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FITC anti-human CD305 (LAIR1) Antibody

Pricing & Availability
Clone
NKTA255 (See other available formats)
Regulatory Status
RUO
Workshop
HCDM listed
Other Names
LAIR-1 (Leukocyte-associated Ig-like receptor 1)
Isotype
Mouse IgG1, κ
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Product Citations
publications
NKTA255_FITC_CD305_Antibody_1_071924-
Human peripheral blood lymphocytes were stained with anti-human CD4 (clone RPA-T4) Pacific Blue™ and anti-human CD305 (LAIR1) (clone NKTA255) FITC (left) or mouse IgG1, κ FITC isotype control (right)
  • NKTA255_FITC_CD305_Antibody_1_071924-
    Human peripheral blood lymphocytes were stained with anti-human CD4 (clone RPA-T4) Pacific Blue™ and anti-human CD305 (LAIR1) (clone NKTA255) FITC (left) or mouse IgG1, κ FITC isotype control (right)
Compare all formats See FITC spectral data
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342813 25 tests 137€
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342814 100 tests 306€
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Description

CD305, also known as LAIR-1 (leukocyte-associated Ig-like receptor-1), is a 40 kD type I transmembrane glycoprotein. LAIR-1 and LAIR-2 are the only members of the LAIR family in the Ig superfamily. LAIR-1 is an inhibitory molecule characterized by ITIMs in the cytoplasmic domain and collagen ligands. CD305 is expressed on NK cells, T cells, B cells, monocytes, dendritic cells, eosinophils, basophils and mast cells. LAIR-1 functions in the inhibition of cell cytotoxicity, cell activation, proliferation and differentiation.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography and conjugated with FITC under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Application References
  1. Poggi A, et al. 1995. Eur. J. Immunol. 25:369
RRID
AB_3662239 (BioLegend Cat. No. 342813)
AB_3662239 (BioLegend Cat. No. 342814)

Antigen Details

Structure
40 kD type I transmembrane protein, cytoplasmic domain contains ITIM motifs, Ig superfamily
Distribution

NK cells, T cell, B cells, monocytes, dendritic cells, eosinophils, basophils and mast cells

Function
Inhibition of cell cytotoxicity, cell activation, proliferation and differentiation
Ligand/Receptor
collagens
Cell Type
B cells, Basophils, Dendritic cells, Eosinophils, Macrophages, Mast cells, Monocytes, NK cells, T cells
Biology Area
Immunology, Inhibitory Molecules, Innate Immunity
Molecular Family
CD Molecules
Antigen References

1. Meyaard L, et al. 2008. J. Leukoc. Biol. 83:799
2. Lebbink RJ, et al. 2006. J. Exp. Med. 203:1419

Gene ID
3903 View all products for this Gene ID
UniProt
View information about CD305 on UniProt.org
Go To Top Version: 1    Revision Date: 05.22.2024

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

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Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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