- Clone
- MR10-2 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- Vβ9 T-cell receptor, T cell receptor beta 9
- Isotype
- Mouse IgG1, κ
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C57BL/6 mouse splenocytes stained with TCR Vβ9 (MR10-2) PE and CD3 (145-2C11) APC
| Cat # | Size | Price | Quantity Check Availability | ||
|---|---|---|---|---|---|
| 139803 | 25 µg | $129.00 | |||
| 139804 | 100 µg | $268.00 | |||
Vβ9 T cell receptor (TCR Vβ9) is a variant of TCR β chain and, along with TCR α chain, forms the TCR heterodimer. In association with the CD3 complex, TCR α/β is responsible for antigen recognition through interaction with MHC-peptide complex to initiate T cell-mediated immune responses. Murine Vβ9 cells recognize the Mtv-43, Mtv-44, and exogenous MMTV (SW) Mls-1 superantigens.Mice bearing a and c haplotypes have Vβ9 gene deletion.
Product Details
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Mouse T-cell hybridoma 2BR18
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
- Concentration
- 0.2 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.06 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
-
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
-
Application References
(PubMed link indicates BioLegend citation) -
- Utsunomiya Y, et al. 1991. Eur. J. Immunol. 21:1007. (FC)
- Product Citations
-
- RRID
-
AB_10641563 (BioLegend Cat. No. 139803)
AB_10641563 (BioLegend Cat. No. 139804)
Antigen Details
- Structure
- Member of the immunoglobulin superfamily, Vβ9 is a variant of the TCR β chain which associates with the TCR α chain to form the TCR heterodimer.
- Distribution
-
Subset of TCR αβ+ T cells
- Function
- Recognition of peptides presented by MHC molecules, responsible for T cell mediated immune responses.
- Ligand/Receptor
- MHC-peptide complex
- Cell Type
- T cells
- Biology Area
- Adaptive Immunity, Immunology
- Molecular Family
- TCRs
- Antigen References
-
1. Ortman RA, et al. 1994. J. Immunol. 152:4175.
2. Niimi N, et al. 1994. Immunogenetics 40:312.
3. Pied s, et al. 1997. Int. Immunol. 9:17. - Gene ID
- 21577 View all products for this Gene ID
- UniProt
- View information about TCR Vbeta9 on UniProt.org
Other Formats
View All TCR Vβ9 Reagents Request Custom Conjugation| Description | Clone | Applications |
|---|---|---|
| PE anti-mouse TCR Vβ9 | MR10-2 | FC |
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Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
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PE anti-mouse TCR Vβ9
C57BL/6 mouse splenocytes stained with TCR Vβ9 (MR10-2) PE a...