Loading...

Purified anti-mouse CD16/32 Antibody

Pricing & Availability
Clone
93 (See other available formats)
Regulatory Status
RUO
Other Names
Fcγ R III/II, Ly-17
Isotype
Rat IgG2a, λ
Ave. Rating
Submit a Review
Product Citations
publications
93_purified_051906
C57BL/6 mouse splenocytes stained with purified 93, followed by anti-rat IgGs FITC
  • 93_purified_051906
    C57BL/6 mouse splenocytes stained with purified 93, followed by anti-rat IgGs FITC
Compare all formats
Cat # Size Price Quantity Check Availability Save
101301 50 µg 29€
Check Availability


Need larger quantities of this item?
Request Bulk Quote
101302 500 µg 92€
Check Availability


Need larger quantities of this item?
Request Bulk Quote
Description

CD16 is low affinity IgG Fc receptor III (FcR III) and CD32 is FcR II. CD16/CD32 are expressed on B cells, monocytes/macrophages, NK cells, granulocytes, mast cells, and dendritic cells. The Fc receptors bind antibody-antigen immune complexes and mediate adaptive immune responses.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Sorted pre-B cells
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The CD16/32 antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested
IP, Block - Reported in the literature, not verified in house
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

Clone 93 can be used for blocking of CD16/CD32 interactions with the Fc domain of immunoglobulins, but is not the same clone as 2.4G2.

The 93 mAb is specific to the common epitope of CD16/CD32. Additional reported applications (for the relevant formats) include: immunoprecipitation1 and blocking of Fc-mediated reactions in functional studies2,4,23. It is useful for blocking non-specific binding of immunoglobulin to Fc receptors. For blocking of Fc receptors in flow cytometric analysis, pre-incubate the cells with purified anti-CD16/CD32 antibody (=1.0 µg per 106 cells in 100 µL volume) for 5-10 minutes on ice prior to immunostaining. For highly sensitive assays, we recommend Ultra-LEAF™ purified antibody (Cat. No. 101330) (Endotoxin <0.01 EU/µg, Azide-Free, 0.2 µm filtered).

