APC/Fire™ 750 anti-mouse CD191 (CCR1) Antibody, S15040E

Pricing & Availability

Clone: S15040E (See other available formats)
Regulatory Status: RUO
Other Names: CKR1, CKR-1, HM145, CMKBR1, MIP1aR, SCYAR1
Isotype: Rat IgG2b, κ
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Product Citations: publications

S15040E_APCFire750_CD191_Antibody_1_110421 — Thioglycollate-elicited BALB/c mouse peritoneal macrophages were stained with anti-mouse CD191 (clone S15040E) APC/Fire™ 750 (filled histogram) or rat IgG2b, κ APC/Fire™ 750 isotype control (open histogram).

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152511

25 µg

194 CHF

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152512

100 µg

464 CHF

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Description

CD191, also known as CCR1, is a seven transmembrane G protein coupled receptor. It is involved in protecting the host from inflammatory responses and viral/parasite invasion, ligands include macrophage inflammatory protein 1 alpha (MIP-1 alpha, ), regulated on activation normal T expressed and secreted protein (RANTES, CCL5), monocyte chemoattractant protein 3 (MCP-3, CCL7), and myeloid progenitor inhibitory factor-1 (MPIF-1, CCL23).

Product Details

Technical Data Sheet (pdf)

Product Details

Verified Reactivity: Mouse
Antibody Type: Monoclonal
Host Species: Rat
Immunogen: Mouse CCR1-transfectants.
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Preparation: The antibody was purified by affinity chromatography and conjugated with APC/Fire™ 750 under optimal conditions.
Concentration: 0.2 mg/mL
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application: FC - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 5.0 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.

* APC/Fire™ 750 has a maximum excitation of 650 nm and a maximum emission of 774 nm.
Excitation Laser: Red Laser (633 nm)
RRID: AB_2904293 (BioLegend Cat. No. 152511)
AB_2904293 (BioLegend Cat. No. 152512)

Antigen Details

Structure: 41KD, seven transmembrane protein.
Distribution: Macrophages, monocytes, neutrophils and eosinophils.
Function: Regulating migration of cells in response to CCL3, CCL5, CCL7 and CCL23.
Ligand/Receptor: CCL3, CCL5, CCL7 and CCL23.
Cell Type: Eosinophils, Macrophages, Monocytes, Neutrophils
Biology Area: Immunology
Molecular Family: CD Molecules, Cytokine/Chemokine Receptors, GPCR
Antigen References: 1. Lionakis MS, et al. 2012. PLoS Pathog. 8:e1002865.
2. Gilliland CT, et al. 2013. J. Biol. Chem. 288:32194.
3. Gong X, et al. 1997. J. Biol. Chem. 272:11682.
4. Daugherty BL, Springer MS. 1997. Genomics. 41:294.
5. Pakianathan DR, et al. 1997. Biochemistry 36:9642.
Gene ID: 12768 View all products for this Gene ID
UniProt: View information about CD191 on UniProt.org

Documentation

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Related Protocols

Cell Surface Flow Cytometry Staining Protocol

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Description	Clone	Applications

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Other Formats

View All CD191 (CCR1) Reagents Request Custom Conjugation

Description	Clone	Applications
Purified anti-mouse CD191 (CCR1)	S15040E	FC
APC anti-mouse CD191 (CCR1)	S15040E	FC
FITC anti-mouse CD191 (CCR1)	S15040E	FC
PE anti-mouse CD191 (CCR1)	S15040E	FC
PE/Cyanine7 anti-mouse CD191 (CCR1)	S15040E	FC
APC/Fire™ 750 anti-mouse CD191 (CCR1)	S15040E	FC
PE/Dazzle™ 594 anti-mouse CD191 (CCR1)	S15040E	FC

Certificate of Analysis

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Go To Top Version: 1 Revision Date: 11.04.2021

For Research Use Only. Not for diagnostic or therapeutic use.

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