PE anti-human MSC and NPC (W4A5) Antibody

Pricing & Availability
Clone
W4A5 (See other available formats)
Regulatory Status
RUO
Other Names
Mesenchymal Stem Cells and Neural Progenitor Cells
Isotype
Mouse IgG1, κ
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Product Citations
publications
W4A5_PE_021808
Human retinoblastoma cell line Weri-RB cells stained W4A5 PE
  • W4A5_PE_021808
    Human retinoblastoma cell line Weri-RB cells stained W4A5 PE
See PE spectral data
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330806 100 tests 317 CHF
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Description

The W4A5 antibody was generated by immunization with Weri-RB-1 cells. It reacts with a subpopulation of mesenchymal stem cells and neural progenitor cells (NPCs). Mesenchymal stem cells or MSCs are originally name as bone marrow stromal cells. They are a population of adult stem cells with a large capacity for self-renewal and multipotency for differentiation into a variety of cell types including osteoblasts, chondrocytes, myocytes, adipocytes, β-pancreatic islets cells and certain neuronal cells. MSCs reside in many tissues, such as bone marrow, placenta, adipose tissue, adult peripheral blood, fetal blood, skin, as well as liver and lung. Besides their plasticity for tissue repair, MSCs also exhibit a powerful immunosuppressive activity and play important role in supporting hematopoiesis. NPCs can give rise to astrocytes, neurons, and oligodendrocytes

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Human
Reported Reactivity
African Green, Baboon, Cynomolgus, Rhesus
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Retinoblastoma cell line (Weri-RB-1 cells)
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
RRID
AB_940642 (BioLegend Cat. No. 330806)

Antigen Details

Distribution

Subpopulation of mesenchymal stem cells and neural progenitor cells

Cell Type
Mesenchymal Stem Cells
Biology Area
Immunology, Stem Cells
Antigen References

1. Buhring HJ, et al. 2007. Ann. N. Y. Acad. Sci. 1106:262.
2. Jackson L, et al. 2007 J. Postgrad. Med. 53:121.
3. Krampera M, et al. 2003 Blood 101:3722.
4. Ball LM, et al. 2007 Blood 110:2764

Gene ID
NA
UniProt
View information about MSC on UniProt.org

Related FAQs

What type of PE do you use in your conjugates?
We use R-PE in our conjugates.
Go To Top Version: 2    Revision Date: 09.02.2022

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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