Application References
  1. Personal communication (IP)
  2. Oliver AM, et al. 1999. Hybridoma 18:113. (Block)
  3. Brummel R and Lenert P. 2005. J. Immunol. 174:2429.
  4. Terrazas LI, et al. 2005. Int. J. Parasitol. 35:1349. (Block)
  5. Clements JL, et al. 2006. J. Immunol. 177:905.
  6. Mohamed W, et al. 2010. Infect Immun. 78:3306. PubMed
  7. Ouchi T, et al. 2011. J. Exp Med. 208:2607. PubMed
  8. Kmieciak M, et al. 2011. J. Vis. Exp. 47:2381. PubMed
  9. Yamazaki S, et al. 2012. PLoS One. 7:e51665. PubMed
  10. Li J, et al. 2012. Arthritis Rheum. 64:1098. PubMed
  11. Azuma M, et al. 2012. Oncoimmunology. 1:581. PubMed
  12. Koon HW, et al. 2013. J. Vis. Exp. 68:4208. PubMed
  13. Hegde VL, et al. 2013. J Biol Chem. 288:36810. PubMed
  14. Huang J, et al. 2013. J. Immunol Methods. 387:254. PubMed
  15. Dutow P, et al. 2014. J Infect Dis. PubMed
  16. Fan Y, et al. 2014. J Exp Med. 211:313. PubMed
  17. Huang HN, et al. 2014. Antimicrob Agents Chemother. 58:1538. PubMed
  18. Takei S, et al. 2014. Vaccine. 32:3066. PubMed
  19. Richardson ML, et al. 2014. PLoS Negl Trop Dis. 8:2825. PubMed
  20. Cekanaviciute E, et al. 2014. J Immunol. 193:139. PubMed
  21. Kimura T, et al. 2014. Int Immunol. 26:697. PubMed
  22. Everad A, et al. 2014. Nat Commun. 5:5648. PubMed
  23. Cenci E, et al. 2006. J. Leuko. Biol. 79(1):40-5. (Block)
Product Citations
  1. Sade-Feldman M,et al. 2017. Nat Commun.. 10.1038/s41467-017-01062-w. PubMed
  2. Michela Miani et al. 2018. Cell metabolism. 28(4):557-572 . PubMed
  3. Gan T, et al. 2019. Front Microbiol. 9:3174. PubMed
  4. Furuhashi K, et al. 2017. Immunology. 151:227. PubMed
  5. Fomin ME, et al. 2017. Cell Med. 0.45625. PubMed
  6. Tomida S, et al. 2019. Sci Rep. 9:10751. PubMed
  7. Filippini D, et al. 2019. Sci Rep. 9:12286. PubMed
  8. Flamar AL, et al. 2020. Immunity. 52(4):606-619.e6.. PubMed
  9. Lee J, et al. 2015. Hum Reprod. 10.1093/humrep/dev222. PubMed
  10. Bussières-Marmen S, et al. 2017. Cell Mol Immunol. 10.1038/cmi.2016.72. PubMed
  11. Chida J, et al. 2020. PLoS Pathog. 16:e1008823. PubMed
  12. Iyer S, et al. 2021. Cancer Discov. 0.725. PubMed
  13. Park E, et al. 2021. Journal of Neuroscience Research. . PubMed
  14. Gabitova-Cornell L, et al. 2020. Cancer Cell. 38(4):567-583.e11. PubMed
  15. Kosti P, et al. 2021. Cell Reports Medicine. 2(4):100227. PubMed
  16. Barkaway A, et al. 2021. Immunity. . PubMed
  17. Shah D, et al. 2021. Oncoimmunology. 10:1939601. PubMed
  18. Hutton C, et al. 2021. Cancer Cell. 39:1227. PubMed
  19. Foster A, et al. 2021. EBioMedicine. 71:103571. PubMed
  20. Kiepura A, et al. 2021. Int J Mol Sci. 22:. PubMed
  21. Rajagopalan A, et al. 2021. Cell Rep Methods. 1:. PubMed
  22. Guo H, et al. 2020. Curr Protoc Immunol. 131:e107. PubMed
  23. Van Braeckel-Budimir N, et al. 2021. J Immunother Cancer. 9:. PubMed
  24. Wang Z, et al. 2022. Proc Natl Acad Sci U S A. 119:. PubMed
  25. Xiang G, et al. 2022. Cell Death Dis. 13:451. PubMed
  26. Nederlof R, et al. 2022. Front Immunol. 13:908023. PubMed
  27. Cerrato G, et al. 2021. Cell Death Differ. 28:1733. PubMed
  28. Da Mesquita S, et al. 2021. Nature. 593:255. PubMed
  29. Liu C, et al. 2022. Nat Nanotechnol. 17:531. PubMed
  30. Jebbawi F, et al. 2021. Parasite Immunol. 43:e12834. PubMed
  31. Thomas R, et al. 2021. Immunology. 163:478. PubMed
  32. Herz J, et al. 2021. Neuron. 109:3609. PubMed
  33. Li H, et al. 2022. Cancer Cell. 40:36. PubMed
  34. Glynn RA, et al. 2022. J Immunol. 208:371. PubMed
  35. Kozuki S, et al. 2022. Genes Cells. 27:192. PubMed
  36. Bettke JA, et al. 2022. Infect Immun. 90:e0007022. PubMed
  37. Guttman O, et al. 2022. J Cell Biol. 221: . PubMed
  38. Miyao T, et al. 2022. Elife. 11: . PubMed
  39. Yin K, et al. 2022. Genes Dev. 36:533. PubMed
  40. Malhi H, et al. 2022. Cell Rep Med. 3:100658. PubMed
  41. Zhang Y, et al. 2022. Vaccines (Basel). 10: . PubMed
  42. Sugimoto S, et al. 2022. Nat Metab. 4:775. PubMed
  43. Hong Y, et al. 2022. J Leukoc Biol. 112:425. PubMed
  44. Que W, et al. 2022. Sci Adv. 8:eabo4413. PubMed
  45. Li X, et al. 2022. Cell Mol Gastroenterol Hepatol. 14:1077. PubMed
  46. Akalu YT, et al. 2022. Elife. 11: . PubMed
  47. Zhang X, et al. 2022. EBioMedicine. 84:104275. PubMed
  48. Bottermann K, et al. 2022. Basic Res Cardiol. 117:48. PubMed
  49. Hao J, et al. 2022. Cell Rep. 41:111804. PubMed
