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FITC anti-mouse CD45 Antibody

Pricing & Availability
Clone
30-F11 (See other available formats)
Regulatory Status
RUO
Other Names
T200, Ly-5, LCA
Isotype
Rat IgG2b, κ
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Product Citations
publications
30-f11
C57BL/6 splenocytes stained with 30-F11 FITC
  • 30-f11
    C57BL/6 splenocytes stained with 30-F11 FITC
Compare all formats See FITC spectral data
Cat # Size Price Quantity Check Availability Save
103107 50 µg 29€
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103108 500 µg 84€
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Description

CD45 is a 180-240 kD glycoprotein also known as the leukocyte common antigen (LCA), T200, or Ly-5. It is a member of the protein tyrosine phosphatase (PTP) family, expressed on all hematopoietic cells except mature erythrocytes and platelets. There are different isoforms of CD45 that arise from variable splicing of exons 4, 5, and 6, which encode A, B, and C determinants, respectively. CD45 plays a key role in TCR and BCR signal transduction. These isoforms are very specific to the activation and maturation state of the cell as well as cell type. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4, TCR, CD22, and Thy-1.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Mouse thymus or spleen
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per 106 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Application Notes

Clone 30-F11 reacts with all isoforms and both CD45.1 and CD45.2 alloantigens of CD45.

Additional reported applications (for relevant formats) include: immunoprecipitation3, complement-dependent cytotoxicity1,5, immunohistochemistry (acetone-fixed frozen sections, zinc-fixed paraffin-embedded sections and formalin-fixed paraffin-embedded sections)4,6, Western blotting7, and spatial biology (IBEX)10,11. The Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 103163 and 103164).

