- Clone
- 5F3 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- 17b-HSD10, ABAD, CAMR, DUPXp11.22, HADH2, HCD2, MHBD, MRPP2, MRX17, MRX31, MRXS10, SCHAD, SDR5C1, HSD17B10, HSD-10, 3-hydroxyacyl-CoA dehydrogenase type-2, AB-binding alcohol dehydrogenase, mitochondrial ribonuclease P protein 2
- Previously
-
Signet Catalog# 9770-02
Signet Catalog# 9770-05
Signet Catalog# 9770-10
Covance Catalog# SIG-39770
- Isotype
- Mouse IgG1, λ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
The clone 5F3 recognizes the endogenous HSD17B10 protein in extracts from cells with virtually no cross-reactivity to other human proteins in immunoblots and ELISA assays. HSD17B10 is an intracellular 27kD polypeptide which appears to be up regulated in the brains of Alzheimer’s disease patients and has been associated with amyloid beta neurotoxicity. Cross-reactivity to mouse or other species has not been tested.
Product DetailsProduct Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- This antibody was generated against recombinant, full-length human HSD17B10 protein.
- Formulation
- Phosphate-buffered solution; no preservatives or carrier proteins.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 1 mg/ml
- Storage & Handling
- This antibody should be handled aseptically as it is free of preservatives such as Sodium Azide. Store this antibody undiluted between 2°C and 8°C. Please note the storage condition for this antibody has been changed from -20°C to between 2°C and 8°C. You can also check the vial label or CoA to find the proper storage conditions.
- Application
-
IHC-P - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by formalin-fixed paraffin-embedded immunohistochemical staining. For immunohistochemistry, a concentration range of 1.0 - 10 µg/ml is suggested. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
-
Clone 5F3 recognizes the recombinant human HSD17B10 protein (27kD) and is an excellent mitochondrial marker.
Please note that the name of this product has changed from Purified anti-ERAB Antibody to Purified anti-HSD17B10 Antibody. - Application References
-
- He XY, et al. 2000. Biochim BioPhys Acta. 1484 (2-3):267-77.
- Yan SD, et al. 1999. J Biol Chem. 274(4):2145-56.
- Oppermann UC, et al. 1999. FEBS Lett. 451(3):238-42.
- Sambamurti K & Lahiri DK. 1998. Biochem Biophys Res Commun. 249(2):546-9.
- Yan SD, et al. 1997. Nature. 389(6652):689-95.
- Furuta S, et al. 1997. Biochim BioPhys Acta. 1350(3):317-24.
- RRID
-
AB_2564990 (BioLegend Cat. No. 834405)
AB_2564990 (BioLegend Cat. No. 834404)
AB_2564990 (BioLegend Cat. No. 834402)
Antigen Details
- Biology Area
- Cell Biology, Mitochondrial Function, Neuroscience, Neuroscience Cell Markers, Signal Transduction
- Molecular Family
- Mitochondrial Markers
- Gene ID
- 3028 View all products for this Gene ID
- UniProt
- View information about HSD17B10 on UniProt.org
Related Pages & Pathways
Pages
Related FAQs
Other Formats
View All HSD17B10 Reagents Request Custom ConjugationDescription | Clone | Applications |
---|---|---|
Purified anti-HSD17B10 | 5F3 | IHC-P |
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
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