Stem Cell Research Areas

Embryonic (ESCs) and Induced Pluripotent Stem Cells (iPSCs)

Embryonic stem cells (ESCs) are derived from the inner cell mass of the blastocyst and are capable of differentiating into each of the three primary germ layers: ectoderm, mesoderm, or endoderm. Due to the limited availability of human ESCs, researchers devised a method of generating pluripotent stem cells from adult cells through genetic reprogramming. These cells are referred to as induced pluripotent stem cells (iPSCs) and hold significant promise in the field of regenerative medicine and treatment of several diseases and disorders.

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Hematopoietic Stem Cells (HSCs)

Hematopoietic stem cells (HSCs) are bone marrow-derived multipotent stem cells that give rise to all the blood cell types from the myeloid and lymphoid lineages including monocytes and macrophages, neutrophils, basophils, eosinophils, erythrocytes, megakaryocytes/platelets, dendritic cells, T cells, B cells, and NK cells.

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Mesenchymal Stem Cells (MSCs)

Mesenchymal stem cells (MSCs) are multipotent stem cells derived from the mesoderm that can differentiate into a variety of cell types including: osteoblasts, chondrocytes, myocytes, and adipocytes. MSCs are now widely studied to determine their possible utility in tissue engineering, wound healing and other conditions in which regenerated cells can improve or resolve disease.

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Neural Stem Cells (NSCs)

Neural stem cells (NSCs) are multipotent cells which give rise to neurons, astrocytes, and oligodendrocytes of the central nervous system. Neural stem cells are being researched as potential therapeutics for several neurodegenerative diseases including Parkinson’s disease, Huntington’s disease, and multiple sclerosis.

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