Application References
  1. Podd BS, et al. 2006. J. Immunol. 176:6532. (FC, CMCD) PubMed
  2. Haynes NM, et al. 2007. J. Immunol. 179:5099. (FC)
  3. Ledbetter JA, et al. 1979. Immunol. Rev. 47:63. (IP)
  4. Simon DI, et al. 2000. J. Clin. Invest. 105:293. (IHC)
  5. Seaman WE. 1983. J. Immunol. 130:1713. (CMCD)
  6. Cornet A, et al. 2001. P. Natl. Acad. Sci. USA 98:13306. (IHC)
  7. Tsuboi S and Fukuda M. 1998. J. Biol. Chem. 273:30680. (WB) PubMed
  8. Liu F, et al. 2012. Blood. 119:3295. PubMed
  9. Pelletier AN, et al. 2012. J. Immunol. 188:5561. PubMed
  10. Radtke AJ, et al. 2020. Proc Natl Acad Sci U S A. 117:33455-65. (SB) PubMed
  11. Radtke AJ, et al. 2022. Nat Protoc. 17:378-401. (SB) PubMed
Product Citations
  1. Johnson DC, et al. 2018. Nat Med. 24:1151. PubMed
  2. Yu X, et al. 2020. Nat Commun. 11:1110. PubMed
  3. Xu X, et al. 2020. Chin Med. 15:33. PubMed
  4. Shakya S, et al. 2020. MethodsX. 7:101027. PubMed
  5. J Gautam, X Zhang, Y Yao 2016. Sci Rep. 6:36450. PubMed
  6. Li Y, et al. 2020. Nat Commun. 2.350694444. PubMed
  7. Gabitova-Cornell L, et al. 2020. Cancer Cell. 38(4):567-583.e11. PubMed
  8. Garo LP, et al. 2021. Nat Commun. 12:2419. PubMed
  9. Hutton C, et al. 2021. Cancer Cell. 39:1227. PubMed
  10. Sefik E, et al. 2022. Nature. 606:585. PubMed
  11. Leinroth AP, et al. 2022. Cell Rep. 39:110785. PubMed
  12. Doughty D, et al. 2022. Exp Biol Med (Maywood). 247:1433. PubMed
  13. Du M, et al. 2022. Cancer Sci. 113:2974. PubMed
  14. Grégoire C, et al. 2022. Immunity. 55:1216. PubMed
  15. Tao X, et al. 2022. EMBO J. 41:e110439. PubMed
  16. Blanco LP, et al. 2022. Arthritis Rheumatol. 74:1971. PubMed
  17. Li X, et al. 2022. Cell Mol Gastroenterol Hepatol. 14:1077. PubMed
  18. Hindy G, et al. 2022. J Clin Invest. 132: . PubMed
  19. Roy IM, et al. 2022. iScience. 25:105171. PubMed
  20. Mendivil-Perez M, et al. 2022. Med Oncol. 40:15. PubMed
  21. Chen X, et al. 2022. J Extracell Vesicles. 11:e12279. PubMed
  22. Zheng Z, et al. 2022. Cells. 11: . PubMed
  23. Voit RA, et al. 2023. Nat Immunol. 24:69. PubMed
  24. Varshney R, et al. 2023. iScience. 26:105750. PubMed
  25. Cheng P, et al. 2023. Pharmacol Res. 188:106643. PubMed
  26. Jin SM, et al. 2023. Nat Nanotechnol. :. PubMed
  27. Chen L, et al. 2023. Bioeng Transl Med. 8:e10377. PubMed
  28. Stravokefalou V, et al. 2023. Front Immunol. 13:1014802. PubMed
  29. Zhao Y, et al. 2023. Sci Adv. 9:eabo1360. PubMed
  30. Liu X, et al. 2022. Pain. 163:508. PubMed
  31. González H, et al. 2022. Cell. 185:729. PubMed
  32. Mecklenburg J, et al. 2022. Brain Behav Immun. 101:246. PubMed
  33. Na E, et al. 2022. Am J Physiol Lung Cell Mol Physiol. 322:L550. PubMed
  34. Ma Y, et al. 2022. Am J Physiol Heart Circ Physiol. 322:H622. PubMed
  35. Ajay AK, et al. 2022. Cell Rep. 38:110473. PubMed
  36. Mise Y, et al. 2022. Carcinogenesis. 43:647. PubMed
  37. Pfeifhofer-Obermair C, et al. 2022. Bio Protoc. 12:e4378. PubMed
  38. Hanuscheck N, et al. 2022. J Exp Med. 219:. PubMed
  39. Klawitter M, et al. 2022. Int J Mol Sci. 23:. PubMed
