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PE anti-PLCγ2 Phospho (Tyr759) Recombinant Antibody

Pricing & Availability
Clone
QA20A56 (See other available formats)
Regulatory Status
RUO
Other Names
PLCG2, APLAID, FCAS3, PLC-IV
Isotype
Mouse IgG1, κ
Ave. Rating
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Product Citations
publications
QA20A56_PE_PLCgamma2_Antibody_033122
Ramos cells (a Burkitts Lymphoma cell line) were treated with (filled histogram) or left untreated (open histogram) by anti-human IgM (H+L chain) (Cat. No. 397302) for 5 minutes. Cells were fixed with Fixation Buffer (Cat. No. 420801), permeabilized with Intracellular Staining Permeabilization Wash Buffer (Cat. No. 421002), and then intracellularly stained with PE anti-PLCγ2 Phospho (Tyr 759) recombinant (clone QA20A56).
  • QA20A56_PE_PLCgamma2_Antibody_033122
    Ramos cells (a Burkitts Lymphoma cell line) were treated with (filled histogram) or left untreated (open histogram) by anti-human IgM (H+L chain) (Cat. No. 397302) for 5 minutes. Cells were fixed with Fixation Buffer (Cat. No. 420801), permeabilized with Intracellular Staining Permeabilization Wash Buffer (Cat. No. 421002), and then intracellularly stained with PE anti-PLCγ2 Phospho (Tyr 759) recombinant (clone QA20A56).
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380903 25 tests 202 CHF
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Description

PLCγ2 is a member of the PLC family. PLCγ is the only member that contains SH2 and SH3 domains, which enable it to interact with protein tyrosine kinases and become activated by phosphorylation. PLCγ2 is expressed primarily on hematopoietic stem cells and on B cells. PLCγ2 catalyzes the hydrolysis of phospholipids to yield second messenger molecules diacylglycerol (DAG) and inositol triphosphate (IP3).

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Human, Mouse
Antibody Type
Recombinant
Host Species
Mouse
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

ICFC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by intracellular immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
RRID
AB_2922612 (BioLegend Cat. No. 380903)

Antigen Details

Distribution

B cells

Function
Cell signaling
Antigen References
  1. Kurosaki T, et al. 2000. Immunol Rev. 176:19-29.
  2. Noh DY, et al. 1995, Biochim Biophys Acta. 1242:99-113.
  3. Kang JS, et al. 1996, FEBS Lett. 399:14-20.
Gene ID
5336 View all products for this Gene ID
UniProt
View information about PLCgamma2 Phospho Tyr759 on UniProt.org

Related FAQs

What type of PE do you use in your conjugates?
We use R-PE in our conjugates.
Go To Top Version: 1    Revision Date: 03.31.2022

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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