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PE anti-human CD368 (CLEC4D) Antibody

Pricing & Availability
Clone
9B9 (See other available formats)
Regulatory Status
RUO
Workshop
HCDM listed
Other Names
C-type lectin domain family 4 member D, CLEC6, CLECSF8, MCL, MPCL, Dectin-3, CD368
Isotype
Mouse IgG2b, κ
Ave. Rating
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Product Citations
publications
9B9_PE_CLEC4D_Antibody_FC_082013
Human peripheral blood granulocytes were stained with anti-human CD368 (CLEC4D, clone 9B9) PE (filled histogram) or mouse IgG2b, κ PE isotype control (open histogram).
  • 9B9_PE_CLEC4D_Antibody_FC_082013
    Human peripheral blood granulocytes were stained with anti-human CD368 (CLEC4D, clone 9B9) PE (filled histogram) or mouse IgG2b, κ PE isotype control (open histogram).
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360204 100 tests 293 CHF
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Description

CD368 (CLEC4D), also known as CLEC6, is a 30 kD single pass type II transmembrane protein and member of the C-type lectin-like domain (CTLD) superfamily. CLEC4D is an endocytic receptor, probably involved in antigen presentation, cell adhesion, and cell signaling. CLEC4D is expressed by macrophages, monocytes, neutrophils, and a subset of dendritic cells and is upregulated by IL-6, IL-10, TNF-α, and IFN-γ.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
CLEC4D ectodomain:IgG Fc fusion protein
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
RRID
AB_2562510 (BioLegend Cat. No. 360204)

Antigen Details

Structure
Member of the C-type lectin-like domain (CTLD) superfamily, single pass type II transmembrane protein, 30 kD
Distribution

Macrophages, monocytes, neutrophils, subset of dendritic cells; low expression in peripheral blood lymphocytes

Function
Endocytic receptor, probably involved in antigen presentation, cell adhesion, and cell signaling
Cell Type
Macrophages, Monocytes, Neutrophils, Dendritic cells
Biology Area
Immunology, Innate Immunity
Molecular Family
CD Molecules
Antigen References

1. Zhu LL, et al. 2013. Immunity 39:11.
2. Graham LM, et al. 2012. J. Biol. Chem. 287:25964.
3. Arce I, et al. 2004. Eur. J. Immunol. 34:210.

Gene ID
338339 View all products for this Gene ID
UniProt
View information about CD368 on UniProt.org

Related FAQs

What type of PE do you use in your conjugates?
We use R-PE in our conjugates.
Go To Top Version: 2    Revision Date: 01.14.2015

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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