  40. Zheng Y, et al. 2022. Proc Natl Acad Sci U S A. 119:e2121077119. PubMed
  41. Bowley TY, et al. 2022. Cancer Res Commun. 2:1436. PubMed
  42. Chen Y, et al. 2022. Am J Cancer Res. 12:5286. PubMed
  43. Zhang Y, et al. 2023. Invest Ophthalmol Vis Sci. 64:1. PubMed
  44. Sparbier CE, et al. 2023. Nat Cell Biol. 25:258. PubMed
  45. Li Y, et al. 2023. Adv Mater. 35:e2208923. PubMed
  46. Li M, et al. 2023. Front Immunol. 14:1087923. PubMed
  47. Chen H, et al. 2023. Nat Commun. 14:941. PubMed
  48. Ferriz M, et al. 2023. STAR Protoc. 4:102079. PubMed
  49. Volkova MV, et al. 2023. Int J Mol Sci. 24:. PubMed
  50. Solier S, et al. 2023. Int J Mol Sci. 24:. PubMed
  51. Li L, et al. 2023. iScience. 26:106095. PubMed
  52. Cheong LY, et al. 2023. Nat Commun. 14:1213. PubMed
  53. Xu H, et al. 2023. Acta Pharm Sin B. 13:678. PubMed
  54. Kozlovski S, et al. 2023. Front Immunol. 13:1041552. PubMed
  55. Rege SV, et al. 2023. Commun Biol. 6:292. PubMed
  56. Wang Y, et al. 2023. J Nanobiotechnology. 21:109. PubMed
  57. Zhang X, et al. 2023. Front Immunol. 14:1116749. PubMed
  58. Kim BH, et al. 2023. Sci Rep. 13:6577. PubMed
  59. Li T, et al. 2023. Nat Commun. 14:2498. PubMed
  60. Kase N, et al. 2023. Front Cell Dev Biol. 11:1022081. PubMed
  61. Huang T, et al. 2023. Cell Death Dis. 14:354. PubMed
  62. Guo X, et al. 2023. Mol Immunol. 160:32. PubMed
  63. Wang X, et al. 2023. Nature. 618:808. PubMed
  64. Akasaka H, et al. 2023. JCI Insight. 8:. PubMed
  65. Nederlof R, et al. 2022. Front Immunol. 13:908023. PubMed
  66. Kataru RP, et al. 2021. Sci Signal. 14:. PubMed
  67. Li Z, et al. 2022. Nat Commun. 13:1845. PubMed
  68. El-Hindi K, et al. 2022. Int J Mol Sci. 23:. PubMed
  69. Qi Z, et al. 2022. Nat Commun. 13:182. PubMed
  70. Ma J, et al. 2020. Adv Sci (Weinh). 7:2000609. PubMed
  71. Sharma GP, et al. 2021. PLoS One. 16:e0259042. PubMed
  72. Huang Z et al. 2017. Cell metabolism. 26(3):493-508 . PubMed
  73. McGill BE et al. 2018. The Journal of Neuroscience. 38(1):200-219 . PubMed
  74. Hofmann I, et al. 2022. J Pharmacol Exp Ther. Online ahead of print. PubMed
  75. Hulsebus HJ, et al. 2022. Front Immunol. 13:884719. PubMed
  76. Li X, et al. 2022. Nat Commun. 13:2794. PubMed
  77. Zhu H, et al. 2018. Elife. 7:. PubMed
  78. Abdala-Valencia H, et al. 2014. Am J Physiol Lung Cell Mol Physiol. 307:482. PubMed
  79. Rodriguez-García A, et al. 2021. Nat Commun. 12:877. PubMed
  80. Tcheng M, et al. 2021. Blood. 137:3518. PubMed
  81. Prado C, et al. 2021. J Neuroinflammation. 18:292. PubMed
  82. Wang M, et al. 2022. Theranostics. 12:4513. PubMed
  83. Adachi Y, et al. 2022. Nat Commun. 13:5117. PubMed
  84. Bauer KM, et al. 2022. JCI Insight. 7:. PubMed
  85. Sepe JJ, et al. 2022. JACC Basic Transl Sci. 7:915. PubMed
  86. Rao E, et al. 2021. Sci Immunol. 6:. PubMed
  87. Saito S, et al. 2020. Nutrients. 12:. PubMed
  88. Liu X, et al. 2020. Nature. . PubMed
  89. Liang W, et al. 2020. Nat Commun. 4.563888889. PubMed
  90. Shao Y, et al. 2019. Diabetes. 68:2131. PubMed
