- Clone
- S16017A (See other available formats)
- Regulatory Status
- RUO
- Other Names
- TPOR, c-MPL, MPLV
- Isotype
- Mouse IgG2b, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
Cat # | Size | Price | Quantity Check Availability | Save | ||
---|---|---|---|---|---|---|
393811 | 25 tests | 182 CHF | ||||
393812 | 100 tests | 413 CHF |
CD110 is a type I transmembrane glycoprotein which functions as a receptor for thrombopoietin; binding causes the proliferation and differentiation of megakaroyocytes in addition to the production of platelets and protection of stem cells from apoptosis. CD110 is primarily expressed on hematopoietic stem cells, hematopoietic precursor cells, cells of the megakaryocytic lineage, and platelets.
Product DetailsProduct Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Human CD110 transfectants
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA).
- Preparation
- The antibody was purified by affinity chromatography and conjugated with Brilliant Violet 421™ under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.
Brilliant Violet 421™ excites at 405 nm and emits at 421 nm. The standard bandpass filter 450/50 nm is recommended for detection. Brilliant Violet 421™ is a trademark of Sirigen Group Ltd.
Learn more about Brilliant Violet™.
This product is subject to proprietary rights of Sirigen Inc. and is made and sold under license from Sirigen Inc. The purchase of this product conveys to the buyer a non-transferable right to use the purchased product for research purposes only. This product may not be resold or incorporated in any manner into another product for resale. Any use for therapeutics or diagnostics is strictly prohibited. This product is covered by U.S. Patent(s), pending patent applications and foreign equivalents. - Excitation Laser
-
Violet Laser (405 nm)
- RRID
-
AB_2750510 (BioLegend Cat. No. 393811)
AB_2750510 (BioLegend Cat. No. 393812)
Antigen Details
- Structure
- Type I transmembrane glycoprotein
- Distribution
-
Hematopoietic stem cells, a subfraction of hematopoietic precursor cells, cells of the megakaryocytic lineage, and platelets.
- Function
- Megakaryocytopoiesis and platelet formation
- Interaction
- THPO, ATXN2L, JAK2
- Ligand/Receptor
- Thrombopoietin
- Biology Area
- Immunology
- Molecular Family
- CD Molecules
- Antigen References
-
- Ninos JM, et al. 2006. J. Transl. Med. 16:4-9.
- Broudy VC, et al. 1996. Blood. 88:2026-32.
- Wang X, et al. 2016. Blood. 127:3398-409.
- Gene ID
- 4352 View all products for this Gene ID
- UniProt
- View information about CD110 on UniProt.org
Related Pages & Pathways
Pages
Related FAQs
- What is the F/P ratio range of our BV421™ format antibody reagents?
-
It is lot-specific. On average it ranges between 2-4.
Other Formats
View All CD110 Reagents Request Custom ConjugationDescription | Clone | Applications |
---|---|---|
PE anti-human CD110 | S16017A | FC |
Purified anti-human CD110 | S16017A | FC |
Brilliant Violet 421™ anti-human CD110 | S16017A | FC |
PE/Cyanine7 anti-human CD110 | S16017A | FC |
APC anti-human CD110 | S16017A | FC |
PE/Dazzle™ 594 anti-human CD110 | S16017A | FC |
Customers Also Purchased
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
-
PE anti-human CD110
Resting human platelets were stained with PE anti-human CD11... -
Purified anti-human CD110
Resting human platelets were stained with purified anti-huma... -
Brilliant Violet 421™ anti-human CD110
Resting human platelets were stained with Brilliant Violet 4... -
PE/Cyanine7 anti-human CD110
Resting human platelets were stained with PE/Cyanine7 anti-h... -
APC anti-human CD110
Resting human platelets were stained with APC anti-human CD1... -
PE/Dazzle™ 594 anti-human CD110
Resting human platelets were stained with PE/Dazzle™ 594 ant...
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