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- Clone
- QA17A55 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- Common γ chain, γc, IL-2 receptor γ subunit
- Isotype
- Mouse IgG1, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
-
Human peripheral blood lymphocytes were surface stained with anti-human CD132 recombinant (clone QA17A55) PE (filled histogram) or mouse IgG1, κ PE isotype control (open histogram).
| Cat # | Size | Price | Quantity Check Availability | Save | ||
|---|---|---|---|---|---|---|
| 314603 | 25 tests | 122 CHF | ||||
| 314604 | 100 tests | 268 CHF | ||||
CD132 is a 64-70 kD type I transmembrane glycoprotein of the Ig superfamily, also known as common γ chain (γc), or IL-2 receptor γ subunit. It is expressed broadly on T- and B-lymphocytes, NK cells, monocytes, and granulocytes. CD132 is an essential component of cytokine receptors for IL-2, IL-4, IL-7, IL-9, IL-15 and IL-21. Ligand binding induces tyrosine phosphorylation and initiates signaling through a JAK/STAT pathway. CD132 mutation results in X-linked severe combined immune deficiency (XSCID).
Product DetailsProduct Details
- Verified Reactivity
- Human
- Antibody Type
- Recombinant
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
-
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- RRID
-
AB_2890748 (BioLegend Cat. No. 314603)
AB_2890748 (BioLegend Cat. No. 314604)
Antigen Details
- Structure
- Type I transmembrane glycoprotein, Ig superfamily 64-70 kD
- Distribution
-
T cells, B cells, NK, monocytes, granulocytes
- Ligand/Receptor
- Component of cytokine receptors for IL-2, IL-4, IL-7, IL-9, IL-15 and IL-21
- Antigen References
-
1. Corrigall V, et al. 2001. J Immunol. 166(6):4141-7.
- Gene ID
- 3561 View all products for this Gene ID
- UniProt
- View information about CD132 on UniProt.org
Related FAQs
- What type of PE do you use in your conjugates?
- We use R-PE in our conjugates.
Other Formats
View All CD132 Reagents Request Custom Conjugation| Description | Clone | Applications |
|---|---|---|
| PE anti-human CD132 (common γ chain) Recombinant Antibody | QA17A55 | FC |
| Purified anti-human CD132 (common γ chain) Recombinant Antibody | QA17A55 | FC |
Customers Also Purchased
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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PE anti-human CD132 (common γ chain) Recombinant Antibody
Human peripheral blood lymphocytes were surface stained with... -
Purified anti-human CD132 (common γ chain) Recombinant Antibody
Human peripheral blood lymphocytes were stained with CD132 (...
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