  91. Lee AK, et al. 2020. Radiat Res. 193:305. PubMed
  92. Choi H et al. 2019. Cell Rep. 27(3):806-819 . PubMed
  93. Agelidis A, et al. 2019. Front Immunol. 10:500. PubMed
  94. Neumann AM et al. 2017. PloS one. 12(11):e0187330 . PubMed
  95. Pan D, et al. 2022. Cancer Res. 82:2748. PubMed
  96. Zhang Q, et al. 2019. PLoS Biol. 17:e3000330. PubMed
  97. Tsuchiya N, et al. 2020. Cell Reports. 29(1):162-175.e9.. PubMed
  98. Ohigashi I, et al. 2020. Cell Reports. 29(9):2901-2916.e6.. PubMed
  99. Zhao G, et al. 2020. Sci Adv. 6:00. PubMed
  100. Evren E, et al. 2020. Immunity. 54(2):259-275.e7. PubMed
  101. Wosczyna MN, et al. 2021. Cell Stem Cell. 28(7):1323-1334.e8. PubMed
  102. Pan H, et al. 2020. Mol Psychiatry. . PubMed
  103. Wang X, et al. 2021. Front Cell Dev Biol. 632805:9. PubMed
  104. Ihara S, et al. 2022. PLoS Negl Trop Dis. 16:e0010323. PubMed
  105. Talma N, et al. 2021. Aging Cell. 20:e13450. PubMed
  106. Rolfes S, et al. 2020. Neurobiol Dis. 144:105024. PubMed
  107. Zhang Z, et al. 2021. Oncoimmunology. 10:1912472. PubMed
  108. Han C, et al. 2021. Cell Reports. 34(6):108706. PubMed
  109. Zhang C, et al. 2020. Cell Metabolism. 31(1):148-161.e5.. PubMed
  110. Lu Y, et al. 2020. Cell. 180(6):1081-1097. PubMed
  111. Meixiong J et al. 2019. Immunity. 50(5):1163-1171 . PubMed
  112. Xiao X, et al. 2019. Cell Discov. 5:2. PubMed
  113. Dai B, et al. 2022. Theranostics. 12:7603. PubMed
  114. Francian A, et al. 2021. J Drug Target. 29:754. PubMed
  115. Johansen AZ, et al. 2022. Pharmaceutics. 14:. PubMed
  116. Emgård J, et al. 2018. Immunity. 143:419. PubMed
  117. Parada-Kusz M, et al. 2018. Dis Model Mech. 11:. PubMed
  118. Feng Y, et al. 2018. Kidney Dis (Basel). 4:95. PubMed
  119. Wosczyna MN et al. 2019. Cell Rep. 27(7):2029-2035 . PubMed
  120. Plein A, et al. 2018. Nature. 562:223. PubMed
  121. Kobayashi S, et al. 2019. J Immunol. 203:1447. PubMed
  122. Green DP, et al. 2019. Neuron. 101:412. PubMed
  123. Davidson S, et al. 2020. Cell Reports. 31(7):107628. PubMed
  124. Kucinski I, et al. 2020. EMBO J. :e104983. PubMed
  125. Müller A, et al. 2020. J Clin Invest. 5765:130. PubMed
  126. Liang Z, et al. 2020. Pain. 161:2089. PubMed
  127. Zhang W, et al. 2021. Cell Prolif. 54:e13058. PubMed
  128. Gui J, et al. 2020. Nat Cancer. 1:603. PubMed
  129. Hore ZL, et al. 2021. Wellcome Open Res. 6:68. PubMed
  130. Dane EL, et al. 2022. Nat Mater. 21:710. PubMed
  131. Yao L, et al. 2021. J Bone Miner Res. 36:1159. PubMed
  132. Koujah L, et al. 2021. Ocul Surf. 21:238. PubMed
  133. Kumari A, et al. 2022. Sci Rep. 12:15273. PubMed
  134. Li P, et al. 2021. Nat Immunol. 22:1107. PubMed
  135. Zhang X, et al. 2022. Cells. 11:. PubMed
  136. Kusuyama J, et al. 2021. Cell Metabolism. 33(5):939-956.e8. PubMed
  137. Deng Z, et al. 2017. Oncogene. 36:639. PubMed
  138. Barman PK, et al. 2019. J Immunol. 202:2720. PubMed
  139. Lim D, et al. 2018. Front Physiol. 9:47. PubMed
  140. Luo W, et al. 2022. Front Immunol. 13:816761. PubMed
