- Clone
- QA19A45 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- αM integrin, Mac-1 α subunit, Mol, CR3, and Ly-40
- Isotype
- Rat IgG2a, κ
-
C57BL/6 mouse bone marrow myeloid cells were stained with anti-mouse Ly-6G/Ly-6C (Gr-1) FITC and purified anti-mouse/human CD11b recombinant (clone QA19A45) (left), or rat IgG2a, κ isotype control (right), followed by anti-rat IgG PE.
| Cat # | Size | Price | Quantity Check Availability | ||
|---|---|---|---|---|---|
| 163702 | 100 µg | $54.00 | |||
CD11b is a member of the integrin family, primarily expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b non-covalently associates with CD18 (β2 integrin) to form Mac-1. Mac-1 plays an important role in cell-cell interaction by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen.
Product Details
- Verified Reactivity
- Mouse, Human
- Antibody Type
- Recombinant
- Host Species
- Rat
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.
- RRID
-
AB_2892339 (BioLegend Cat. No. 163702)
Antigen Details
- Structure
- Integrin family, associates with integrin β2 (CD18), 170 kD
- Distribution
-
Granulocytes, monocytes/macrophages, dendritic cells, NK cells, subsets of T and B cells.
- Function
- Adhesion, chemotaxis
- Ligand/Receptor
- ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, fibrinogen
- Antigen References
-
1. Barclay A, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Springer TA. 1994. Cell 76:301.
3. Coxon A, et al. 1996. Immunity 5:653. - Gene ID
- 16409 View all products for this Gene ID 3684 View all products for this Gene ID
- UniProt
- View information about CD11b on UniProt.org
Other Formats
View All CD11b Reagents Request Custom Conjugation| Description | Clone | Applications |
|---|---|---|
| Purified anti-mouse/human CD11b Recombinant Antibody | QA19A45 | FC |
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
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Purified anti-mouse/human CD11b Recombinant Antibody
C57BL/6 mouse bone marrow myeloid cells were stained with an...