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PE anti-mouse CD98 (4F2) Antibody

Pricing & Availability
Clone
RL388 (See other available formats)
Regulatory Status
RUO
Other Names
4F2, Ly10,
Isotype
Rat IgG2a, κ
Ave. Rating
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Product Citations
publications
RL388_PE_082808.jpg
C57BL/6 splenocytes stained with RL388 PE
  • RL388_PE_082808.jpg
    C57BL/6 splenocytes stained with RL388 PE
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128207 50 µg 113 CHF
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128208 200 µg 335 CHF
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Description

CD98 is a cell surface glycoprotein of 125 kd consisting of an 85 kd heavy chain and a 40 kd light chain.It is expressed on T, B, NK cells, granulocytes and many cell lines and tumor cells.CD98 has been shown to be involved in sodium-dependent calcium flux in muscles cells and lymphocyte activation.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Subline of mouse T lymphoma EL4
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.06 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application References

(PubMed link indicates BioLegend citation)
  1. Luscher B, et al. 1985. J. Immunol. 135 :3951
  2. MacDonald HR, et al. 1985. J. Immunol. 135 :3944
Product Citations
  1. Wu J et al. 2017. Immunity. 47(6):1114-1128 . PubMed
  2. Wight AE, et al. 2022. Proc Natl Acad Sci U S A. 119:e2200757119. PubMed
  3. Dvorscek AR, et al. 2022. EMBO Rep. 23:e54677. PubMed
  4. Pandit M, et al. 2023. Nat Commun. 14:2593. PubMed
  5. Chappaz S, et al. 2021. Cell Reports. 36(3):109430. PubMed
  6. Finicle BT, et al. 2018. J Cell Sci. 131. PubMed
  7. Paiva RA, et al. 2021. Cell Reports. 35(2):108967. PubMed
  8. Kubiniok P, et al. 2019. Mol Cell Proteomics. 18:408. PubMed
  9. , et al. 2021. Eur J Immunol. 51:2708. PubMed
  10. Frost JN, et al. 2021. Med (N Y). 2:164. PubMed
  11. Chatterjee S et al. 2017. Cell metabolism. 27(1):85-100 . PubMed
  12. Wuggenig P, et al. 2020. Commun Biol. 3:130. PubMed
  13. Yu W, et al. 2022. Nat Commun. 13:3544. PubMed
  14. Cao G, et al. 2016. J Leukoc Biol. 100: 1181 - 1189. PubMed
  15. Timilshina M, et al. 2020. Cell Reports. 27(10):2948-2961.e7.. PubMed
  16. Tsai S, et al. 2018. Cell Metab. 28:922. PubMed
RRID
AB_2190813 (BioLegend Cat. No. 128207)
AB_2190813 (BioLegend Cat. No. 128208)

Antigen Details

Structure
Cell surface glycoprotein of 125 kd consisting of an 85 Kd heavy chain and a 40 kd light chain.
Distribution

Expressed on T cells, B cells , NK cells, granulocytes, etc.

Function
Regulatory role in amino acid transport system. Modulate sodium-dependent calcium flux and cell activation
Cell Type
B cells, Granulocytes, NK cells, T cells
Biology Area
Immunology, Innate Immunity
Molecular Family
CD Molecules
Antigen References

1. Luscher B, et al. 1985. J. Immunol. 135 :3951
2. MacDonald HR, et al. 1985. J. Immunol. 135 :3944

Gene ID
17254 View all products for this Gene ID
Specificity (DOES NOT SHOW ON TDS):
CD98
Specificity Alt (DOES NOT SHOW ON TDS):
CD98
App Abbreviation (DOES NOT SHOW ON TDS):
FC
UniProt
View information about CD98 on UniProt.org

Related FAQs

What type of PE do you use in your conjugates?
We use R-PE in our conjugates.
Go To Top Version: 1    Revision Date: 11.30.2012

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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