  50. McNamara NB, et al. 2023. Nature. 613:120. PubMed
  51. Miró L, et al. 2022. Cancers (Basel). 14: . PubMed
  52. Liu P, et al. 2023. Clin Immunol. 246:109212. PubMed
  53. Ullah I, et al. 2023. Cell Rep Med. 4:100893. PubMed
  54. Al-Saafeen BH, et al. 2023. Front Immunol. 13:1017780. PubMed
  55. Cousin N, et al. 2022. Cells. 12: . PubMed
  56. Peng Q, et al. 2023. EMBO Rep. 24:e56034. PubMed
  57. Tichet M, et al. 2023. Immunity. 56:162. PubMed
  58. Zhou H, et al. 2023. Front Immunol. 13:1059687. PubMed
  59. Mandour MF, et al. 2023. Front Med (Lausanne). 9:1057252. PubMed
  60. Kemna J, et al. 2023. Nat Immunol. 24:414. PubMed
  61. Novaj A, et al. 2023. Int J Mol Sci. 24: . PubMed
  62. Ishikawa T, et al. 2023. Bio Protoc. 13:e4588. PubMed
  63. Liu X, et al. 2022. Pain. 163:508. PubMed
  64. Zhang M, et al. 2022. Mol Imaging Biol. 24:280. PubMed
  65. Zhang W, et al. 2022. Dev Cell. 57:329. PubMed
  66. Kodali S, et al. 2022. J Immunol. 208:1085. PubMed
  67. Chen K, et al. 2022. Adv Sci (Weinh). 9:e2104106. PubMed
  68. Zhang H, et al. 2022. Nat Cancer. 3:808. PubMed
  69. Fang Y, et al. 2022. Sci Immunol. 7:eabp9962. PubMed
  70. Koch MS, et al. 2022. Mol Ther Oncolytics. 26:275. PubMed
  71. Harapas CR, et al. 2022. Sci Immunol. 7:eabi4611. PubMed
  72. Ding P, et al. 2022. Elife. 11:. PubMed
  73. Deák P, et al. 2022. Cell Rep. 41:111563. PubMed
  74. Zhong J, et al. 2022. J Adv Res. 41:145. PubMed
  75. Melo-Silva CR, et al. 2022. Cell Rep. 41:111676. PubMed
  76. Li Y, et al. 2023. Adv Mater. 35:e2208923. PubMed
  77. Wu Q, et al. 2023. Front Immunol. 13:1081719. PubMed
  78. Li L, et al. 2023. iScience. 26:106095. PubMed
  79. Torrente D, et al. 2023. J Neuroinflammation. 20:56. PubMed
  80. Bai X, et al. 2023. Nat Commun. 14:1247. PubMed
  81. Rocca Y, et al. 2023. Methods Mol Biol. 2618:187. PubMed
  82. Dang YZ, et al. 2023. Neoplasma. 70:123. PubMed
  83. Senatus L, et al. 2023. Commun Biol. 6:280. PubMed
  84. Kudo T, et al. 2023. iScience. 26:106342. PubMed
  85. Liu KY, et al. 2023. Environ Health Perspect. 131:37014. PubMed
  86. Zhang YN, et al. 2023. Nat Commun. 14:1985. PubMed
  87. Iguchi A, et al. 2023. iScience. 26:106375. PubMed
  88. Feng Y, et al. 2023. J Transl Med. 21:290. PubMed
  89. Ji Y, et al. 2023. Nat Cell Biol. 25:726. PubMed
  90. Liu JC, et al. 2023. Int J Mol Sci. 24:. PubMed
  91. Petenkova A, et al. 2023. Nat Commun. 14:2761. PubMed
  92. Xu J, et al. 2023. Discov Oncol. 14:68. PubMed
  93. An R, et al. 2022. Cell Insight. 1:100047. PubMed
  94. Wang K, et al. 2023. Nat Commun. 14:2950. PubMed
  95. Amirova KM, et al. 2023. Int J Mol Sci. 24:. PubMed
  96. Li M, et al. 2023. BMC Cancer. 23:497. PubMed
  97. Mawambo G, et al. 2023. J Neuroinflammation. 20:145. PubMed
  98. Akasaka H, et al. 2023. JCI Insight. 8:. PubMed
  99. Kitagawa S, et al. 2022. NPJ Vaccines. 7:115. PubMed
  100. Golden GJ, et al. 2021. MBio. 12:e0118121. PubMed
  101. Yu Y, et al. 2022. iScience. 25:105004. PubMed
  102. Huang Y, et al. 2021. Nat Immunol. 22:586. PubMed
  103. MacLean M, et al. 2022. Commun Biol. 5:177. PubMed
  104. Effern M, et al. 2022. STAR Protoc. 3:101038. PubMed
  105. Rødahl I, et al. 2021. STAR Protoc. 2:100842. PubMed
  106. Correa S, et al. 2020. ACS Nano. 14:2224. PubMed
  107. Wong Fok Lung T, et al. 2020. Nat Microbiol. 141:5. PubMed
  108. Qian Y, et al. 2021. Cell Reports. 36(8):109602. PubMed
  109. Benitez AA, et al. 2020. Commun Biol. 0.371527778. PubMed
  110. Castoldi Â, et al. 2020. Nat Commun. 3.310416667. PubMed
  111. Mevel R, et al. 2020. eLife. 9:00. PubMed
  112. Fan Y, et al. 2014. J Exp Med. 211:313. PubMed
  113. Berry CT, et al. 2020. Cell Reports. 31(2):107474.. PubMed
  114. Rendeiro AF, et al. 2020. Nat Commun. 11:577. PubMed
  115. Biljes D, et al. 2017. EXCLI J. 0.86875. PubMed
  116. Zhang R, et al. 2019. Cell Rep. 28:2647. PubMed
  117. McGill BE et al. 2018. The Journal of Neuroscience. 38(1):200-219 . PubMed
  118. Zou B, et al. 2017. PLoS Pathogens. 13(6):e1006436. PubMed
  119. Tan H,et al. 2017. Mucosal Immunol. . 10.1038/mi.2017.89. PubMed
  120. Clarke F,et al. 2017. PLoS One. 10.1371/journal.pone.0186625. PubMed
  121. Postat J et al. 2018. Immunity. 49(4):654-665 . PubMed
  122. Minutti CM, et al. 2019. Immunity. 50:645. PubMed
  123. Farsakoglu Y et al. 2019. Cell reports. 26(9):2307-2315 . PubMed
