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- Clone
- K125H4 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- Mas-related G-protein coupled receptor member X2, MRGPRX2
- Isotype
- Mouse IgG2b, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
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Human MRGX2 transfected CHO cells were stained with purified MRGX2 (clone K125H4, filled histogram) or purified mouse IgG2b, κ isotype control (open histogram), followed by anti-mouse IgG PE.
| Cat # | Size | Price | Quantity Check Availability | Save | ||
|---|---|---|---|---|---|---|
| 359002 | 100 µg | 335 CHF | ||||
MRGX2 (Mas-related G-protein coupled receptor member X2) is a 36 kD, seven transmembrane protein expressed on mast cells and sensory neurons from the dorsal root ganglia. MRGX2 is involved in mast cell-degranulation, and may regulate the function and development of sensory neurons. Originally described as an orphan receptor, it has been reported MRGX2 binds defensins and costistatin.
Product DetailsProduct Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- DNA vaccine containing the full length gene of human MRGX2
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
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FC - Quality tested
- Recommended Usage
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Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.5 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Product Citations
-
- RRID
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AB_2562299 (BioLegend Cat. No. 359002)
Antigen Details
- Structure
- Seven transmembrane domains, 36 kD, member of the GPCR family
- Distribution
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Mast cells, sensory neurons from the dorsal root ganglia
- Function
- Involved in mast cell-degranulation, may regulate function and development of sensory neurons
- Interaction
- Coupled to G-proteins Gαq and Gαi
- Ligand/Receptor
- Defensins, cortistatin
- Cell Type
- Mast cells
- Biology Area
- Immunology, Innate Immunity
- Antigen References
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1. Subramanian H, et al. 2013. J. Immunol. 191:345.
2. Subramanian H, et al. 2011. J. Biol. Chem. 286:44739.
3. Yang S, et al. 2005. Gene. 352:30.
4. Robas N, et al. 2003. J. Biol. Chem. 278:44400. - Gene ID
- 117194 View all products for this Gene ID
- Specificity (DOES NOT SHOW ON TDS):
- MRGX2
- Specificity Alt (DOES NOT SHOW ON TDS):
- MRGX2
- App Abbreviation (DOES NOT SHOW ON TDS):
- FC
- UniProt
- View information about MRGX2 on UniProt.org
Other Formats
View All MRGX2 Reagents Request Custom Conjugation| Description | Clone | Applications |
|---|---|---|
| Purified anti-human MRGX2 | K125H4 | FC |
| PE anti-human MRGX2 | K125H4 | FC |
| APC anti-human MRGX2 | K125H4 | FC |
| PE/Cyanine7 anti-human MRGX2 | K125H4 | FC |
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Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
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Purified anti-human MRGX2
Human MRGX2 transfected CHO cells were stained with purified... -
PE anti-human MRGX2
Human MRGX2 transfected CHO cells were stained with MRGX2 (c... -
APC anti-human MRGX2
Human MRGX2 transfected CHO cells were stained with MRGX2 (c... -
PE/Cyanine7 anti-human MRGX2
Human MRGX2 transfected CHO cells were stained with MRGX2 (c...
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