- Clone
- S22015B (See other available formats)
- Regulatory Status
- RUO
- Other Names
- Thy-1, Thy1
- Isotype
- Mouse IgG1, κ
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HEL cells (human erythroleukemia cell line) were stained with purified anti-human CD90 (Thy1) (clone S22015B) (filled histogram) or purified mouse IgG1, κ isotype control (open histogram), followed by goat anti-mouse IgG PE.
| Cat # | Size | Price | Quantity Check Availability | ||
|---|---|---|---|---|---|
| 389802 | 100 µg | $170.00 | |||
CD90, also known as Thy-1, is a 25-35 kD GPI-anchored protein. It belongs to the Ig superfamily. Human CD90 is expressed on neuronal cells, a subset of CD34+ cells, a subset of fetal liver cells and fetal thymocytes, fibroblasts, activated endothelial cells, and some leukemia cell lines. CD34+CD90+ cells are primitive hematopoietic stem cells. It has been reported that Thy-1 binds with β2 and β3 integrins and plays bimodal roles in the regulation of cell adhesion and neurite outgrowth, and inhibits hematopoietic stem cells proliferation and differentiation.
Product Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Human CD90-transfected cells
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
- Recommended Usage
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Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
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Clone S22015B is able to completely block the binding of clone 5E10 on target cells.
Clone S22015B does not block the binding of clone S22015F on target cells. - RRID
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AB_3106021 (BioLegend Cat. No. 389802)
Antigen Details
- Structure
- 25-35 kD glycoprotein, Ig superfamily
- Distribution
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Subset of CD34+ hematopoietic stem cells, subset of fetal thymocytes, subset of fetal liver cells, fibroblast, activated endothelial cells, neurons, and some leukemia cell lines
- Function
- Cell adhesion
- Cell Type
- Endothelial cells, Fibroblasts, Hematopoietic stem and progenitors, Leukemia, Neurons, Thymocytes
- Biology Area
- Cell Adhesion, Neurodegeneration, Neuroscience, Stem Cells
- Molecular Family
- CD Molecules
- Antigen References
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- McKenzie JL, et al. 1981. J Immunol. 126:843-50.
- Avalos AM, et al. 2002. Biol Res. 35:231-8.
- Wetzel A, et al. 2004. J Immunol. 172:3850-9.
- Gene ID
- 7070 View all products for this Gene ID
- UniProt
- View information about CD90 on UniProt.org
Other Formats
View All CD90 Reagents Request Custom Conjugation| Description | Clone | Applications |
|---|---|---|
| Purified anti-human CD90 (Thy1) | S22015B | FC |
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Purified anti-human CD90 (Thy1)
HEL cells (human erythroleukemia cell line) were stained wit...