- Clone
- BL37.2 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- TCRBV1S1, TCRBV9
- Isotype
- Rat IgG1, κ
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Human peripheral blood lymphocytes were stained with CD3 APC and anti-human TCR Vβ1 (clone BL37.2 PerCP/Cyanine5.5 (left) or rat IgG1, κ PerCP/Cyanine5.5 isotype control (right).
| Cat # | Size | Price | Quantity Check Availability | ||
|---|---|---|---|---|---|
| 360104 | 100 tests | $382.00 | |||
TCR Vβ1 is a variant of the TCR Vβ chain that is expressed by a subset of αβ+ T cells. Aberrant expression of TCR Vβ chains has been associated with infection and cancer. TCR Vβ1 is reported to be preferably used by autoreactive T cells in a model of autoimmune thyroiditis and diabetes. Skewing of TCR Vβ repertoire to Vβ1 and Vβ9 has also been reported in patients with multiple sclerosis, reactive arthritis, and Kawasaki disease.
Product Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- Rat cell line RBL-2H3 transfected with human TCR-VB1
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with PerCP/Cyanine5.5 under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
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FC - Quality tested
- Recommended Usage
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Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.
* PerCP/Cyanine5.5 has a maximum absorption of 482 nm and a maximum emission of 690 nm. - RRID
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AB_2562497 (BioLegend Cat. No. 360104)
Antigen Details
- Structure
- Disulfide-linked 80 kD heterodimer consisting of an α and β chain
- Distribution
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Subset of αβ+ T cells
- Function
- Recognize antigens bound to MHC molecules
- Ligand/Receptor
- Antigen bound MHC molecules
- Cell Type
- T cells
- Biology Area
- Adaptive Immunity, Immunology
- Molecular Family
- TCRs
- Antigen References
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1. Cihak J, et al. 1991. Proc. Natl. Acad. Sci. 88:10951.
2. Wei S, et al. 1994. Immunogenetics. 40:27.
3. Dunon D, et al. 1994. EMBO J. 13:808. - Gene ID
- 6957 View all products for this Gene ID
- UniProt
- View information about TCR Vbeta1 on UniProt.org
Other Formats
View All TCR Vβ1 Reagents Request Custom Conjugation| Description | Clone | Applications |
|---|---|---|
| PerCP/Cyanine5.5 anti-human TCR Vβ1 | BL37.2 | FC |
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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PerCP/Cyanine5.5 anti-human TCR Vβ1
Human peripheral blood lymphocytes were stained with CD3 APC...