Loading...

PE anti-FOLR1 (Folate Binding Protein) Antibody

Pricing & Availability
Clone
LK26 (See other available formats)
Regulatory Status
RUO
Other Names
Folate receptor alpha, FR-alpha, KB cells FBP, folate binding protein, folate receptor, adult, adult folate-binding protein, ovarian tumor-associated antigen MOv18
Isotype
Mouse IgG2a, κ
Ave. Rating
Submit a Review
Product Citations
publications
LK26_PE_FolateBindingProtein_Antibody_091916
KB cells were stained with anti-FOLR1 (clone LK26) PE (closed histogram) or with mouse IgG2a, κ PE isotype control (open histogram).
  • LK26_PE_FolateBindingProtein_Antibody_091916
    KB cells were stained with anti-FOLR1 (clone LK26) PE (closed histogram) or with mouse IgG2a, κ PE isotype control (open histogram).
See PE spectral data
Cat # Size Price Quantity Check Availability Save
908303 25 tests 153 CHF
Check Availability


Need larger quantities of this item?
Request Bulk Quote
908304 100 tests 360 CHF
Check Availability


Need larger quantities of this item?
Request Bulk Quote
Description

Folate receptor (FOLR1), also known as folate receptor alpha, is a folate-binding protein (FBP) expressed in adults. It has high affinity for folic acid and its metabolites, including 5-methyltetrahydrofolate (5-MTF), the biologically active form of folic acid used for DNA synthesis and the cysteine cycle. FOLR1 mediates intracellular delivery of 5-MTF. FOLR1 is overexpressed in a variety of tumors, including breast, colorectal, and brain.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
This antibody was generated against gestational choriocarcinoma cell line, Lu-75 and detects folate-binding protein (FBP).
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application Notes

This antibody is effective in immunohistochemistry (IHC) and immunoprecipitation (IP).

Positive tissue (human): Frozen placenta or ovarian carcinoma

The LK26 antigen is a 35-40 kD cell surface glycoprotein expressed in normal placenta and gestational choriocarcinoma.

Application References

(PubMed link indicates BioLegend citation)
  1. Hviid TV, et al. 1999. Prenat Diagn. 19: 271.
  2. Chesa-Garin P, et al. 1993. Am J Pathol. 142: 557.
  3. Rettig WJ, et al. 1985. Int J Cancer. 35:469.
Product Citations
  1. Pal S, et al. 2021. Front Chem. 9:721105. PubMed
  2. Zhang B, et al. 2020. Cell Chemical Biology. 28(1):60-69.e7. PubMed
RRID
AB_2629794 (BioLegend Cat. No. 908303)
AB_2629794 (BioLegend Cat. No. 908304)

Related FAQs

What type of PE do you use in your conjugates?
We use R-PE in our conjugates.
Go To Top Version: 1    Revision Date: 09.28.2016

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

BioLegend, the BioLegend logo, and all other trademarks are property of BioLegend, Inc. or their respective owners, and all rights are reserved.

 

8999 BioLegend Way, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

ProductsHere
Login / Register
Remember me
Forgot your password? Reset password?
Create an Account