  124. Takeda Y, et al. 2018. Innate Immun. 24:323. PubMed
  125. Goel S, et al. 2017. Nature. 548:471. PubMed
  126. Matsui S, et al. 2018. Am J Pathol. 188:2059. PubMed
  127. Bhatia D, et al. 2019. JCI Insight. 4:e132826. PubMed
  128. Noh JR, et al. 2018. Sci Rep. 8:15222. PubMed
  129. Flores M, et al. 2008. FASEB J. 3.459027778. PubMed
  130. Tong J, et al. 2011. J Immunol. 186:3686. PubMed
  131. Weng L, et al. 2016. Sci Rep. 6:38632. PubMed
  132. Browning D, et al. 2017. Gene Ther. 10.1038/gt.2016.88. PubMed
  133. Morris MG, et al. 2020. Comp Med. 70:336. PubMed
  134. Sano T, et al. 2021. Cell Reports. 36:109608. PubMed
  135. Martos-Rus C, et al. 2021. Sci Rep. 11:2974. PubMed
  136. Liu P, et al. 2021. Front Med (Lausanne). 8:625130. PubMed
  137. Song J, et al. 2021. J Am Heart Assoc. 10:e017329. PubMed
  138. Jiang W, et al. 2021. Oncol Lett. 22:625. PubMed
  139. Khamissi FZ, et al. 2022. Sci Adv. 8:eabm5900. PubMed
  140. Chen L, et al. 2022. Mol Ther Oncolytics. 24:522. PubMed
  141. Almeida AS, et al. 2021. Bio Protoc. 11:e4012. PubMed
  142. Feng J, et al. 2021. iScience. 24:103004. PubMed
  143. Wu L, et al. 2022. Front Immunol. 13:860761. PubMed
  144. Bauer KM, et al. 2022. JCI Insight. 7:. PubMed
  145. Diao L, et al. 2022. iScience. 25:105511. PubMed
  146. Zhang Y, et al. 2022. Cancers (Basel). 14:. PubMed
  147. Mirshahi F, et al. 2022. Cell Rep. 38:110454. PubMed
  148. Sun SJ, et al. 2022. Commun Biol. 5:867. PubMed
  149. Chen X, et al. 2021. Cell Death Differ. 28:1237. PubMed
  150. Roberto Raúl SG, et al. 2022. Breast Cancer (Auckl). 16:11782234211065154. PubMed
  151. Matthias J, et al. 2020. J Clin Invest. 130:4587. PubMed
  152. Menzel L, et al. 2021. Cell Rep. 37:109878. PubMed
  153. Liang F, et al. 2021. Front Immunol. 12:658715. PubMed
  154. Jenull S, et al. 2021. Cell Reports. 36(3):109406. PubMed
  155. Clark AL, et al. 2021. Diabetes Obesity and Metabolism. :. PubMed
  156. Stahnke S, et al. 2021. Current Biology. 31(10):2051-2064.e8. PubMed
  157. Yang SB, et al. 2021. Cancers (Basel). 13:00. PubMed
  158. Elisabeth Schrumpf, Xiaojun Jiang 2017. Physiol Rep. 10.14814/phy2.13117. PubMed
  159. Koon H, et al. 2012. J Vis Exp. 68: 4208. PubMed
  160. Azuma M, et al. 2012. Oncoimmunology. 1:581. PubMed
  161. Yamazaki S, et al. 2012. PLoS One. 7:e51665. PubMed
  162. Yang W, et al. 2020. Nat Commun. 3.553472222. PubMed
  163. Hays C, et al. 2020. eLife. 8:e48772.. PubMed
  164. Li Y, et al. 2020. Cell Rep. 30:1753. PubMed
  165. Gawden‐Bone CM et al. 2018. Immunity. 49(3):427-437 . PubMed
  166. Tyagi AM et al. 2018. Immunity. 49(6):1116-1131 . PubMed
  167. Oyarce C, et al. 2018. Front Immunol. 8:1794. PubMed
  168. Nakagawa S et al. 2017. Cell host & microbe. 22(5):667-677 . PubMed
  169. Mann M, et al. 2018. Cell Rep. 25:2992. PubMed
  170. Fiala GJ, et al. 2019. J Immunol. 203:569. PubMed
  171. Dave K et al. 2017. eLife. 6 pii: e23382. PubMed
  172. Kitashima DY, et al. 2018. EBioMedicine. 27:293. PubMed
  173. Li Y, et al. 2018. J Immunol. 201:2910. PubMed
  174. Carlson P, et al. 2019. Nat Cell Biol. 21:238. PubMed
  175. Wu J, et al. 2020. Sci Adv. 6:eaba3458. PubMed
  176. Guan H, et al. 2012. PLoS One. 7:e35650. PubMed
  177. Hazama D, et al. 2020. Cell Chemical Biology. 27(9):1181-1191.e7. PubMed
  178. Shemer A, et al. 2020. Immunity. 53(5):1033-1049.e7. PubMed
  179. Schiller M, et al. 2021. Immunity. 54(5):1022-1036.e8. PubMed
  180. Okuniewska M, et al. 2021. Cell Reports. 36(2):109368. PubMed
  181. Zhao B, et al. 2021. Cell Reports. 36(3):109401. PubMed
  182. Webster HC, et al. 2020. J Immunol Methods. 112702:477. PubMed
  183. Godbersen-Palmer C, et al. 2020. J Immunol. 204:2973. PubMed
  184. Yang C, et al. 2020. J Control Release. 326:324. PubMed
  185. Liu D, et al. 2021. JCI Insight. 6:. PubMed
  186. Armaka M, et al. 2022. Genome Med. 14:78. PubMed
  187. Hoffman D, et al. 2021. Immunity. 54:2712. PubMed
  188. Shen H, et al. 2022. Nat Commun. 13:6030. PubMed
  189. Wang Y, et al. 2022. Front Immunol. 13:767630. PubMed
  190. Ma J, et al. 2021. Aging (Albany NY). 13:7211. PubMed
  191. Yu M, et al. 2021. J Clin Invest. 131:. PubMed
  192. Cousin N, et al. 2021. Cancer Res. 81:4133. PubMed
  193. Haugh KA, et al. 2021. eLife. 0.416666666666667. PubMed
