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PE anti-human CD304

Pricing & Availability

Analyte Specific Reagent. Analytical and performance characteristics are not established.

Clone
12C2
Other Names
BDCA-4
Isotype
Mouse IgG2a, κ
12C2_PE_CD304_ASR_032024
Typical results from human peripheral blood lymphocytes and monocytes stained either with 12C2 PE used at 5 µL/test (left) or with an isotype control (right), with anti-human CD303 APC co-staining.
  • 12C2_PE_CD304_ASR_032024
    Typical results from human peripheral blood lymphocytes and monocytes stained either with 12C2 PE used at 5 µL/test (left) or with an isotype control (right), with anti-human CD303 APC co-staining.
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988602 500 µL 322 CHF
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Description

CD304, also known as neuropilin-1, BDCA-4 and VEGF165R, is a 140 kD type I transmembrane protein. Its extracellular region contains 2 CUB, 2 FV/FVIII, and one MAM domain; a soluble isoform is produced by alternative mRNA splicing. CD304 is involved in angiogenesis, neural development, and tumor metastasis. It's expressed by plasmacytoid dendritic cells, thymocytes, neurons, endothelium, and a subset of TFH cells. CD304 is also expressed in several carcinomas, and a high expression of this molecule in prostate cancer correlates with a poor prognosis.

Product Details
Technical Data Sheet (pdf)

Product Details

Reactivity
Human
Formulation
Phosphate-buffered solution, pH 7.2, 0.09% sodium azide, 0.2% (w/v) BSA (origin USA), and a stabilizer.
Preparation
The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
Concentration
25 µg/mL
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

Suggested for Flow Cytometry
Disclaimer

WARNINGS AND PRECAUTIONS

  1. Use appropriate personal protective equipment and safety practices per universal precautions when working with this reagent. Refer to the reagent safety data sheet.
  2. This antibody contains sodium azide. Follow federal, state and local regulations to dispose of this reagent. Sodium azide build-up in metal wastepipes may lead to explosive conditions; if disposing of reagent down wastepipes, flush with water after disposal.
  3. All specimens, samples and any material coming in contact with them should be considered potentially infectious and should be disposed of with proper precautions and in accordance with federal, state and local regulations.
  4. Do not use this reagent beyond the expiration date stated on the label.
  5. Do not use this reagent if it appears cloudy or if there is any change in the appearance of the reagent as these may be an indication of possible deterioration.
  6. Avoid prolonged exposure of the reagent or stained cells to light.

Antigen Details

Antigen References
  1. Mizui M and Kikutani H. 2008. Immunity. 28:302-3.
  2. Hamerlik P, et al. 2012. J Exp Med. 209:507-20.
  3. Karjalainen K, et al. 2011. Blood. 117:920-7.
  4. Lepelletier Y, et al. 2007. P Natl Acad Sci USA. 104:5545.
Go To Top Version: 1    Revision Date: 05.01.2024

Analyte Specific Reagent. Analytical and performance characteristics are not established.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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