Purified anti-human CD38 Antibody

Pricing & Availability
Clone
S17015A (See other available formats)
Regulatory Status
RUO
Other Names
HB7, T10, ADP-ribosyl cyclase
Isotype
Mouse IgG1, κ
S17015A_PURE_CD38_Antibody_020320.png
Human peripheral blood lymphocytes were stained with purified CD38 (clone S17015A) (filled histogram) or mouse IgG1, κ isotype control (open histogram), followed by anti-mouse IgG PE.
  • S17015A_PURE_CD38_Antibody_020320.png
    Human peripheral blood lymphocytes were stained with purified CD38 (clone S17015A) (filled histogram) or mouse IgG1, κ isotype control (open histogram), followed by anti-mouse IgG PE.
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Cat # Size Price Quantity Check Availability
397102 100 µg $124.00
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Description

CD38 is a 45 kD type II transmembrane glycoprotein also known as T10. It is an ADP-ribosyl hydrolase expressed at variable levels on hematopoietic cells and in some non-hematopoietic tissues (such as brain, muscles, and kidney). In humans, it is expressed at high levels on plasma cells and activated T and B cells. By functioning as both a cyclase and a hydrolase, CD38 mediates lymphocyte activation, adhesion, and the metabolism of cADPR and NAADP. CD31 is the ligand of CD38.

Technical data sheet

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Human CD38 transfectants
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/mL
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

S17015A does not cross-block binding of clones HIT2, HB-7 or S17015F also raised against human CD38 based on in-house testing.

RRID
AB_2832763 (BioLegend Cat. No. 397102)

Antigen Details

Structure
ADP-ribosyl cyclase, ectoenzyme, type II glycoprotein, 45 kD
Distribution

T cells, B cells, NK, myeloid, plasma, and dendritic cells

Function
Ecto-ADP-ribosyl cyclase, calcium signaling, cell activation
Ligand/Receptor
CD31, hyaluronic acid
Cell Type
B cells, Dendritic cells, NK cells, Plasma cells, T cells
Biology Area
Cell Adhesion, Cell Biology, Immunology
Antigen References
  1. Ferrero E, et al. 1999. J Leukoc Biol. 65:151.
  2. Lund F, et al. 1995. Immunol Today. 16:469.
Gene ID
952 View all products for this Gene ID
UniProt
View information about CD38 on UniProt.org
Go To Top Version: 1    Revision Date: 02/03/2020

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
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