- Clone
- S21016F (See other available formats)
- Regulatory Status
- RUO
- Other Names
- T10
- Isotype
- Rat IgG2b, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
Cat # | Size | Price | Quantity Check Availability | Save | ||
---|---|---|---|---|---|---|
165615 | 25 µg | 95 CHF | ||||
165616 | 100 µg | 235 CHF |
CD38, also known as T10, is a 45 kD type II transmembrane glycoprotein. It is an ADP-ribosyl hydrolase expressed at variable levels on hematopoietic cells and in some non-hematopoietic tissues (such as brain, muscle, and kidney). By functioning as both a cyclase and a hydrolase, CD38 mediates lymphocyte activation, adhesion, and the metabolism of cADPR and NAADP. CD31 is thought to be a ligand of CD38.
Product DetailsProduct Details
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- Mouse CD38 transfected cells
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
- Preparation
- The antibody was purified by affinity chromatography and conjugated with Pacific Blue™ under optimal conditions.
- Concentration
- 0.5 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.125 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.
* Pacific Blue™ has a maximum emission of 455 nm when it is excited at 405 nm. Prior to using Pacific Blue™ conjugate for flow cytometric analysis, please verify your flow cytometer's capability of exciting and detecting the fluorochrome.
Alexa Fluor® and Pacific Blue™ are trademarks of Life Technologies Corporation.
View full statement regarding label licenses - Excitation Laser
-
Violet Laser (405 nm)
- Application Notes
-
Clone S21016F can completely block the binding of clone “90” on target cells.
- RRID
-
AB_3106071 (BioLegend Cat. No. 165615)
AB_3106071 (BioLegend Cat. No. 165616)
Antigen Details
- Structure
- ADP-ribosyl hydrolase, 42 kD
- Distribution
-
B cells, NK cells, T cell subset, brain, muscle, kidney
- Function
- Regulation of cellular activation/proliferation, adhesion, metabolism of cADPR and NAADP
- Ligand/Receptor
- CD31, hyaluronic acid
- Cell Type
- B cells, Lymphocytes, NK cells, T cells
- Biology Area
- Cell Biology, Costimulatory Molecules, Immuno-Oncology, Immunology
- Molecular Family
- CD Molecules
- Antigen References
-
- Barclay AN, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
- Shubinsky G, et al. 1997. Immunity. 7:315-24.
- Cesano A, et al. 1998. J Immunol. 160:1106-15.
- Cockayne DA, et al. 1998. Blood. 92:1324-33.
- Gene ID
- 12494 View all products for this Gene ID
- UniProt
- View information about CD38 on UniProt.org
Related Pages & Pathways
Pages
Other Formats
View All CD38 Reagents Request Custom ConjugationDescription | Clone | Applications |
---|---|---|
Purified anti-mouse CD38 | S21016F | FC,IHC-F |
APC anti-mouse CD38 | S21016F | FC |
APC/Fire™ 750 anti-mouse CD38 | S21016F | FC |
FITC anti-mouse CD38 | S21016F | FC |
PE anti-mouse CD38 | S21016F | FC |
PE/Cyanine7 anti-mouse CD38 | S21016F | FC |
PerCP/Cyanine5.5 anti-mouse CD38 | S21016F | FC |
Pacific Blue™ anti-mouse CD38 | S21016F | FC |
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
-
Purified anti-mouse CD38
C57BL/6 mouse splenocytes were stained with purified anti-mo... C57BL/6 mouse frozen spleen section was fixed with 4% parafo... -
APC anti-mouse CD38
C57BL/6 mouse splenocytes were stained with anti-mouse B220 ... -
APC/Fire™ 750 anti-mouse CD38
C57BL/6 mouse splenocytes were stained with anti-mouse B220 ... -
FITC anti-mouse CD38
C57BL/6 mouse splenocytes were stained with anti-mouse B220 ... -
PE anti-mouse CD38
C57BL/6 mouse splenocytes were stained with anti-mouse B220 ... -
PE/Cyanine7 anti-mouse CD38
C57BL/6 mouse splenocytes were stained with anti-mouse B220 ... -
PerCP/Cyanine5.5 anti-mouse CD38
C57BL/6 mouse splenocytes were stained with anti-mouse B220 ... -
Pacific Blue™ anti-mouse CD38
C57BL/6 mouse splenocytes were stained with anti-mouse CD45R...
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