  194. Tal MC, et al. 2020. MBio. 11:00. PubMed
  195. Zhang X, et al. 2020. J Immunol. 205:1743. PubMed
  196. Kovacs L, et al. 2020. PLoS One. 15:e0240455. PubMed
  197. Vackova J, et al. 2020. Int J Mol Sci. 21:00. PubMed
  198. Terrazas LI, et al. 2005. Int J Parasit. 35:1349. PubMed
  199. Bhattacherjee A, et al. 2019. Commun Biol. 2:450. PubMed
  200. Lieschke S, et al. 2019. Cells. 0.420833333. PubMed
  201. Sereni L, et al. 2018. J Allergy Clin Immunol. 142:1272. PubMed
  202. Fransen F, et al. 2017. Front Immunol. 1.295138889. PubMed
  203. Nakamura‐Ishizu A et al. 2018. Cell reports. 25(7):1772-1785 . PubMed
  204. Wlodarska M et al. 2017. Cell host & microbe. 22(1):25-37 . PubMed
  205. Wang L, et al. 2017. Front Immunol.. 10.3389/fimmu.2017.01754. PubMed
  206. Fiaturi N, et al. 2018. J Cell Commun Signal. 314:L127. PubMed
  207. Barajas‐Mora EM et al. 2018. Molecular cell. 73(1):48-60 . PubMed
  208. Fujita Y et al. 2018. Cell reports. 24(12):3296-3311 . PubMed
  209. Uchil PD et al. 2018. Cell host & microbe. 25(1):87-100 . PubMed
  210. Koliaraki V et al. 2019. Cell reports. 26(3):536-545 . PubMed
  211. Finn J et al. 2019. Cell reports. 26(11):2942-2954 . PubMed
  212. Barger SR, et al. 2019. Nat Commun. 10:1249. PubMed
  213. Shimokawa C et al. 2017. Immunity. 46(5):863-874 . PubMed
  214. Caronni N, et al. 2018. Cancer Res. 78:1685. PubMed
  215. Weiner AI, et al. 2019. NPJ Regen Med. 4:17. PubMed
  216. Russell SL, et al. 2019. Cell Rep. 29:3564. PubMed
  217. Khaw YM, et al. 2020. J Neuroinflammation. 17:49. PubMed
  218. Chen C, et al. 2019. Cell Rep. 29:4200. PubMed
  219. Damle SR, et al. 2018. Allergy. 73:125. PubMed
  220. Cheng XS, et al. 2020. J Cell Mol Med. 24:8391. PubMed
  221. Kohn M, et al. 2021. Front Immunol. 580594:12. PubMed
  222. Liang Z, et al. 2020. Pain. 161:2089. PubMed
  223. Gui J, et al. 2020. Nat Cancer. 1:603. PubMed
  224. Hore ZL, et al. 2021. Wellcome Open Res. 6:68. PubMed
  225. Sheller-Miller S, et al. 2021. Sci Adv. 7:. PubMed
  226. Mao W, et al. 2021. Int J Mol Sci. 22:. PubMed
  227. Dang Y, et al. 2022. Cancer Cell Int. 22:88. PubMed
  228. Almeida AS, et al. 2021. Bio Protoc. 11:e4012. PubMed
  229. Cong M, et al. 2021. Methods Mol Biol. 2388:59. PubMed
  230. Menzel L, et al. 2022. STAR Protoc. 3:101267. PubMed
  231. Escudero-Lara A, et al. 2022. Front Behav Neurosci. 16:946975. PubMed
  232. Lopez DA, et al. 2022. Cell Rep. 41:111677. PubMed
  233. Ruf B, et al. 2021. Cancer Immunol Res. 9:1024. PubMed
  234. Muñoz NM, et al. 2022. Sci Rep. 12:14449. PubMed
  235. Hu G, et al. 2022. Cell Death Dis. 13:640. PubMed
  236. Sun Y, et al. 2022. Nat Commun. 13:3916. PubMed
  237. Korangath P, et al. 2020. Bio Protoc. 10:e3822. PubMed
  238. Flommersfeld S, et al. 2021. Immunity. :. PubMed
  239. Wong HS, et al. 2021. Cell. . PubMed
  240. Kusuyama J, et al. 2021. Cell Metabolism. 33(5):939-956.e8. PubMed
  241. Alshetaiwi H, et al. 2020. Sci Immunol. 5:00. PubMed
  242. Gereke M, et al. 2012. J Vis Exp. 70: 4322. PubMed
  243. MacConmara M, et al. 2011. J Leukoc Biol. 89:137. PubMed
  244. Cassidy LD, et al. 2018. Autophagy. 1.455555556. PubMed
  245. Fransen F, et al. 2017. Front Immunol. 8:154. PubMed
  246. Yang SH, et al. 2017. Front Immunol. 8:1192. PubMed
  247. Lagares D, et al. 2017. Sci Transl Med. 9:eaal3765. PubMed
  248. McLaughlin PA et al. 2019. PLoS Pathog. 15(7):e1007847 . PubMed
  249. Mrdjen D et al. 2018. Immunity. 48(2):380-395 . PubMed
  250. Go MJ, et al. 2018. Mol Med Rep. 13:e0194423. PubMed
  251. McGrath-Morrow S, et al. 2017. Cytokine. 10.1016/j.cyto.2017.06.002. PubMed
  252. Csóka B, et al. 2018. JCI Insight. 38:200. PubMed
  253. Proto JD et al. 2018. Immunity. 49(4):666-677 . PubMed
  254. Rashidi M, et al. 2019. J Immunol. 203:736. PubMed
  255. Deng M, et al. 2020. Nat Commun. 11:2193. PubMed
  256. Hashimoto M, et al. 2019. FASEB J. 33:8069. PubMed
  257. Everard A, et al. 2014. Nat Commun. 5:5648. PubMed
  258. Francis M, et al. 2017. Toxicol Sci. 155(1):182-195. PubMed
  259. Hu J, et al. 2020. Theranostics. 7.154166667. PubMed
  260. Baasch S, et al. 2021. Cell. . PubMed
  261. Sutherland TE, et al. 2021. Frontiers in Immunology. 12:715209. PubMed
  262. Zheng J, et al. 2020. bioRxiv. . PubMed
  263. Imani J, et al. 2021. JCI Insight. 6:. PubMed
  264. Dang Y, et al. 2021. J Cancer. 12:7158. PubMed
