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PE anti-human CD231 (TALLA) Antibody

Pricing & Availability
Clone
SN1a (M3-3D9) (See other available formats)
Regulatory Status
RUO
Workshop
VII 70397
Other Names
kT-cell acute lymphoblastic leuemia antigen, TALLA-1, transmembrane 4 superfamily, TM4SF2
Isotype
Mouse IgG1, κ
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Product Citations
publications
SN1a_PE_082808.jpg
Human T lymphoblastic leukemia cell line, Jurkat, stained with SN1a (M3-3D9) PE
  • SN1a_PE_082808.jpg
    Human T lymphoblastic leukemia cell line, Jurkat, stained with SN1a (M3-3D9) PE
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329406 100 tests 215€
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Description

CD231 is 150 kD (28-45 kD reduced) cell surface glycoprotein belonging to the Transmembrane 4 Superfamily (TM4SF also known as tetraspanins). It was originally described as T-cell Acute Lymphoblastic Leukemia Antigen (TALLA or TALLA-1). CD231 is expressed on T-cell acute lymphoblastic leukemia, neuroblastoma cells, skeletal muscle, spleen and normal brain neuron. CD231 plays a role in integrin-mediated migration, however, its biological function is not fully clear yet.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Human
Reported Reactivity
African Green, Baboon, Cynomolgus
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
isolated human CD231 antigen
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application Notes

Additional reported applications (for the relevant formats) include: immunoprecipitation1, immunohistochemical staining of acetone-fixed frozen tissue sections1, immunofluorescence2

Application References
  1. Matsuzaki H and Seon BK. 1987. Cancer Res. 47:4283.
  2. Seon BK, et al. 1983. Proc. Natl. Acad. Sci. USA. 80:845.
RRID
AB_2213452 (BioLegend Cat. No. 329406)

Antigen Details

Distribution

T-cell acute lymphoblastic leukemia, skeletal muscle, spleen, neuroblastoma cells and normal brain neuron

Cell Type
Leukemia, Neurons
Biology Area
Immunology
Molecular Family
CD Molecules
Antigen References

1. Matsuzaki H and Seon BK. 1987. Cancer Res. 47:4283.
2. Seon BK, et al. 1983. Proc. Natl. Acad. Sci. USA. 80:845.
3. Hara H and Seon BK. 1986. Proc. Natl. Acad. Sci. USA 84:3390.

Gene ID
7102 View all products for this Gene ID
UniProt
View information about CD231 on UniProt.org

Related FAQs

What type of PE do you use in your conjugates?
We use R-PE in our conjugates.
Go To Top Version: 1    Revision Date: 11.30.2012

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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