- Clone
- K56A/50 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- Peripheral plasma membrane protein CASK, LIN2
- Previously
-
Covance Catalog# MMS-5128
- Isotype
- Mouse IgG1, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
Cat # | Size | Price | Quantity Check Availability | Save | ||
---|---|---|---|---|---|---|
830601 | 100 µL | 132€ |
Calcium/Calmodulin-Dependent Serine Protein Kinase (CASK) is a multidomain scaffolding protein with a role in synaptic transmembrane protein anchoring and ion channel trafficking. It contributes to neural development and regulation of gene expression via interaction with the transcription factor TBR1. It binds to cell-surface proteins, including amyloid precursor protein, neurexins and syndecans.
Product DetailsProduct Details
- Verified Reactivity
- Human, Mouse, Rat
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- This monoclonal antibody was raised against a fusion protein corresponding to amino acids 318-415 of rat CASK.
- Formulation
- Phosphate-buffered solution.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 1 mg/ml
- Storage & Handling
- This antibody should be handled aseptically as it is free of preservatives such as Sodium Azide. Store this antibody undiluted between 2°C and 8°C. Please note the storage condition for this antibody has been changed from -20°C to between 2°C and 8°C. You can also check the vial label or CoA to find the proper storage conditions.
- Application
-
WB - Quality tested
IHC-P - Verified - Recommended Usage
-
Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 1.0 - 10.0 µg per ml. For immunohistochemical staining of formalin-fixed paraffin-embedded tissue sections, a concentration of 10.0 µg/ml is suggested. It is recommended that the reagent be titrated for optimal performance for each application.
- Application References
-
- Hsueh YP, et al. 1999. J Neurosci. 19:7415.
- RRID
-
AB_2564940 (BioLegend Cat. No. 830601)
Antigen Details
- Structure
- Expected MW: 100 kD
- Biology Area
- Cell Biology, Neuroscience, Signal Transduction, Synaptic Biology
- Molecular Family
- Presynaptic proteins
- Gene ID
- 29647 View all products for this Gene ID
- UniProt
- View information about CASK on UniProt.org
Related Pages & Pathways
Pages
Related FAQs
Other Formats
View All CASK Reagents Request Custom ConjugationDescription | Clone | Applications |
---|---|---|
Purified anti-CASK | K56A/50 | WB,IHC-P |
Compare Data Across All Formats
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Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
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