  265. Du Y, et al. 2022. Nat Commun. 13:231. PubMed
  266. Pishesha N, et al. 2021. Proc Natl Acad Sci U S A. 118:. PubMed
  267. Chin AL, et al. 2021. Nat Commun. 12:5138. PubMed
  268. Hong CH, et al. 2021. Cell Mol Gastroenterol Hepatol. 13:925. PubMed
  269. Lin C, et al. 2022. Nat Commun. 13:6869. PubMed
  270. De Santi C, et al. 2022. Mol Ther Nucleic Acids. 29:643. PubMed
  271. Pereira M, et al. 2022. Cell Rep. 40:111225. PubMed
  272. Kim S, et al. 2022. Redox Biol. 54:102347. PubMed
  273. Chen Y, et al. 2022. Front Immunol. 13:835690. PubMed
  274. Zeng Q, et al. 2022. Front Immunol. 13:740805. PubMed
  275. Welte T, et al. 2021. iScience. 24:103349. PubMed
  276. Baier FA, et al. 2021. Cell Mol Gastroenterol Hepatol. 12:745. PubMed
  277. Li Y, et al. 2021. Sci Transl Med. 13:. PubMed
  278. Dobosz E, et al. 2021. Dis Model Mech. :14. PubMed
  279. Hubbard JJ, et al. 2020. J Exp Med. :217. PubMed
  280. Xu S, et al. 2021. Immunity. . PubMed
  281. Tacconi C, et al. 2021. Cell Reports. 35(2):108993. PubMed
  282. Dieterich LC, et al. 2020. Angiogenesis. 1.24375. PubMed
  283. Duvigneau S, et al. 2016. Sci Rep. 6:37045. PubMed
  284. Siggs O, et al. 2015. Proc Natl Acad Sci U S A. 112: E5706 - E5714. PubMed
  285. Moon H, et al. 2020. Nat Commun. 4.270138889. PubMed
  286. Kulkarni U, et al. 2019. Mucosal Immunol. 12:545. PubMed
  287. Tsubaki T, et al. 2018. Oncotarget. 9:11209. PubMed
  288. Qi S et al. 2016. eLife. 5 pii: e14756. PubMed
  289. Roy K, et al. 2019. Immunity. 50:616. PubMed
  290. Matsumoto K, et al. 2017. PLoS One. 12(6):e0175406. PubMed
  291. Sauma D, et al. 2017. Immunol Res. 10.1007/s12026-017-8936-9. PubMed
  292. Gil-Pulido J, et al. 2017. PLoS One.. 10.1371/journal.pone.0181947. PubMed
  293. Yu L, et al. 2019. Elife. 8:e46677. PubMed
  294. Chen JC, et al. 2018. Front Immunol. 0.665277778. PubMed
  295. Peng L, et al. 2019. Mol Med Rep. 19:2876. PubMed
  296. Shin J, et al. 2018. Diabetes. 67:1068. PubMed
  297. Dutow P, et al. 2014. J Infect Dis. 209:1269. PubMed
  298. Huang H, et al. 2014. Antimicrob Agents Chemother. 58:1538. PubMed
  299. Lehmann GL, et al. 2020. J Exp Med. 217:00:00. PubMed
  300. Zhao L, et al. 2020. EBioMedicine. 60:103020. PubMed
  301. Riedelberger M, et al. 2020. Bio Protoc. e3552:10. PubMed
  302. Yan W, et al. 2021. Front Med (Lausanne). 8:752223. PubMed
  303. Sun C, et al. 2022. J Adv Res. 35:71. PubMed
  304. Lüönd F, et al. 2022. STAR Protoc. 3:101438. PubMed
  305. Germundson DL, et al. 2022. Front Allergy. 3:870513. PubMed
  306. Sundararaj K, et al. 2021. Immunology. 162:418. PubMed
  307. Jeong M, et al. 2022. JCI Insight. 7:. PubMed
  308. Chu A, et al. 2021. J Reprod Immunol. 145:103309. PubMed
  309. Frost JN, et al. 2021. Med (N Y). 2:164. PubMed
  310. Moon S, et al. 2021. J Exp Med. 218:. PubMed
  311. Hu CF, et al. 2021. Front Immunol. 12:638381. PubMed
  312. Zheng J, et al. 2020. Nature. . PubMed
  313. Unudurthi SD, et al. 2020. Life Sci. 117440:247. PubMed
  314. Yamakawa D, et al. 2021. Cell Reports. 34(10):108817. PubMed
  315. Troutman TD, et al. 2021. STAR Protocols. 2(1):100363. PubMed
  316. Li X, et al. 2020. Nat Commun. 4.877777778. PubMed
  317. Siggs O, et al. 2016. Proc Natl Acad Sci U S A. 113: 3706 - 3715. PubMed
  318. Seki T, et al. 2015. J Biochem. 158: 485 - 495. PubMed
  319. Cekanaviciute E, et al. 2014. J Immunol. 193:139. PubMed
  320. Hegde V, et al. 2013. J Biol Chem. 288:36810. PubMed
  321. Kyburz A, et al. 2019. J Allergy Clin Immunol. 143:1496. PubMed
  322. Liu C et al. 2019. Immunity. 51(2):381-397 . PubMed
  323. Enomoto D, et al. 2017. PLoS One.. 10.1371/journal.pone.0183584. PubMed
  324. Wang Z et al. 2018. Immunity. 49(1):80-92 . PubMed
  325. Zeng J, et al. 2018. J Immunol. 200:3407. PubMed
  326. Hsu BE et al. 2019. Cell Rep. 27(13):3902-3915 . PubMed
  327. Di Mitri D, et al. 2019. Cell Rep. 28:2156. PubMed
  328. Rebecca S Dickinson et al. 2017. Wellcome open research. 0.155555556 . PubMed
  329. Li B, et al. 2019. Oncol Rep. 41:608. PubMed
  330. Kretschmer L, et al. 2020. Nat Commun. 0.536805556. PubMed
  331. Fujimoto N, et al. 2020. PLoS Biol. 18:e3000704. PubMed
  332. Akk A, et al. 2019. Mol Immunol. 114:629. PubMed
  333. Kmieciak M, et al. 2011. J Vis Exp. 47: 2381. PubMed
  334. Huang BR, et al. 2020. Int J Mol Sci. 21:00. PubMed