  141. Zein HS, et al. 2022. Sci Rep. 12:4834. PubMed
  142. Srivastava S, et al. 2019. Cancer Cell. 35:489. PubMed
  143. Wang ECE, et al. 2019. Cell Stem Cell. 24:654. PubMed
  144. Cervera–Carrascon V, et al. 2020. Oncoimmunology. 9:1761229. PubMed
  145. Zhang K, et al. 2014. PLoS Pathog. 10:1004385. PubMed
  146. Mencarelli A, et al. 2016. Sci Rep. 6:30802. PubMed
  147. Lu X, et al. 2016. Nat Commun. 7: 12719. PubMed
  148. Hu J, et al. 2020. Theranostics. 7.154166667. PubMed
  149. Li J, et al. 2020. Elife. 9:00. PubMed
  150. Rosa JM, et al. 2021. British Journal of Pharmacology. . PubMed
  151. Derecka M, et al. 2020. Nat Immunol. 261:21. PubMed
  152. Morimoto A, et al. 2021. Nat Commun. 12:2136. PubMed
  153. Poillet-Perez L, et al. 2020. Nat Cancer. 1:923. PubMed
  154. Du Y, et al. 2022. Nat Commun. 13:231. PubMed
  155. Gañán-Gómez I, et al. 2022. Nat Med. . PubMed
  156. Chin AL, et al. 2021. Nat Commun. 12:5138. PubMed
  157. Zeng Q, et al. 2022. Front Immunol. 13:740805. PubMed
  158. Ye P, et al. 2022. Front Cardiovasc Med. 8:810477. PubMed
  159. Brigas HC, et al. 2021. Cell Reports. 36(9):109574. PubMed
  160. Zhu H, et al. 2021. Cell Metabolism. :. PubMed
  161. Nguyen PT, et al. 2020. Cell. 182(2):388-403.e15. PubMed
  162. Liu CY, et al. 2020. Cell Rep. 33:108275. PubMed
  163. Wan X, et al. 2018. Nature. 560:107. PubMed
  164. Al–Zaher AA, et al. 2018. Mol Ther Oncolytics. 0.376388889. PubMed
  165. Hepler C et al. 2018. eLife. 7 pii: e39636. PubMed
  166. Goldfarb Y, et al. 2021. J Exp Med. 218:. PubMed
  167. Cai Y, et al. 2019. Cell Rep. 27:3034. PubMed
  168. Crowell PD et al. 2019. Cell Rep. 28(6):1499-1510 . PubMed
  169. Maetzig T, et al. 2017. Mol Ther. 25:606. PubMed
  170. Burr ML, et al. 2019. Cancer Cell. 36:385. PubMed
  171. Wang F, et al. 2019. MAbs. 12:1685350. PubMed
  172. Ji DX, et al. 2019. Nat Microbiol. 1.644444444. PubMed
  173. Liu S, et al. 2020. Cell Host & Microbe. 26(6):779-794.e8.. PubMed
  174. Liang J, et al. 2020. Sci Adv. 6:eabc3646. PubMed
  175. Watanabe Y, et al. 2020. J Biol Chem. 295:17632. PubMed
  176. Engler AE, et al. 2020. Cell Reports. 33(13):108553. PubMed
  177. Ruan C, et al. 2020. Brain Behav Immun. 83:180. PubMed
  178. Sefik E, et al. 2021. Nat Biotechnol. . PubMed
  179. Rashid MH, et al. 2021. Oncol Rep. 45:1171. PubMed
  180. Jiang Y, et al. 2021. Cell Death Differ. 28:3009. PubMed
  181. Agelidis A, et al. 2021. JCI Insight. 6: . PubMed
  182. Monaghan KL, et al. 2020. J Vis Exp. . PubMed
  183. Yamakawa D, et al. 2021. Cell Reports. 34(10):108817. PubMed
  184. Galle-Treger L, et al. 2016. Nat Commun. 7:13202. PubMed
  185. Coronel MM, et al. 2020. Sci Adv. 6:eaba5573. PubMed
  186. Pundir P, et al. 2020. Cell Host & Microbe. 26(1):114-122. PubMed
  187. Gastelum‐Aviña P et al. 2016. Journal of immunological methods. 438:42-50 . PubMed
  188. Zhou J, et al. 2019. Nat Commun. 10:2427. PubMed
  189. Yu X, et al. 2019. Nat Commun. 10:574. PubMed
  190. Su S et al. 2018. Cell. 175(2):442-457 . PubMed
  191. Milner MT, et al. 2022. STAR Protoc. 3:101295. PubMed
