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Alexa Fluor® 647 anti-mouse JAML Antibody

Pricing & Availability
Clone
4E10 (See other available formats)
Regulatory Status
RUO
Other Names
AMICA
Isotype
Armenian Hamster IgG
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Product Citations
publications
4E10_A647_011409.jpg
BALB/c bone marrow cells stained with 4E10 Alexa Fluor® 647 ( gated on myeloid cell population)
  • 4E10_A647_011409.jpg
    BALB/c bone marrow cells stained with 4E10 Alexa Fluor® 647 ( gated on myeloid cell population)
  • B_4E10_A647_011909.jpg
    C57BL/6 peripheral blood granulocytes stained with 4E10 Alexa Fluor® 647 and RB6-8C5 (Gr-1) Alexa Fluor® 488
Compare all formats See Alexa Fluor® 647 spectral data
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128506 100 µg 235€
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Description

JAML is a type I integral transmembrane protein with 2 extracellular IgSF domains characteristic of many proteins implicated in cell to cell interactions.JAML is primarily express on granulocytes and reported to be involved in neutrophil migration across tight junctions by its adhesive interaction with epithelial Coxsackie and adenovirus receptor (CAR).

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Armenian Hamster
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 647 under optimal conditions.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per 106 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for other applications.

* Alexa Fluor® 647 has a maximum emission of 668 nm when it is excited at 633nm / 635nm.
Alexa Fluor® and Pacific Blue™ are trademarks of Life Technologies Corporation.

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Excitation Laser
Red Laser (633 nm)
Application References
  1. Zen K, et al. 2005. Mol Biol Cell 16:2694
Product Citations
  1. Edwards SC, et al. 2023. J Exp Med. 220: . PubMed
  2. Tan L, et al. 2019. Cell Rep. 27:3657. PubMed
RRID
AB_1186014 (BioLegend Cat. No. 128506)

Antigen Details

Structure
Type I integral transmembrane protein with 2 extracellular IgSF domains characteristic of proteins implicated in cell-cell interactions, a transmembrane segament and an intracellular tail.
Distribution

Primarily on granulocytes

Ligand/Receptor
Epithelial Coxsackie and adenovirus receptor (CAR)
Cell Type
Granulocytes, Neutrophils
Biology Area
Immunology
Molecular Family
Adhesion Molecules
Antigen References

1. Moog-Lutz C et al. 2003. Blood 102 :3371

Gene ID
270152 View all products for this Gene ID
UniProt
View information about JAML on UniProt.org
Go To Top Version: 2    Revision Date: 06.27.2014

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

BioLegend, the BioLegend logo, and all other trademarks are property of BioLegend, Inc. or their respective owners, and all rights are reserved.

 

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Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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