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Purified anti-mouse CD38 Antibody

Pricing & Availability
Clone
S21016F (See other available formats)
Regulatory Status
RUO
Other Names
T10
Isotype
Rat IgG2b, κ
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Product Citations
publications
a-S21016F_Purified_CD38_Antibody-032423
C57BL/6 mouse splenocytes were stained with purified anti-mouse CD38 (clone S21016F) or purified rat IgG2b, κ isotype control followed by goat-anti-rat IgG PE. Cells were costained with anti-mouse B220 APC.
  • a-S21016F_Purified_CD38_Antibody-032423
    C57BL/6 mouse splenocytes were stained with purified anti-mouse CD38 (clone S21016F) or purified rat IgG2b, κ isotype control followed by goat-anti-rat IgG PE. Cells were costained with anti-mouse B220 APC.
  • b-S21016F_Purified_CD38_Antibody_2_121324
    C57BL/6 mouse frozen spleen section was fixed with 4% paraformaldehyde (PFA) for ten minutes at room temperature and blocked with 5% FBS for 30 minutes at room temperature. Then, the section was stained with 10 µg/mL of anti-mouse CD38 (clone S21016F) purified overnight at 4°C, followed by 2.5 µg/mL of anti-rat IgG (clone Poly4054) Alexa Fluor® 594 (red) and anti-mouse CD3ε (clone 500A2) Alexa Fluor® 647 (green) for two hours at room temperature. Nuclei were counterstained with DAPI (blue). The image was captured by 10X objective.
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165602 100 µg 88€
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Description

CD38, also known as T10, is a 45 kD type II transmembrane glycoprotein. It is an ADP-ribosyl hydrolase expressed at variable levels on hematopoietic cells and in some non-hematopoietic tissues (such as brain, muscle, and kidney). By functioning as both a cyclase and a hydrolase, CD38 mediates lymphocyte activation, adhesion, and the metabolism of cADPR and NAADP. CD31 is thought to be a ligand of CD38.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Mouse CD38 transfected cells
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Concentration
0.5 mg/mL
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested
IHC-F - Verified
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.125 µg per million cells in 100 µL volume. For immunohistochemistry on frozen tissue sections, a concentration range of 5.0 - 10.0 µg/mL is suggested. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

Clone S21016F can completely block the binding of clone “90” on target cells.

RRID
AB_2941443 (BioLegend Cat. No. 165602)

Antigen Details

Structure
ADP-ribosyl hydrolase, 42 kD
Distribution

B cells, NK cells, T cell subset, brain, muscle, kidney

Function
Regulation of cellular activation/proliferation, adhesion, metabolism of cADPR and NAADP
Ligand/Receptor
CD31, hyaluronic acid
Cell Type
B cells, Lymphocytes, NK cells, T cells
Biology Area
Cell Biology, Costimulatory Molecules, Immuno-Oncology, Immunology
Molecular Family
CD Molecules
Antigen References
  1. Barclay AN, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
  2. Shubinsky G, et al. 1997. Immunity. 7:315-24.
  3. Cesano A, et al. 1998. J Immunol. 160:1106-15.
  4. Cockayne DA, et al. 1998. Blood. 92:1324-33.
Gene ID
12494 View all products for this Gene ID
UniProt
View information about CD38 on UniProt.org

Related FAQs

There are no FAQs for this product.
Go To Top Version: 2    Revision Date: 12.13.2024

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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