GMP APC anti-human CD94 Antibody, CD94, DX22

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Clone: DX22 (See other available formats)
Other Names: KP43
Isotype: Mouse IgG1, κ
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DX22_GMP_APC_CD94_Antibody_082024 — Typical results from human peripheral blood lymphocytes stained either with DX22 APC used at 5 µL/test (filled histogram) or with an isotype control (open histogram).

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260386

100 tests

347 CHF

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Description

CD94 is a 43 kD type II transmembrane glycoprotein also known as KP43. CD94 belongs to the C-type lectin superfamily and is present as a covalently linked heterodimer with NKG2 on the cell surface. CD94 is expressed by NK cells, a subset of γδ T cells, and NKT cells. The CD94/NKG2A complex serves as an inhibitory receptor specific for HLA-class I molecules.

Product Details

Quality Statement This BioLegend’s GMP-RUO reagent is a fluorochrome-labeled monoclonal antibody single reagent for Research Use Only. Suitable for use in laboratory-developed multicolor flow cytometry tests. Single GMP-RUO products can be used in various multicolor flow cytometry combinations. Laboratory need to establish the GMP-RUO performance characteristics in combination with other reagents in normal and pathological samples.

Technical Data Sheet (pdf)

Product Details

Reactivity: Human
Reported Reactivity: African Green, Baboon, Cynomolgus
Antibody Type: Monoclonal
Host Species: Mouse
Immunogen: NK cell line
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA) and a stabilizer.
Preparation: The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
Concentration: 25 µg/mL
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application: FC - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Excitation Laser: Red Laser (633 nm)
Application Notes: Additional reported applications (for the relevant formats) include: immunoprecipitation⁴, inhibition of NK cell-mediated lysis⁵, immunohistochemical staining of acetone-fixed frozen tissue sections, and spatial biology (IBEX)^6,7.

Antigen Details

Structure: C-type lectin, type II transmembrane glycoprotein, covalently associates with NKG2, 43 kD
Distribution: NK cells , T subset
Function: Inhibits NK function
Cell Type: NK cells, T cells
Biology Area: Immunology, Innate Immunity
Molecular Family: CD Molecules
Antigen References: 1. Lopez-Botet M, et al. 1997. Immunol. Rev. 155:165.
2. Moretta A, et al. 1997. Immunol. Rev. 155:105.
Gene ID: 3824 View all products for this Gene ID
UniProt: View information about CD94 on UniProt.org

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Cell Surface Flow Cytometry Staining Protocol

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Pathways

Shedding MICA/B Antigens

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Other Formats

View All CD94 Reagents Request Custom Conjugation

Description	Clone	Applications
APC anti-human CD94	DX22	FC
FITC anti-human CD94	DX22	FC
PE anti-human CD94	DX22	FC,SB
Purified anti-human CD94	DX22	FC,IHC-F
Alexa Fluor® 647 anti-human CD94	DX22	FC
PerCP/Cyanine5.5 anti-human CD94	DX22	FC
PE/Cyanine7 anti-human CD94	DX22	FC
APC/Fire™ 750 anti-human CD94	DX22	FC
PE/Dazzle™ 594 anti-human CD94	DX22	FC
TotalSeq™-A0867 anti-human CD94	DX22	PG
TotalSeq™-C0867 anti-human CD94	DX22	PG
PE/Fire™ 810 anti-human CD94	DX22	FC
TotalSeq™-B0867 anti-human CD94	DX22	PG
TotalSeq™-D0867 anti-human CD94	DX22	PG
APC anti-human CD94	DX22	FC
APC/Cyanine7 anti-human CD94	DX22	FC
FITC anti-human CD94	DX22	FC
GMP APC anti-human CD94	DX22	FC

Certificate of Analysis

Go To Top Version: 1 Revision Date: 09.09.2024

For Research Use Only. Suitable for ex vivo cell processing. Not for injection or diagnostic or therapeutic use.

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

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