  335. Lindborg JA, et al. 2021. Cell Reports. 34(9):108777. PubMed
  336. Ahn D, et al. 2021. Cell Reports. 35(9):109196. PubMed
  337. Tuong ZK, et al. 2021. iScience. 24:103326. PubMed
  338. Yu H, et al. 2021. Front Oncol. 11:736882. PubMed
  339. Shiozawa S, et al. 2022. iScience. 25:103537. PubMed
  340. Blanchard L, et al. 2022. STAR Protoc. 3:101444. PubMed
  341. Babagana M, et al. 2021. Aging (Albany NY). 13:19207. PubMed
  342. Han Y, et al. 2022. Int J Biol Sci. 18:5653. PubMed
  343. Matsuda T, et al. 2022. iScience. 25:105324. PubMed
  344. Takahashi F, et al. 2022. iScience. 25:104278. PubMed
  345. Saveljeva S, et al. 2022. Cell Metab. 34:106. PubMed
  346. Zhang YN, et al. 2021. Sci Adv. 7:eabj3107. PubMed
  347. Shibuya M, et al. 2021. iScience. 24:103131. PubMed
  348. Ben-Yehuda H, et al. 2021. Mol Neurodegener. 16:39. PubMed
  349. Mohammadi MR, et al. 2021. Commun Biol. 4:685. PubMed
  350. Vilcaes AA, et al. 2020. Int J Mol Sci. :21. PubMed
  351. Zhao L, et al. 2021. STAR Protocols. 2:100732. PubMed
  352. Desai P, et al. 2021. Cell. 184(5):1214-1231.e16. PubMed
  353. Lehmann ML, et al. 2020. Brain Behav Immun. 88:735. PubMed
  354. Xu G, et al. 2020. Cell Rep. 32:108170. PubMed
  355. Takei S, et al. 2014. Vaccine. 32:3066. PubMed
  356. Constantinides M, et al. 2011. J Immunol. 187:309. PubMed
  357. Lenert R 2005. J Immunol. 174:2429. PubMed
  358. Ramachandran P, et al. 2019. Nature. 575:512. PubMed
  359. Spranger S, et al. 2017. Cancer Cell. 31:711. PubMed
  360. Burgener SS, et al. 2019. Cell Rep. 27:3646. PubMed
  361. Sanchez M et al. 2017. Cell host & microbe. 22(4):543-551 . PubMed
  362. Shibamoto M, et al. 2019. Int Heart J. 60:944. PubMed
  363. Okuma A, et al. 2017. Nat Commun.. 10.1038/s41467-017-02281-x. PubMed
  364. Kang YH, et al. 2019. Nat Commun. 10:912. PubMed
  365. Tellechea M, et al. 2018. J Immunol. 200:305. PubMed
  366. Oliveira AC et al. 2017. eLife. 6 pii: e30883. PubMed
  367. Lyle C, et al. 2019. Sci Rep. 9:20257. PubMed
  368. Roussey JA, et al. 2017. J Immunol. 199:3535. PubMed
  369. Mandour MF, et al. 2020. Infect Agent Cancer. 15:30. PubMed
  370. Kolter J, et al. 2020. Immunity. 50(6):1482-1497. PubMed
  371. Nakav S, et al. 2009. Nephrol Dial Transplant. 25:931. PubMed
  372. Miranda-Hernandez S, et al. 2011. J Immunol. 187:791. PubMed
  373. Miura N, et al. 2017. Mol Ther. 10.1016/j.ymthe.2017.01.020. PubMed
  374. Liu P, et al. 2020. Mol Cell. 748:77. PubMed
  375. Zhang Y, et al. 2020. Cancer Res. 80:3345. PubMed
  376. Bi J, et al. 2022. Front Microbiol. 13:927122. PubMed
  377. Zhang MH, et al. 2020. Front Immunol. 11:560. PubMed
  378. Tomimatsu M, et al. 2022. Sci Rep. 12:16656. PubMed
  379. López-Sanz C, et al. 2022. STAR Protoc. 3:101755. PubMed
  380. Alshetaiwi H, et al. 2020. Methods Mol Biol. 2236:177. PubMed
  381. Ma L, et al. 2022. Sci Adv. 8:eabm3470. PubMed
  382. Leary N, et al. 2022. J Extracell Vesicles. 11:e12197. PubMed
  383. Lee SA, et al. 2021. Cells. 10:. PubMed
  384. Chida K, et al. 2021. Biol Pharm Bull. 44:1551. PubMed
  385. Saxena M, et al. 2020. Cancer Res. 80:3631. PubMed
  386. Chen C, et al. 2020. Cell Rep. 2136:30. PubMed
  387. Ouchi T, et al. 2011. J Exp Med. 208:2607. PubMed
  388. Baumann D, et al. 2020. Nat Commun. 1.969444444. PubMed
  389. Forster R, et al. 2019. FASEB J. 33:11210. PubMed
  390. Heinen A, et al. 2019. Mol Ther. 27:46:00. PubMed
  391. Simmons S et al. 2019. Elife. 8 pii: e41239. PubMed
  392. William M, et al. 2018. J Immunol. 200:4102. PubMed
  393. Contreras NA, et al. 2019. PLoS Pathog. 15:e1007890. PubMed
  394. Miura Y et al. 2018. eLife. 7 pii: e36572. PubMed
  395. Zhao N, et al. 2018. J Clin Invest. 26:84. PubMed
  396. Gaya M et al. 2018. Cell. 172(3):517-533 . PubMed
  397. Freeman SA et al. 2018. Cell. 172(1-2):305-317 . PubMed
  398. Glodde N et al. 2017. Immunity. 47(4):789-802 . PubMed
  399. Knox T, et al. 2019. Sci Rep. 9:6136. PubMed
  400. Rojo R, et al. 2019. Nat Commun. 10:3215. PubMed
  401. Schaftenaar FH, et al. 2019. Sci Rep. 9:17391. PubMed
  402. Deng M, et al. 2019. J Exp Med. 216:2838. PubMed
  403. Hong JP, et al. 2020. Cell Reports Medicine. 1(3):100035. PubMed
  404. Clements J, et al. 2006. J Immunol. 177:905. PubMed
  405. Kimura T, et al. 2014. Int Immunol. 26:697. PubMed
  406. Howe C, et al. 2016. Sci Rep. 6:28699. PubMed
