotein, 72 kD
Distribution

Monocytes, macrophages, mast cells, dendritic cells

Function
Phagocytosis, ADCC
Ligand/Receptor
IgG
Cell Type
Dendritic cells, Macrophages, Mast cells, Monocytes
Biology Area
Immunology, Innate Immunity
Molecular Family
CD Molecules, Fc Receptors
Antigen References
  1. Tan PS, et al. 2003. J Immunol. 170:2549. (IP)
  2. ​Ingersoll MA, et al. 2010. Blood. 115:e10. (FC)
  3. Ozeri E, et al. 2012. J Immunol. 189:146. 
  4. Richardson ML, et al. 2014. PLoS Negl Trop Dis. 8:2825. 
Gene ID
14129 View all products for this Gene ID
UniProt
View information about CD64 on UniProt.org
Go To Top Version: 2    Revision Date: 05/10/2023

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
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