  192. Zhang X, et al. 2021. Proc Natl Acad Sci U S A. 118:. PubMed
  193. Xiao L, et al. 2021. Clin Cancer Res. 27:4338. PubMed
  194. Kotas ME, et al. 2022. JCI Insight. :. PubMed
  195. Wang Z et al. 2018. Immunity. 49(1):80-92 . PubMed
  196. Sarvi S et al. 2018. Cell chemical biology. 25(12):1456-1469 . PubMed
  197. Ito K, et al. 2014. Proc Natl Acad Sci U S A. 111:3080. PubMed
  198. Saunders L, et al. 2015. Sci Transl Med. 7: 302ra136. PubMed
  199. Jiang Q, et al. 2020. JCI Insight. 5:00. PubMed
  200. Hasegawa T, et al. 2020. Sci Rep. 10:13480. PubMed
  201. Johnson DC, et al. 2020. Cell Death Dis. 0.894444444. PubMed
  202. Li CM, et al. 2020. Cell Reports. 33(13):108566. PubMed
  203. Zhang L, et al. 2021. iScience. 24(9):102942. PubMed
  204. Hu Y, et al. 2021. Cell Death Dis. 12:743. PubMed
  205. Minhas PS, et al. 2021. Nature. 590:122. PubMed
  206. Zhang X, et al. 2021. Mol Cancer Res. 19:1076. PubMed
  207. Liu S, et al. 2022. J Neuroinflammation. 19:35. PubMed
  208. Xiao Y, et al. 2022. Nat Commun. 13:758. PubMed
  209. Ali S, et al. 2021. PLoS One. 16:e0246646. PubMed
  210. Yang Z, et al. 2021. Nat Commun. 12:4852. PubMed
  211. Long JT, et al. 2022. Elife. 11:. PubMed
  212. Bravo-Caparrós I, et al. 2020. FASEB J. 34:5951. PubMed
  213. Zhang P, et al. 2022. Nat Commun. 13:1588. PubMed
  214. Sirvinskas D, et al. 2022. iScience. 25:104202. PubMed
  215. Wang W, et al. 2021. J Am Heart Assoc. 10:e019142. PubMed
  216. Song J, et al. 2021. Am J Physiol Heart Circ Physiol. 320:H323. PubMed
  217. Zeis P, et al. 2020. Immunity. 53:775. PubMed
  218. Ben-Yehuda H, et al. 2021. Mol Neurodegener. 16:39. PubMed
  219. Kim H, et al. 2020. Biomed Rep. 0.589583333. PubMed
  220. Qi F, et al. 2019. Front Microbiol. 2.140277778. PubMed
  221. Yu JM, et al. 2019. Nat Commun. 4.388888889. PubMed
  222. Li Z, et al. 2022. Nat Commun. 13:6321. PubMed
  223. Hou Y, et al. 2021. Sci Transl Med. 13:. PubMed
  224. Xu G, et al. 2022. Front Pharmacol. 13:896601. PubMed
  225. Zhou J, et al. 2022. Int J Oncol. 61: . PubMed
  226. Ovadya Y, et al. 2018. Nat Commun. 9:5435. PubMed
  227. Zheng B, et al. 2021. Bioact Mater. 6:3879. PubMed
  228. Ferrer-Font L, et al. 2020. Elife. 9:. PubMed
  229. Sakai H, et al. 2022. iScience. 25:103928. PubMed
  230. Walker MT, et al. 2021. Front. Allergy. 2:. PubMed
  231. Kataru RP, et al. 2022. Front Aging. 3:864860. PubMed
  232. Pan Y, et al. 2021. Br J Pharmacol. 178:4907. PubMed
  233. Tomimatsu M, et al. 2022. Sci Rep. 12:16656. PubMed
  234. Fan ZP, et al. 2021. Front Immunol. 12:743354. PubMed
  235. Okada R, et al. 2021. EBioMedicine. 67:103345. PubMed
  236. Chen M, et al. 2019. Cell Stem Cell. 25:501. PubMed
  237. Sema Kurtulus et al. 2018. Immunity. 50(1):181-194 . PubMed
  238. Liu L et al. 2018. Cell stem cell. 23(4):544-556 . PubMed
  239. Zhao N, et al. 2018. J Clin Invest. 26:84. PubMed
  240. Hameed H, et al. 2022. Int J Mol Sci. 23:. PubMed
  241. Ding R, et al. 2022. J Neuroinflammation. 19:137. PubMed