  407. Blaszczak AM, et al. 2020. Immunometabolism. 2:00. PubMed
  408. Senatus L, et al. 2020. JCI Insight. 5:00. PubMed
  409. Matsumoto M, et al. 2021. Cell Host Microbe. 29(6):930-940.e4. PubMed
  410. Jin HS, et al. 2020. Cancer Immunol Res. 8:912. PubMed
  411. Sakurai Y, et al. 2021. Pharmaceutics. 13:. PubMed
  412. Banskota S, et al. 2021. Inflamm Bowel Dis. 27:914. PubMed
  413. Magaletta ME, et al. 2022. Nat Commun. 13:457. PubMed
  414. Tzeng TT, et al. 2022. NPJ Vaccines. 7:60. PubMed
  415. Chryplewicz A, et al. 2022. Cancer Cell. 40:1111. PubMed
  416. Sheng D, et al. 2022. J Immunother Cancer. 10:. PubMed
  417. Dong H, et al. 2022. Nat Metab. 4:90. PubMed
  418. Chetty A, et al. 2021. Cell Host Microbe. 29:579. PubMed
  419. Qiu Z, et al. 2020. Cancer Genet. 245:6. PubMed
  420. Kohn M, et al. 2021. Front Immunol. 626627:12. PubMed
  421. Bonavita E, et al. 2020. Immunity. 1215:53. PubMed
  422. Luo X, et al. 2021. Neuron. 109:2691. PubMed
  423. McDonald MM, et al. 2021. Cell. 184(5):1330-1347.e13. PubMed
  424. Alam MM, et al. 2021. eneuro. 8(1):. PubMed
  425. Sitapara RA, et al. 2020. Mol Med. 26:63. PubMed
  426. Kim K, et al. 2015. Infect Immun . 83:1150. PubMed
  427. Penzo M, et al. 2010. J Immunol. 184:4497. PubMed
  428. Mehrpouya-Bahrami P, et al. 2019. J Biol Chem. 294:7669. PubMed
  429. Burton OT, et al. 2018. Clin Exp Allergy. 48:288. PubMed
  430. Blaszczak AM, et al. 2019. J Immunol. 202:2451. PubMed
  431. Sivaram N, et al. 2019. J Clin Invest. 130. PubMed
  432. Litwinoff EMS, et al. 2017. Obes Res Clin Pract. 12:174. PubMed
  433. Burl RB et al. 2018. Cell metabolism. 28(2):300-309 . PubMed
  434. Li Z et al. 2018. Immunity. 49(4):640-653 . PubMed
  435. Lyons DO, et al. 2018. PLoS One. 13:e0207704. PubMed
  436. Li A, et al. 2018. Cancer Lett. 431:54. PubMed
  437. Steinmann S, et al. 2020. Sci Rep. 1.160416667. PubMed
  438. Li J, et al. 2012. Arthritis Rheum. 64:1098. PubMed
  439. Melero I, et al. 2015. Cancer Res. 75:497. PubMed
  440. Hegde V, et al. 2015. J Immunol. 194:5211. PubMed
  441. Katsuyama T, et al. 2021. Cell Reports. 36(1):109339. PubMed
  442. Goldberg EL, et al. 2021. Cell Metabolism. :. PubMed
  443. Phadke MS, et al. 2021. Cancer Immunol Res. 9:554. PubMed
  444. Sibler E, et al. 2021. Cells. 10:. PubMed
  445. Qin J, et al. 2020. Cancer Immunol Res. 8:1426. PubMed
  446. Guo Y, et al. 2021. Nat Immunol. 22:746. PubMed
  447. Zhang M, et al. 2022. iScience. 25:104490. PubMed
  448. Kastenschmidt JM, et al. 2021. Cell Rep. 35:108997. PubMed
  449. Sibler E, et al. 2022. Cancers (Basel). 14:. PubMed
  450. Effern M, et al. 2020. Immunity. 53(3):564-580.e9. PubMed
  451. Liu Q, et al. 2016. Cell Death Dis. 1.93125. PubMed
  452. Richardson M, et al. 2014. PLoS Negl Trop Dis. 8:2825. PubMed
  453. Huanga J, et al. 2013. J Immunol Methods. 387:254. PubMed
  454. Malinczak CA, et al. 2019. J Immunol. 10.4049/jimmunol.1900741. PubMed
  455. Wang X, et al. 2018. Front Immunol. 9:2615. PubMed
  456. Kabir AU, et al. 2018. JCI Insight. 3. PubMed
  457. Buschor S, et al. 2017. PLoS Pathogens. 13(6):e1006476. PubMed
RRID
AB_312800 (BioLegend Cat. No. 101301)
AB_312800 (BioLegend Cat. No. 101302)

Antigen Details

Structure
Ig superfamily, 40-60 kD
Distribution

B cells, monocyte/macrophages, NK cells, neutrophils, mast cells, dendritic cells

Function
Low affinity receptors for IgG
Ligand/Receptor
IgG
Cell Type
B cells, Dendritic cells, Macrophages, Mast cells, Monocytes, Neutrophils, NK cells
Biology Area
Immunology, Innate Immunity
Molecular Family
CD Molecules, Fc Receptors
Antigen References

1. Barclay AN, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Unkeless JC. 1989. J. Clin. Invest. 83:355.
3. Qiu WQ, et al. 1990. Science 248:732.

Gene ID
14130 View all products for this Gene ID 14131 View all products for this Gene ID
UniProt
View information about CD16/32 on UniProt.org
Go To Top Version: 2    Revision Date: 01.23.2015

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

BioLegend, the BioLegend logo, and all other trademarks are property of BioLegend, Inc. or their respective owners, and all rights are reserved.

 

8999 BioLegend Way, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

ProductsHere
Login / Register
Remember me
Forgot your password? Reset password?
Create an Account