- Clone
- 76-2-11 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- CD8a, Leu2 T-lymphocyte antigen, LEU2, MAL, T8, CD8α
- Isotype
- Mouse IgG2a, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
![76-2-11_PE_CD8alpha_Antibody_072622 76-2-11_PE_CD8alpha_Antibody_072622](https://d1spbj2x7qk4bg.cloudfront.net/Admin/Public/GetImage.ashx?Image=/Files/Images/media_assets/products/product_images/76-2-11_PE_CD8alpha_Antibody_072622.png&Width=240&Height=300&altFmImage_path=&Compression=90&Crop=5)
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Porcine peripheral blood lymphocytes were stained with anti-pig CD4a FITC and anti-pig CD8 (clone 76-2-11) PE (left), or mouse IgG1, κ PE isotype control (right).
Cat # | Size | Price | Quantity Check Availability | Save | ||
---|---|---|---|---|---|---|
251203 | 25 µg | 138 CHF | ||||
251204 | 100 µg | 242 CHF |
CD8 is a 35 kD type I transmembrane glycoprotein and is expressed as either a CD8αα homodimer or a CD8αβ heterodimer. It functions as a MHC Class I co-receptor for antigen recognition. It is highly expressed in thymocytes, cytotoxic T-cells, and NK cells.
Product DetailsProduct Details
- Verified Reactivity
- Pig
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
- Preparation
- The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
- Concentration
- 0.2 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.125 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
-
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- RRID
-
AB_2924500 (BioLegend Cat. No. 251203)
AB_2924500 (BioLegend Cat. No. 251204)
Antigen Details
- Structure
- Type I transmembrane glycoprotein, expressed as CD8αα homodimer or a CD8αβ heterodimer
- Distribution
-
Thymocytes, suppressor/cytotoxic subpopulation of peripheral T cells
- Function
- Co-receptor, stabilizes MHC Class I-TCR interaction
- Ligand/Receptor
- T-cell receptors, MHC-I
- Cell Type
- NK cells, T cells, Thymocytes
- Biology Area
- Immunology
- Molecular Family
- CD Molecules
- Antigen References
-
- Wang W, et al. 2015. Mol Genet Genomics. 290:1447-56.
- Gene ID
- 396627 View all products for this Gene ID
- UniProt
- View information about CD8 on UniProt.org
Related FAQs
- What type of PE do you use in your conjugates?
- We use R-PE in our conjugates.
Other Formats
View All CD8 Reagents Request Custom ConjugationDescription | Clone | Applications |
---|---|---|
Purified anti-pig CD8 | 76-2-11 | FC |
PE anti-pig CD8 | 76-2-11 | FC |
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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Purified anti-pig CD8
Porcine peripheral blood lymphocytes were stained with anti-... -
PE anti-pig CD8
Porcine peripheral blood lymphocytes were stained with anti-...
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