- Clone
- BL28595 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- Inhibin Subunit Alpha, Inhibin Alpha Chain, Inhibin Alpha Subunit, A-Inhibin Subunit, Inhibin, Alpha, inhibin
- Isotype
- Mouse IgG2a, κ
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Western blot of purified anti-Inhibin α antibody (clone BL28595). Lane 1: Molecular weight marker; Lane 2: 20 µg of human brain lysate; Lane 3: 20 µg of mouse brain lysate; Lane 4: 20 µg of rat brain lysate. The blot was incubated with 0.5 µg/mL of the primary antibody overnight at 4°C, followed by incubation with HRP-labeled goat anti-mouse IgG (Cat. No. 405306). Enhanced chemiluminescence was used as the detection system.
| Cat # | Size | Price | Quantity Check Availability | ||
|---|---|---|---|---|---|
| 859501 | 25 µg | $106.00 | |||
Inhibin α (INHA) interacts with INHBA or INHBB to form a dimeric inhibitor for Follicle-stimulating hormone secretion. Due to its role in regulating gonadal stromal cell proliferation, it has been implicated in cancer research, and has been used as a marker of ovarian cancer. Clinically, INHA levels is also part of the prenatal quad screen during second trimester as preliminary indicator of Down syndrome.
Product Details
- Verified Reactivity
- Human, Mouse, Rat
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Recombinant Inhibin A (INHA) expressed in E. coli.
- Formulation
- 0.01 M PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- Store at 4°C for up to 3 months. For longer term storage aliquot into small volumes and store at -20°C.
- Application
-
WB - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.5 - 2.0 µg per ml. It is recommended that the reagent be titrated for optimal performance for each application.
- RRID
-
AB_2801229 (BioLegend Cat. No. 859501)
Antigen Details
- Structure
- INHA is a 366 amino acid protein with an apparent molecular mass of ~ 40 kD.
- Distribution
-
Tissue Distribution: Adrenal gland and Testis
Cellular Distribution: Extracellular and plasma membrane - Function
- INHA regulates hypothalamic, pituitary, and gonadal hormone secretion.
- Interaction
- Forms dimer with INHBA
- Biology Area
- Cancer Biomarkers, Neuroscience
- Molecular Family
- Hormones
- Antigen References
-
- Robertson DM, et al. 2007. Cancer Letters. 249(1):14
- Kommoss F, et al. 2019. Pathologe. 40(1):61
- Lee Y, et al. 2019. Obes Surg. 29(1):334
- Gene ID
- 3623 View all products for this Gene ID 16322 View all products for this Gene ID 24504 View all products for this Gene ID
- UniProt
- View information about Inhibin alpha on UniProt.org
Other Formats
View All Inhibin α Reagents Request Custom Conjugation| Description | Clone | Applications |
|---|---|---|
| Purified anti-Inhibin α | BL28595 | WB |
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
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Purified anti-Inhibin α
Western blot of purified anti-Inhibin α antibody (clone BL28...