Purified anti-mouse CD14 (Maxpar® Ready) Antibody

Pricing & Availability
Clone
Sa14-2 (See other available formats)
Regulatory Status
RUO
Other Names
LPS receptor
Isotype
Rat IgG2a, κ
Sa14-2_Purified_CD14_Cytof_1_060314.jpg
MC/9 (top) or J774A.1 (bottom) mouse cell lines stained with 156Gd anti-CD14 (Sa14-2). Data provided by DVS Sciences.
  • Sa14-2_Purified_CD14_Cytof_1_060314.jpg
    MC/9 (top) or J774A.1 (bottom) mouse cell lines stained with 156Gd anti-CD14 (Sa14-2). Data provided by DVS Sciences.
  • Sa14-2_Purified_CD14_Cytof_2_060314.jpg
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Cat # Size Price Quantity Check Availability
123321 100 µg $118.00
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Description

CD14 is a 53-55 kD glycosylphosphatidylinositol (GPI)-linked membrane glycoprotein also known as LPS receptor. CD14 is expressed on macrophages, dendritic cells, Kupffer cells, hepatocytes, and granulocytes. As a high-affinity receptor for LPS-LBP (LPS-binding protein) complex, CD14, in association with Toll-like Receptor 4 (TLR4) or 2 (TLR2), is involved in the clearance of gram-negative pathogens.

Technical data sheet

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Mouse thymus or spleen
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and EDTA.
Preparation
The antibody was purified by affinity chromatography.
Concentration
1.0 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested
CyTOF® - Verified
Recommended Usage

This product is suitable for use with the Maxpar® Metal Labeling Kits. For metal labeling using Maxpar® Ready antibodies, proceed directly to the step to Partially Reduce the Antibody by adding 100 µl of Maxpar® Ready antibody to 100 µl of 4 mM TCEP-R in a 50 kDa filter and continue with the protocol. Always refer to the latest version of Maxpar® User Guide when conjugating Maxpar® Ready antibodies.

Additional Product Notes

Maxpar® is a registered trademark of Standard BioTools Inc.

RRID
AB_2563720 (BioLegend Cat. No. 123321)

Antigen Details

Structure
GPI-linked membrane glycoprotein, 53-55 kD
Distribution

macrophages, dendritic cells, kupffer cells, hepatocytes

Function
LPS receptor, clearance of Gram-negative pathogens
Ligand/Receptor
LPS
Cell Type
Dendritic cells, Macrophages
Biology Area
Cell Biology, Immunology, Innate Immunity, Neuroinflammation, Neuroscience
Molecular Family
Adhesion Molecules, CD Molecules
Antigen References

1. Stocks S, et al. 1990. Biochem. J. 268:275.
2. Akashi S, et al. 2003. J. Exp. Med. 198:1035.
3. Matsuura K, et al. 1994. J. Exp. Med. 179:1671.
4. Liu S, et al. 1998. Infect. Immun. 66:5089.

Gene ID
12475 View all products for this Gene ID
UniProt
View information about CD14 on UniProt.org
Go To Top Version: 2    Revision Date: 07/21/2022

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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