- Clone
- UP-H2 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- CD300e, CMRF35-A5, LMIR6
- Isotype
- Mouse IgG1, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
![UP-H2_APC_CD300e_Antibody_1_121823 UP-H2_APC_CD300e_Antibody_1_121823](https://d1spbj2x7qk4bg.cloudfront.net/Admin/Public/GetImage.ashx?Image=/Files/Images/media_assets/products/product_images/UP-H2_APC_CD300e_Antibody_1_121823-.png&Width=240&Height=300&altFmImage_path=&Compression=90&Crop=5)
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Human peripheral blood monocytes were stained with anti-human CD300e (IREM-2, CMRF35-A5) (clone UP-H2) APC (filled histogram) or mouse IgG1, κ APC isotype control (open histogram) -
Human peripheral blood monocytes were stained with anti-human CD14 PE and anti-human CD300e (IREM-2, CMRF35-A5) (clone UP-H2) APC (left) or mouse IgG1, κ APC isotype control (right).
Cat # | Size | Price | Quantity Check Availability | Save | ||
---|---|---|---|---|---|---|
339711 | 25 tests | 150 CHF | ||||
339712 | 100 tests | 350 CHF |
IREM-2 (immune receptor expressed by myeloid cells 2), also known as CMRF35-A5, LMIR6, CD300Le or CD300e, is a 34 kD type I single transmembrane glycoprotein. It is a member of the CD300 family and of the Ig-superfamily. IREM-2 is expressed on monocyte and myeloid dendritic cells, but not on granulocytes and lymphoid dendritic cells. IREM-2 is an activating receptor through interaction with DAP12.
Product DetailsProduct Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- IREM-IgG fusion protein
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
-
Red Laser (633 nm)
- Application Notes
-
Additional reported applications include: immunoprecipitation and stimulation of TNF-a production by monocytes
-
Application References
(PubMed link indicates BioLegend citation) -
- Aguilar H, et al. 2004. J. Immunol. 173:6703
- Gasiorowski RE, et al. 2013. Immunol Lett. 149:93. PubMed
- RRID
-
AB_3097399 (BioLegend Cat. No. 339711)
AB_3097399 (BioLegend Cat. No. 339712)
Antigen Details
- Structure
- 34 kD, type I transmembrane glycoprotein, CD300 family, Ig superfamily
- Distribution
-
Monocytes, macrophages, dendritic cells
- Function
- Activation of myeloid cells
- Cell Type
- Dendritic cells, Macrophages, Monocytes
- Biology Area
- Immunology
- Molecular Family
- CD Molecules
- Antigen References
-
1. Aguilar H, et al. 2004. J. Immunol. 173:6703
- Gene ID
- 342510 View all products for this Gene ID
- UniProt
- View information about CD300e on UniProt.org
Related Pages & Pathways
Pages
Related FAQs
Other Formats
View All CD300e Reagents Request Custom ConjugationDescription | Clone | Applications |
---|---|---|
PE anti-human CD300e (IREM-2, CMRF35-A5) | UP-H2 | FC |
TotalSeq™-D1279 anti-human CD300e (IREM-2, CMRF35-A5) | UP-H2 | PG |
Spark YG™ 581 anti-human CD300e (IREM-2, CMRF35-A5) | UP-H2 | FC |
PE/Cyanine7 anti-human CD300e (IREM-2, CMRF35-A5) | UP-H2 | FC |
APC anti-human CD300e (IREM-2, CMRF35-A5) | UP-H2 | FC |
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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PE anti-human CD300e (IREM-2, CMRF35-A5)
Human peripheral blood monocytes stained with UP-H2 PE -
TotalSeq™-D1279 anti-human CD300e (IREM-2, CMRF35-A5)
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Spark YG™ 581 anti-human CD300e (IREM-2, CMRF35-A5)
Human peripheral blood monocytes were stained with anti-huma... -
PE/Cyanine7 anti-human CD300e (IREM-2, CMRF35-A5)
Human peripheral blood monocytes were stained with anti-huma... -
APC anti-human CD300e (IREM-2, CMRF35-A5)
Human peripheral blood monocytes were stained with anti-huma... Human peripheral blood monocytes were stained with anti-huma...
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