  242. Liu R, et al. 2020. Eur J Vasc Endovasc Surg. 60:254. PubMed
  243. Ding L et al. 2018. Cell reports. 25(11):2972-2980 . PubMed
  244. Hao T, et al. 2019. Nat Commun. 10:3665. PubMed
  245. Zegarra‐Ruiz DF et al. 2018. Cell host & microbe. 25(1):113-127 . PubMed
  246. Chao Y, et al. 2020. Sci Adv. 6:eaaz4204. PubMed
  247. Kataru RP, et al. 2019. Cancer Immunol Res. 7:1345. PubMed
  248. Krivtsov AV, et al. 2020. Cancer Cell. 36(6):660-673.e11.. PubMed
  249. Hu X, et al. 2020. Neoplasia. 1.290972222. PubMed
  250. Cerina M, et al. 2017. Brain Behav Immun. 59:103-117. PubMed
  251. Simoes Eugénio M, et al. 2020. Cancers (Basel). 12:00. PubMed
  252. Chen L, et al. 2021. Theranostics. 11:6668. PubMed
  253. Sugita Y, et al. 2021. Oncol Rep. 45:. PubMed
  254. Banskota S, et al. 2021. Inflamm Bowel Dis. 27:914. PubMed
  255. Ruan Y, et al. 2022. Exp Ther Med. 23:47. PubMed
  256. Wang R, et al. 2022. J Immunother Cancer. 10:. PubMed
  257. Liao X, et al. 2022. JCI Insight. 7:. PubMed
  258. Kelley WJ, et al. 2022. JCI Insight. 7: . PubMed
  259. Sharma R, et al. 2021. J Neuroinflammation. 72:18. PubMed
  260. Watanabe Y, et al. 2020. J Biol Chem. . PubMed
  261. Sheng J, et al. 2021. eLife. 10:00. PubMed
  262. Tr änkner D, et al. 2019. Cell Rep. 29:791. PubMed
  263. Lee C, et al. 2020. Front Immunol. 11:77. PubMed
  264. Eckert EC, et al. 2020. Mol Ther Oncolytics. 0.710416667. PubMed
  265. Poillet–Perez L, et al. 2018. Nature. 563:569. PubMed
  266. Padhye A, et al. 2019. Sci Rep. 9:4819. PubMed
  267. Zhou Y, et al. 2022. Theranostics. 12:5488. PubMed
  268. Sheng D, et al. 2022. J Immunother Cancer. 10:. PubMed
  269. El-Obeid A, et al. 2021. Exp Ther Med. 22:1081. PubMed
  270. Le TM et al. 2018. Journal of neurochemistry. 145(2):139-153 . PubMed
  271. Lee EKS, et al. 2018. Cell Host Microbe. 23:121. PubMed
  272. Shao Y, et al. 2019. Stem Cells. 37:1331. PubMed
  273. Krotova K, et al. 2019. Mol Ther Oncolytics. 15:166. PubMed
  274. Gupta R, et al. 2020. Cell Stem Cell. 26:527. PubMed
  275. Li M, et al. 2020. Nat Commun. 4051:11. PubMed
  276. Spiljar M, et al. 2021. Cell Metab. 33:2231. PubMed
  277. Zhang L, et al. 2021. Mol Ther. 29:744. PubMed
  278. Andreata F, et al. 2021. STAR Protoc. 2:100831. PubMed
  279. Ichinose M, et al. 2021. Sci Rep. 7200:11. PubMed
  280. Zhang B, et al. 2021. Front Neurol. 607370:12. PubMed
  281. Dingler FA, et al. 2020. Mol Cell. . PubMed
  282. Wan Y, et al. 2020. Cell Rep. 33:108346. PubMed
  283. Badgujar DC, et al. 2020. PLoS Pathog. 16:e1009016. PubMed
  284. Ma Y, et al. 2020. Front Immunol. 11:586685. PubMed
  285. Pessoa Rodrigues C, et al. 2020. Sci Adv. 6:eaaz4815. PubMed
  286. Guarnerio J, et al. 2018. Nat Commun. 9:66. PubMed
  287. Wolf Y, et al. 2019. Cell. 179:219. PubMed
  288. Li CY, et al. 2022. Int J Mol Sci. 23:. PubMed
  289. Wang H, et al. 2022. J Cancer. 13:2126. PubMed
  290. Zhang SJ, et al. 2021. Adv Sci (Weinh). 8:2003410. PubMed
RRID
AB_312972 (BioLegend Cat. No. 103107)
AB_312972 (BioLegend Cat. No. 103108)

Antigen Details

Structure
Protein tyrosine phosphatase (PTP) family, 180-240 kD
Distribution

All hematopoietic cells except mature erythrocytes and platelets

Function
Phosphatase, T and B cell activation
Ligand/Receptor
Galectin-1, CD2, CD3, CD4, TCR, CD22, Thy-1
Cell Type
B cells, Dendritic cells, Mesenchymal Stem Cells, Tregs
Biology Area
Cell Biology, Immunology, Inhibitory Molecules, Innate Immunity, Neuroscience, Neuroscience Cell Markers, Stem Cells
Molecular Family
CD Molecules
Antigen References

1. Barclay A, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Trowbridge IS, et al. 1993. Annu. Rev. Immunol. 12:85.
3. Kishihara K, et al. 1993. Cell 74:143.
4. Pulido R, et al. 1988. J. Immunol. 140:3851.

Gene ID
19264 View all products for this Gene ID
UniProt
View information about CD45 on UniProt.org

Other Formats

View All CD45 Reagents Request Custom Conjugation
Description Clone Applications
APC anti-mouse CD45 30-F11 FC
Biotin anti-mouse CD45 30-F11 FC
FITC anti-mouse CD45 30-F11 FC
PE anti-mouse CD45 30-F11 FC
PE/Cyanine5 anti-mouse CD45 30-F11 FC
Purified anti-mouse CD45 30-F11 FC,IHC-F,CyTOF®,IP,CMCD,IHC,WB
PE/Cyanine7 anti-mouse CD45 30-F11 FC
APC/Cyanine7 anti-mouse CD45 30-F11 FC
Alexa Fluor® 488 anti-mouse CD45 30-F11 FC,SB
Alexa Fluor® 647 anti-mouse CD45 30-F11 FC,ICC,IHC,3D IHC,SB
Pacific Blue™ anti-mouse CD45 30-F11 FC
Alexa Fluor® 700 anti-mouse CD45 30-F11 FC,SB
PerCP/Cyanine5.5 anti-mouse CD45 30-F11 FC
PerCP anti-mouse CD45 30-F11 FC
Alexa Fluor® 594 anti-mouse CD45 30-F11 IHC-F,FC,3D IHC
Brilliant Violet 421™ anti-mouse CD45 30-F11 FC,SB
Brilliant Violet 570™ anti-mouse CD45 30-F11 FC
Brilliant Violet 510™ anti-mouse CD45 30-F11 FC
Brilliant Violet 605™ anti-mouse CD45 30-F11 FC
Purified anti-mouse CD45 (Maxpar® Ready) 30-F11 FC,CyTOF®
PE/Dazzle™ 594 anti-mouse CD45 30-F11 FC
Brilliant Violet 711™ anti-mouse CD45 30-F11 FC
Brilliant Violet 785™ anti-mouse CD45 30-F11 FC
Brilliant Violet 650™ anti-mouse CD45 30-F11 FC
APC/Fire™ 750 anti-mouse CD45 30-F11 FC
Brilliant Violet 750™ anti-mouse CD45 30-F11 FC
TotalSeq™-A0096 anti-mouse CD45 30-F11 PG
TotalSeq™-B0096 anti-mouse CD45 30-F11 PG
Ultra-LEAF™ Purified anti-mouse CD45 30-F11 FC,CyTOF®,IP,CMCD,IHC,WB
Spark Blue™ 550 anti-mouse CD45 30-F11 FC
Spark NIR™ 685 anti-mouse CD45 30-F11 FC
TotalSeq™-C0096 anti-mouse CD45 30-F11 PG
Spark YG™ 570 anti-mouse CD45 30-F11 IHC-F
PE/Fire™ 640 anti-mouse CD45 30-F11 FC
APC/Fire™ 810 anti-mouse CD45 30-F11 FC
PE/Fire™ 700 anti-mouse CD45 30-F11 FC
Spark Violet™ 538 anti-mouse CD45 30-F11 FC
Spark YG™ 593 anti-mouse CD45 30-F11 FC
Spark Blue™ 574 anti-mouse CD45 Antibody 30-F11 FC
Spark Blue™ 515 anti-mouse CD45 30-F11 FC
Spark UV™ 387 anti-mouse CD45 30-F11 FC
PE/Fire™ 810 anti-mouse CD45 30-F11 FC
Spark Red™ 718 anti-mouse CD45 (Flexi-Fluor™) 30-F11 FC
Spark PLUS UV395™ anti-mouse CD45 30-F11 FC
Go To Top Version: 2    Revision Date: 05.14.2013

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

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8999 BioLegend Way, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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